Jun Chen, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail Box 103866 Med Ctr, Durham, NC 27710
Phone (919) 681-3021
Email address chen0032@mc.duke.edu

Education and Training

  • Postdoctoral Fellow, Stanford University School of Medicine, 1994 - 1996
  • M.D., Sun Yat Sen University (China), 1991

Publications

Tang, Yuning J., Jianguo Huang, Hidetoshi Tsushima, Ga I. Ban, Hongyuan Zhang, Kristianne M. Oristian, Vijitha Puviindran, et al. “Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Advanced Metastasis.” Cell Rep 28, no. 11 (September 10, 2019): 2837-2850.e5. https://doi.org/10.1016/j.celrep.2019.08.029.

PMID
31509746
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Piryani, Sadhna O., Yiqun Jiao, Angel Y. F. Kam, Yang Liu, Tuan Vo-Dinh, Benny J. Chen, Nelson J. Chao, and Phuong L. Doan. “Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.” Int J Radiat Oncol Biol Phys 104, no. 2 (June 1, 2019): 291–301. https://doi.org/10.1016/j.ijrobp.2019.02.008.

PMID
30763662
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Huang, Wei, Wenjian Mo, Jieling Jiang, Nelson J. Chao, and Benny J. Chen. “Donor Allospecific CD44high Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease.” Front Immunol 10 (2019): 624. https://doi.org/10.3389/fimmu.2019.00624.

PMID
31001254
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Liu, Yang, Wei Huang, Chuanfeng Xiong, Yuxian Huang, Benny J. Chen, Luigi Racioppi, Nelson Chao, and Tuan Vo-Dinh. “Biodistribution and sensitive tracking of immune cells with plasmonic gold nanostars.” Int J Nanomedicine 14 (2019): 3403–11. https://doi.org/10.2147/IJN.S192189.

PMID
31190799
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Poe, Jonathan C., Wei Jia, Julie A. Di Paolo, Nancy J. Reyes, Ji Yun Kim, Hsuan Su, John S. Sundy, et al. “SYK inhibitor entospletinib prevents ocular and skin GVHD in mice.” Jci Insight 3, no. 19 (October 4, 2018). https://doi.org/10.1172/jci.insight.122430.

PMID
30282825
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Piryani, Sadhna O., Angel Y. F. Kam, Evelyna G. Kliassov, Benny J. Chen, Neil L. Spector, John P. Chute, David S. Hsu, Nelson J. Chao, and Phuong L. Doan. “Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.” Stem Cells (Dayton, Ohio) 36, no. 2 (February 2018): 252–64. https://doi.org/10.1002/stem.2731.

PMID
29086459
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Sundaramoorthy, Pasupathi, Qinhong Wang, Zhihong Zheng, Yiqun Jiao, Benny J. Chen, Phuong L. Doan, Nelson J. Chao, and Yubin Kang. “Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.” Stem Cell Res Ther 8, no. 1 (November 15, 2017): 263. https://doi.org/10.1186/s13287-017-0711-2.

PMID
29141658
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Agboola, Olabunmi, Jun Chen, and M Louise Markert. “Thymus Transplantation for Chronic Graft Versus Host Disease.” In Journal of Allergy and Clinical Immunology, 139:AB185–AB185. Elsevier BV, 2017. https://doi.org/10.1016/j.jaci.2016.12.605.

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Foster, Mary H., Elizabeth S. Buckley, Benny J. Chen, Kwan-Ki Hwang, and Amy G. Clark. “Uncommon structural motifs dominate the antigen binding site in human autoantibodies reactive with basement membrane collagen.” Mol Immunol 76 (August 2016): 123–33. https://doi.org/10.1016/j.molimm.2016.07.004.

PMID
27450516
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Zhang, Baojun, Jianxuan Wu, Yiqun Jiao, Cheryl Bock, Meifang Dai, Benny Chen, Nelson Chao, Weiguo Zhang, and Yuan Zhuang. “Differential Requirements of TCR Signaling in Homeostatic Maintenance and Function of Dendritic Epidermal T Cells.” J Immunol 195, no. 9 (November 1, 2015): 4282–91. https://doi.org/10.4049/jimmunol.1501220.

PMID
26408667
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Pages