Kuo Du, PhD

Publications

Du, Kuo, Seh Hoon Oh, Rajesh K. Dutta, Tianai Sun, Wen-Hsuan Yang, Jen-Tsan Chi, and Anna Mae Diehl. “Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury.” Liver Int 41, no. 9 (September 2021): 2214–27. https://doi.org/10.1111/liv.14945.

PMID
33991158
Full Text

Nguyen, Nga T., Kuo Du, Jephte Y. Akakpo, David S. Umbaugh, Hartmut Jaeschke, and Anup Ramachandran. “Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice.” Toxicol Lett 338 (March 1, 2021): 21–31. https://doi.org/10.1016/j.toxlet.2020.12.005.

PMID
33290831
Full Text

Hyun, Jeongeun, Zhaoli Sun, Ali Reza Ahmadi, Sushant Bangru, Ullas V. Chembazhi, Kuo Du, Tianyi Chen, et al. “Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.” J Clin Invest 130, no. 4 (April 1, 2020): 2129–45. https://doi.org/10.1172/JCI132691.

PMID
31945016
Full Text

Liu, Xue-Jing, Li Xie, Kuo Du, Chang Liu, Ning-Ping Zhang, Chen-Jian Gu, Ying Wang, et al. “Succinate-GPR-91 receptor signalling is responsible for nonalcoholic steatohepatitis-associated fibrosis: Effects of DHA supplementation.” Liver Int 40, no. 4 (April 2020): 830–43. https://doi.org/10.1111/liv.14370.

PMID
31903720
Full Text

Jewell, Mark L., Jason R. Gibson, Cynthia D. Guy, Jeongeun Hyun, Kuo Du, Seh-Hoon Oh, Richard T. Premont, et al. “Single-Cell RNA Sequencing Identifies Yes-Associated Protein 1-Dependent Hepatic Mesothelial Progenitors in Fibrolamellar Carcinoma.” Am J Pathol 190, no. 1 (January 2020): 93–107. https://doi.org/10.1016/j.ajpath.2019.09.018.

PMID
31669305
Full Text

Du, Kuo, Satish K. Chitneni, Ayako Suzuki, Ying Wang, Ricardo Henao, Jeongeun Hyun, Richard T. Premont, et al. “Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.” Cell Mol Gastroenterol Hepatol 10, no. 1 (2020): 1–21. https://doi.org/10.1016/j.jcmgh.2019.12.006.

PMID
31881361
Full Text

Du, Kuo, Anup Ramachandran, James L. Weemhoff, Benjamin L. Woolbright, Andrew H. Jaeschke, Xiaojuan Chao, Wen-Xing Ding, and Hartmut Jaeschke. “Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity.” Arch Toxicol 93, no. 1 (January 2019): 163–78. https://doi.org/10.1007/s00204-018-2331-8.

PMID
30324313
Full Text

Du, Kuo, Jeongeun Hyun, Richard T. Premont, Steve S. Choi, Gregory A. Michelotti, Marzena Swiderska-Syn, George D. Dalton, et al. “Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.” In Gastroenterology, 154:1465-1479.e13, 2018. https://doi.org/10.1053/j.gastro.2017.12.022.

PMID
29305935
Full Text

Du, Kuo, Anup Ramachandran, Mitchell R. McGill, Abdellah Mansouri, Tarik Asselah, Anwar Farhood, Benjamin L. Woolbright, Wen-Xing Ding, and Hartmut Jaeschke. “Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.” Food Chem Toxicol 108, no. Pt A (October 2017): 339–50. https://doi.org/10.1016/j.fct.2017.08.020.

PMID
28827156
Full Text

Duan, Luqi, John S. Davis, Benjamin L. Woolbright, Kuo Du, Mala Cahkraborty, James Weemhoff, Hartmut Jaeschke, and Mohammed Bourdi. “Corrigendum to "Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J" [Food and Chem. Toxicol. 98 (Part B) (2016) 107-118].” Food Chem Toxicol 103 (May 2017): 289. https://doi.org/10.1016/j.fct.2017.03.032.

PMID
28359650
Full Text

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