Kimberly Lynn Blackwell, MD

Adjunct Professor in the Department of Medicine
Member of the Duke Cancer Institute
Campus mail Duke Box 3893, Durham, NC 27710
Phone (919) 668-1748
Email address black034@mc.duke.edu

Breast cancer angiogenesis
Breast cancer in younger women
Hormonal therapy
Neoadjurant therapy for breast cancer

Current Clinical Investigations

Principal Investigator, A Phase I-II Study of Neoadjuvant Evacet/Paclitaxel/Hyperthermia in Locally Advanced Breast Cancer Patients.

Investigator, Development of Screening Markers for Breast Cancer using Circulating Immune Complexes: Collaborative Study with Diagen Medical Technologies.

Principal Investigator, Use of Plasma D-Dimer as a Predictive Marker in Colorectal Carcinoma: Correlative Science Study with Genentech, Inc.

Principal Investigator, A randomized, Phase II study of gabapentin or glutamine to prevent the peripheral neuropathy/myalgia associated with weekly taxol administration in metastatic breast and lung cancer.

Investigator, A Phase 2, Randomized, Double-Masked, Multicenter Study of Two Dose Levels of ERA-923 for the treatment of Metastatic Breast Cancer in Postmenopausal Women who have failed Tamoxifen therapy. Genetics Institute.

Investigator, A Phase I Study of Combined Doxil/Hyperthermia in Stage IV Breast Cancer.

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 1997 - 2000
  • Medical Resident, Medicine, Duke University, 1994 - 1997
  • M.D., Mayo School of Health Sciences, 1994

Publications

Blackwell, Kimberly L., Mark W. Dewhirst, Vlayka Liotcheva, Stacey Snyder, Gloria Broadwater, Rex Bentley, Anita Lal, et al. “HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors..” Clin Cancer Res 10, no. 12 Pt 1 (June 15, 2004): 4083–88. https://doi.org/10.1158/1078-0432.CCR-03-0695.

PMID
15217943
Full Text

Rosen, Eric L., Kimberly L. Blackwell, Jay A. Baker, Mary Scott Soo, Rex C. Bentley, Daohai Yu, Thaddeus V. Samulski, and Mark W. Dewhirst. “Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy..” Ajr Am J Roentgenol 181, no. 5 (November 2003): 1275–82. https://doi.org/10.2214/ajr.181.5.1811275.

PMID
14573420
Full Text

Blackwell, Kimberly L., John P. Kirkpatrick, Stacey A. Snyder, Gloria Broadwater, Francis Farrell, Linda Jolliffe, David M. Brizel, and Mark W. Dewhirst. “Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin..” Cancer Res 63, no. 19 (October 1, 2003): 6162–65.

PMID
14559797
Scholars@Duke

Vujaskovic, Z., E. L. Rosen, K. L. Blackwell, E. L. Jones, D. M. Brizel, L. R. Prosnitz, T. V. Samulski, and M. W. Dewhirst. “Ultrasound guided pO2 measurement of breast cancer reoxygenation after neoadjuvant chemotherapy and hyperthermia treatment..” Int J Hyperthermia 19, no. 5 (September 2003): 498–506. https://doi.org/10.1080/0265673031000121517.

PMID
12944165
Full Text

Weber, R. S., E. Abemayor, G. L. Adams, D. J. Adelstein, A. Alavi, E. Alford, M. Al-Sarraf, et al. “Head and neck: Editorial.” Head and Neck 23, no. 12 (December 13, 2001): 1021–23. https://doi.org/10.1002/hed.1148.

Full Text

Demark-Wahnefried, W., B. L. Peterson, E. P. Winer, L. Marks, N. Aziz, P. K. Marcom, K. Blackwell, and B. K. Rimer. “Changes in weight, body composition, and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 19, no. 9 (May 2001): 2381–89. https://doi.org/10.1200/jco.2001.19.9.2381.

PMID
11331316
Full Text

Blackwell, K. L., Z. A. Haroon, S. Shan, W. Saito, G. Broadwater, C. S. Greenberg, and M. W. Dewhirst. “Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models..” Clin Cancer Res 6, no. 11 (November 2000): 4359–64.

PMID
11106254
Scholars@Duke

Blackwell, K., Z. Haroon, G. Broadwater, D. Berry, L. Harris, J. D. Iglehart, M. Dewhirst, and C. Greenberg. “Plasma D-dimer levels in operable breast cancer patients correlate with clinical stage and axillary lymph node status..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 18, no. 3 (February 2000): 600–608. https://doi.org/10.1200/jco.2000.18.3.600.

PMID
10653875
Full Text

Pages