Julia Jarrard Scialla, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, Rm 7042, Durham, NC 27705
Phone (919) 668-8764
Email address julia.scialla@duke.edu

Dr. Scialla is an Associate Professor of Medicine in Nephrology at Duke University and a faculty member at the Duke Clinical Research Institute.  Dr. Scialla trained in Internal Medicine, Nephrology, and Clinical Epidemiology at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.  Her research focuses on chronic kidney disease (CKD) epidemiology and prevention, with an emphasis on the role of metabolic complications and nutrition. Current studies are focused on treatment and prevention of abnormal phosphate homeostasis, acid-base physiology, diabetic and other forms of kidney disease, and outcomes in end-stage kidney disease. 

Dr. Scialla’s work engages a number of study designs including prospective cohort studies, observational comparative effectiveness studies, and patient-oriented physiologic studies. She has worked closely with multiple chronic disease cohorts including the Chronic Renal Insufficiency Cohort (CRIC) Study, the African American Study of Kidney Disease and Hypertension (AASK), the Jackson Heart Study (JHS), and secondary analyses in clinical trials. Studies in electronic health records (EHR) and registries have engaged dialysis EHR data, the United States Renal Data System, and public registries, such as the National Health and Nutrition Examination Survey. Physiologic studies include the Acid Base Complication in CKD Study, secondary analyses in the DASH Mechanism Study, and the newly launched MURDOCK Kidney Health Study.

Education and Training

  • Nephrology, Fellowship, Johns Hopkins University School of Medicine, 2006 - 2010
  • Residency, Internal Medicine, Johns Hopkins University School of Medicine, 2003 - 2006
  • M.H.S., Johns Hopkins Bloomberg School of Public Health, 2010
  • M.D., University of Pennsylvania, 2003

Publications

Isakova, T, Xie, H, Messinger, S, Cortazar, F, Scialla, JJ, Guerra, G, Contreras, G, Roth, D, Burke, GW, Molnar, MZ, Mucsi, I, and Wolf, M. "Inhibitors of mTOR and risks of allograft failure and mortality in kidney transplantation." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 13, no. 1 (January 2013): 100-110.

PMID
23025566
Full Text

Boulware, LE, Tangri, N, Ephraim, PL, Scialla, JJ, Sozio, SM, Crews, DC, Shafi, T, Miskulin, DC, Liu, J, St Peter, W, Jaar, BG, Wu, AW, Powe, NR, Navaneethan, SD, Bandeen-Roche, K, and DEcIDE ESRD Patient Outcomes in Renal Disease Study Investigators, . "Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study." Bmc Nephrology 13 (December 6, 2012): 167-null.

PMID
23217181
Full Text

Scialla, JJ, Appel, LJ, Wolf, M, Yang, W, Zhang, X, Sozio, SM, Miller, ER, Bazzano, LA, Cuevas, M, Glenn, MJ, Lustigova, E, Kallem, RR, Porter, AC, Townsend, RR, Weir, MR, Anderson, CAM, and Chronic Renal Insufficiency Cohort-CRIC Study Group, . "Plant protein intake is associated with fibroblast growth factor 23 and serum bicarbonate levels in patients with chronic kidney disease: the Chronic Renal Insufficiency Cohort study." Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation 22, no. 4 (July 2012): 379-388.e1.

PMID
22480598
Full Text

Scialla, JJ, Appel, LJ, Astor, BC, Miller, ER, Beddhu, S, Woodward, M, Parekh, RS, Anderson, CAM, and African American Study of Kidney Disease and Hypertension Study Group, . "Net endogenous acid production is associated with a faster decline in GFR in African Americans." Kidney International 82, no. 1 (July 2012): 106-112.

PMID
22475819
Full Text

Wahl, P, Xie, H, Scialla, J, Anderson, CAM, Bellovich, K, Brecklin, C, Chen, J, Feldman, H, Gutierrez, OM, Lash, J, Leonard, MB, Negrea, L, Rosas, SE, Anderson, AH, Townsend, RR, Wolf, M, Isakova, T, and Chronic Renal Insufficiency Cohort Study Group, . "Earlier onset and greater severity of disordered mineral metabolism in diabetic patients with chronic kidney disease." Diabetes Care 35, no. 5 (May 2012): 994-1001.

PMID
22446176
Full Text

Scialla, JJ, Leonard, MB, Townsend, RR, Appel, L, Wolf, M, Budoff, MJ, Chen, J, Lustigova, E, Gadegbeku, CA, Glenn, M, Hanish, A, Raj, D, Rosas, SE, Seliger, SL, Weir, MR, Parekh, RS, and CRIC Study Group, . "Correlates of osteoprotegerin and association with aortic pulse wave velocity in patients with chronic kidney disease." Clinical Journal of the American Society of Nephrology : Cjasn 6, no. 11 (November 2011): 2612-2619.

PMID
21940840
Full Text

Faul, C, Amaral, AP, Oskouei, B, Hu, M-C, Sloan, A, Isakova, T, Gutiérrez, OM, Aguillon-Prada, R, Lincoln, J, Hare, JM, Mundel, P, Morales, A, Scialla, J, Fischer, M, Soliman, EZ, Chen, J, Go, AS, Rosas, SE, Nessel, L, Townsend, RR, Feldman, HI, St John Sutton, M, Ojo, A, Gadegbeku, C, Di Marco, GS, Reuter, S, Kentrup, D, Tiemann, K, Brand, M, Hill, JA, Moe, OW, Kuro-O, M, Kusek, JW, Keane, MG, and Wolf, M. "FGF23 induces left ventricular hypertrophy." The Journal of Clinical Investigation 121, no. 11 (November 2011): 4393-4408.

PMID
21985788
Full Text

Scialla, JJ, Appel, LJ, Astor, BC, Miller, ER, Beddhu, S, Woodward, M, Parekh, RS, and Anderson, CAM. "Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease." Clinical Journal of the American Society of Nephrology : Cjasn 6, no. 7 (July 2011): 1526-1532.

PMID
21700817
Full Text

Isakova, T, Xie, H, Yang, W, Xie, D, Anderson, AH, Scialla, J, Wahl, P, Gutiérrez, OM, Steigerwalt, S, He, J, Schwartz, S, Lo, J, Ojo, A, Sondheimer, J, Hsu, C-Y, Lash, J, Leonard, M, Kusek, JW, Feldman, HI, Wolf, M, and Chronic Renal Insufficiency Cohort (CRIC) Study Group, . "Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease." Jama 305, no. 23 (June 2011): 2432-2439.

PMID
21673295
Full Text

Isakova, T, Wahl, P, Vargas, GS, Gutiérrez, OM, Scialla, J, Xie, H, Appleby, D, Nessel, L, Bellovich, K, Chen, J, Hamm, L, Gadegbeku, C, Horwitz, E, Townsend, RR, Anderson, CAM, Lash, JP, Hsu, C-Y, Leonard, MB, and Wolf, M. "Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease." Kidney International 79, no. 12 (June 2011): 1370-1378.

PMID
21389978
Full Text

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