Kimberly Lynn Blackwell, MD

Adjunct Professor in the Department of Medicine
Campus mail Duke Box 3893, Durham, NC 27710
Phone (919) 668-1748
Email address black034@mc.duke.edu

Breast cancer angiogenesis
Breast cancer in younger women
Hormonal therapy
Neoadjurant therapy for breast cancer

Current Clinical Investigations

Principal Investigator, A Phase I-II Study of Neoadjuvant Evacet/Paclitaxel/Hyperthermia in Locally Advanced Breast Cancer Patients.

Investigator, Development of Screening Markers for Breast Cancer using Circulating Immune Complexes: Collaborative Study with Diagen Medical Technologies.

Principal Investigator, Use of Plasma D-Dimer as a Predictive Marker in Colorectal Carcinoma: Correlative Science Study with Genentech, Inc.

Principal Investigator, A randomized, Phase II study of gabapentin or glutamine to prevent the peripheral neuropathy/myalgia associated with weekly taxol administration in metastatic breast and lung cancer.

Investigator, A Phase 2, Randomized, Double-Masked, Multicenter Study of Two Dose Levels of ERA-923 for the treatment of Metastatic Breast Cancer in Postmenopausal Women who have failed Tamoxifen therapy. Genetics Institute.

Investigator, A Phase I Study of Combined Doxil/Hyperthermia in Stage IV Breast Cancer.

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 1997 - 2000
  • Medical Resident, Medicine, Duke University, 1994 - 1997
  • M.D., Mayo School of Health Sciences, 1994

Publications

Blackwell, Kimberly, Herbert Hurwitz, Grazyna Liebérman, William Novotny, Stacey Snyder, Mark Dewhirst, and Charles Greenberg. “Circulating D-dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma.” Cancer 101, no. 1 (July 1, 2004): 77–82. https://doi.org/10.1002/cncr.20336.

PMID
15221991
Full Text

Alvarez Secord, Angeles, Robyn Sayer, Stacey A. Snyder, Gloria Broadwater, Gustavo C. Rodriguez, Andrew Berchuck, and Kimberly Blackwell. “The relationship between serum vascular endothelial growth factor, persistent disease, and survival at second-look laparotomy in ovarian cancer.” Gynecol Oncol 94, no. 1 (July 2004): 74–79. https://doi.org/10.1016/j.ygyno.2004.03.043.

PMID
15262122
Full Text

Blackwell, Kimberly L., Mark W. Dewhirst, Vlayka Liotcheva, Stacey Snyder, Gloria Broadwater, Rex Bentley, Anita Lal, et al. “HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors.” Clin Cancer Res 10, no. 12 Pt 1 (June 15, 2004): 4083–88. https://doi.org/10.1158/1078-0432.CCR-03-0695.

PMID
15217943
Full Text

Rosen, Eric L., Kimberly L. Blackwell, Jay A. Baker, Mary Scott Soo, Rex C. Bentley, Daohai Yu, Thaddeus V. Samulski, and Mark W. Dewhirst. “Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy.” Ajr Am J Roentgenol 181, no. 5 (November 2003): 1275–82. https://doi.org/10.2214/ajr.181.5.1811275.

PMID
14573420
Full Text

Blackwell, Kimberly L., John P. Kirkpatrick, Stacey A. Snyder, Gloria Broadwater, Francis Farrell, Linda Jolliffe, David M. Brizel, and Mark W. Dewhirst. “Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin.” Cancer Res 63, no. 19 (October 1, 2003): 6162–65.

PMID
14559797
Scholars@Duke

Vujaskovic, Z., E. L. Rosen, K. L. Blackwell, E. L. Jones, D. M. Brizel, L. R. Prosnitz, T. V. Samulski, and M. W. Dewhirst. “Ultrasound guided pO2 measurement of breast cancer reoxygenation after neoadjuvant chemotherapy and hyperthermia treatment.” Int J Hyperthermia 19, no. 5 (September 2003): 498–506. https://doi.org/10.1080/0265673031000121517.

PMID
12944165
Full Text

Weber, R. S., E. Abemayor, G. L. Adams, D. J. Adelstein, A. Alavi, E. Alford, M. Al-Sarraf, et al. “Head and neck: Editorial.” Head and Neck 23, no. 12 (December 13, 2001): 1021–23. https://doi.org/10.1002/hed.1148.

Full Text

Demark-Wahnefried, W., B. L. Peterson, E. P. Winer, L. Marks, N. Aziz, P. K. Marcom, K. Blackwell, and B. K. Rimer. “Changes in weight, body composition, and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy.” J Clin Oncol 19, no. 9 (May 1, 2001): 2381–89. https://doi.org/10.1200/JCO.2001.19.9.2381.

PMID
11331316
Full Text

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