Julia Jarrard Scialla, MD

Adjunct Associate Professor in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, Rm 7042, Durham, NC 27705
Phone (919) 668-8764
Email address julia.scialla@duke.edu

Dr. Scialla is an Associate Professor of Medicine in Nephrology at Duke University and a faculty member at the Duke Clinical Research Institute.  Dr. Scialla trained in Internal Medicine, Nephrology, and Clinical Epidemiology at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.  Her research focuses on chronic kidney disease (CKD) epidemiology and prevention, with an emphasis on the role of metabolic complications and nutrition. Current studies are focused on treatment and prevention of abnormal phosphate homeostasis, acid-base physiology, diabetic and other forms of kidney disease, and outcomes in end-stage kidney disease. 

Dr. Scialla’s work engages a number of study designs including prospective cohort studies, observational comparative effectiveness studies, and patient-oriented physiologic studies. She has worked closely with multiple chronic disease cohorts including the Chronic Renal Insufficiency Cohort (CRIC) Study, the African American Study of Kidney Disease and Hypertension (AASK), the Jackson Heart Study (JHS), and secondary analyses in clinical trials. Studies in electronic health records (EHR) and registries have engaged dialysis EHR data, the United States Renal Data System, and public registries, such as the National Health and Nutrition Examination Survey. Physiologic studies include the Acid Base Complication in CKD Study, secondary analyses in the DASH Mechanism Study, and the newly launched MURDOCK Kidney Health Study.

Education and Training

  • Nephrology, Fellowship, Johns Hopkins University School of Medicine, 2006 - 2010
  • Residency, Internal Medicine, Johns Hopkins University School of Medicine, 2003 - 2006
  • M.H.S., Johns Hopkins Unversity, Bloomberg School of Public Health, 2010
  • M.D., University of Pennsylvania, 2003

Publications

Zhang, Jing, Tobias Fuhrer, Hongping Ye, Brian Kwan, Daniel Montemayor, Jana Tumova, Manjula Darshi, et al. “High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study.” Am J Nephrol 53, no. 2–3 (2022): 215–25. https://doi.org/10.1159/000521940.

PMID
35196658
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Lunyera, Joseph, Clarissa J. Diamantidis, Hayden B. Bosworth, Uptal D. Patel, James Bain, Michael J. Muehlbauer, Olga Ilkayeva, et al. “Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease.” Metabolomics 18, no. 1 (December 20, 2021): 5. https://doi.org/10.1007/s11306-021-01858-4.

PMID
34928443
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Bhavsar, Nrupen A., Clemontina A. Davenport, Lexie Zidanyue Yang, Sarah Peskoe, Julia J. Scialla, Rasheeda K. Hall, Crystal C. Tyson, et al. “Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.” Bmc Nephrol 22, no. 1 (November 11, 2021): 375. https://doi.org/10.1186/s12882-021-02594-6.

PMID
34763649
Full Text

Hein, Aaron M., Julia J. Scialla, Jie-Lena Sun, Stephen J. Greene, Linda K. Shaw, Karen Chiswell, Patrick H. Pun, and Robert J. Mentz. “Estimated Glomerular Filtration Rate Variability in Patients With Heart Failure and Chronic Kidney Disease.” J Card Fail 27, no. 11 (November 2021): 1175–84. https://doi.org/10.1016/j.cardfail.2021.04.016.

PMID
33971291
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Grams, Morgan E., Aditya Surapaneni, Lawrence J. Appel, James P. Lash, Jesse Hsu, Clarissa J. Diamantidis, Sylvia E. Rosas, et al. “Clinical events and patient-reported outcome measures during CKD progression: findings from the Chronic Renal Insufficiency Cohort Study.” Nephrol Dial Transplant 36, no. 9 (August 27, 2021): 1685–93. https://doi.org/10.1093/ndt/gfaa364.

PMID
33326030
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Tyson, Crystal C., Alison Luciano, Jennifer L. Modliszewski, David L. Corcoran, James R. Bain, Michael Muehlbauer, Olga Ilkayeva, et al. “Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.” Am J Kidney Dis 78, no. 1 (July 2021): 38–47. https://doi.org/10.1053/j.ajkd.2020.10.015.

PMID
33810868
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Hall, Rasheeda K., Sarah Morton, Jonathan Wilson, Patti L. Ephraim, L Ebony Boulware, Wendy L. St Peter, Cathleen Colón-Emeric, Jane Pendergast, and Julia J. Scialla. “Risks associated with continuation of potentially inappropriate antihypertensive medications in older adults receiving hemodialysis.” Bmc Nephrol 22, no. 1 (June 19, 2021): 232. https://doi.org/10.1186/s12882-021-02438-3.

PMID
34147085
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Pourafshar, Shirin, Mira Nicchitta, Crystal C. Tyson, Laura P. Svetkey, David L. Corcoran, James R. Bain, Michael J. Muehlbauer, et al. “Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study.” Nutrients 13, no. 6 (May 22, 2021). https://doi.org/10.3390/nu13061768.

PMID
34067295
Full Text

Oluwo, Oluwaseun, and Julia J. Scialla. “Uric Acid and CKD Progression Matures with Lessons for CKD Risk Factor Discovery.” Clin J Am Soc Nephrol 16, no. 3 (March 8, 2021): 476–78. https://doi.org/10.2215/CJN.10650620.

PMID
33055190
Full Text

Pages