Laura Kristin Newby, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Duke Box 3213, Durham, NC 27710
Phone (919) 668-8805
Email address newby001@mc.duke.edu

Research Description

General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.

Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1990 - 1993
  • Medical Resident, Medicine, Duke University, 1987 - 1990
  • M.D., Indiana University at Indianapolis, 1987

Publications

Samman, Karla N., Pamela Mehanna, Emad Takla, Jean-Christophe Grenier, Mark Y. Chan, Renato D. Lopes, Megan Lee Neely, et al. “Differential modulation of polyunsaturated fatty acids in patients with myocardial infarction treated with ticagrelor or clopidogrel.” Cell Rep Med 2, no. 6 (June 15, 2021): 100299. https://doi.org/10.1016/j.xcrm.2021.100299.

PMID
34195679
Full Text

Giarraputo, James, Stephanie Giamberardino, Stephanie Arvai, Sarah Maichle, Christopher Eckstein, L Kristin Newby, and Simon Gregory. “Profiling serum neurofilament light chain and glial fibrillary acidic protein in primary progressive multiple sclerosis.” J Neuroimmunol 354 (May 15, 2021): 577541. https://doi.org/10.1016/j.jneuroim.2021.577541.

PMID
33725477
Full Text

Sliwa, Karen, Kavita Singh, Lana Raspail, Dike Ojji, Carolyn S. P. Lam, Friedrich Thienemann, Junbo Ge, et al. “The World Heart Federation Global Study on COVID-19 and Cardiovascular Disease.” Glob Heart 16, no. 1 (April 19, 2021): 22. https://doi.org/10.5334/gh.950.

PMID
34040935
Full Text

Kansal, Aman, Cynthia L. Green, Eric D. Peterson, L Kristin Newby, Tracy Y. Wang, Mark Sendak, Suresh Balu, Manesh R. Patel, and Alexander C. Fanaroff. “Electronic Health Record Integration of Predictive Analytics to Select High-Risk Stable Patients With Non-ST-Segment-Elevation Myocardial Infarction for Intensive Care Unit Admission.” Circ Cardiovasc Qual Outcomes 14, no. 4 (April 2021): e007602. https://doi.org/10.1161/CIRCOUTCOMES.120.007602.

PMID
33757310
Full Text

Nanna, Michael G., and L Kristin Newby. “In coronary artery disease, PCI increases all-cause and cause-specific mortality compared with CABG.” Ann Intern Med 174, no. 3 (March 2021): JC27. https://doi.org/10.7326/ACPJ202103160-027.

PMID
33646845
Full Text

Cushman, Mary, Christina M. Shay, Virginia J. Howard, Monik C. Jiménez, Jennifer Lewey, Jean C. McSweeney, L Kristin Newby, et al. “Ten-Year Differences in Women's Awareness Related to Coronary Heart Disease: Results of the 2019 American Heart Association National Survey: A Special Report From the American Heart Association.” Circulation 143, no. 7 (February 16, 2021): e239–48. https://doi.org/10.1161/CIR.0000000000000907.

PMID
32954796
Full Text

Koshizaka, Masaya, Ko Ishikawa, Ryoichi Ishibashi, Yoshiro Maezawa, Kenichi Sakamoto, Daigaku Uchida, Susumu Nakamura, et al. “Effects of ipragliflozin versus metformin in combination with sitagliptin on bone and muscle in Japanese patients with type 2 diabetes mellitus: Subanalysis of a prospective, randomized, controlled study (PRIME-V study).” J Diabetes Investig 12, no. 2 (February 2021): 200–206. https://doi.org/10.1111/jdi.13340.

PMID
32623839
Full Text

Kelsey, Michelle D., and L Kristin Newby. “In patients at high CV risk receiving simvastatin, the Myopathy Risk Score predicted statin-related myopathy.” Ann Intern Med 173, no. 12 (December 15, 2020): JC71. https://doi.org/10.7326/ACPJ202012150-071.

PMID
33316194
Full Text

Douglas, Teresa D., L Kristin Newby, Julie Eckstrand, Douglas Wixted, and Rani H. Singh. “Lipid changes in the metabolome of a single case study with maple syrup urine disease (MSUD) after five days of improved diet adherence of controlled branched-chain amino acids (BCAA).” Mol Genet Metab Rep 25 (December 2020): 100651. https://doi.org/10.1016/j.ymgmr.2020.100651.

PMID
33088714
Full Text

Kelsey, Michelle D., and L Kristin Newby. “In older patients with NSTE-ACS, clopidogrel safely reduced bleeding compared with ticagrelor at 1 year.” Ann Intern Med 173, no. 6 (September 15, 2020): JC28. https://doi.org/10.7326/ACPJ202009150-028.

PMID
32926825
Full Text

Pages