Laura Kristin Newby, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Duke Box 3213, Durham, NC 27710
Phone (919) 668-8805
Email address newby001@mc.duke.edu

Research Description

General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.

Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics

In Their Words

Education and Training

  • Fellow In Cardiology, Medicine, Duke University, 1990 - 1993
  • Medical Resident, Medicine, Duke University, 1987 - 1990
  • M.D., Indiana University at Indianapolis, 1987

Publications

Koshizaka, M, Lopes, RD, Newby, LK, Clare, RM, Schulte, PJ, Tricoci, P, Mahaffey, KW, Ogawa, H, Moliterno, DJ, Giugliano, RP, Huber, K, James, S, Harrington, RA, and Alexander, JH. "Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites." The American journal of medicine 130, no. 10 (October 2017): 1170-1176.

PMID
28396226
Full Text

Lowenstern, A, and Newby, LK. "To Pretreat or Not to Pretreat (With Oral P2Y12 Antagonists)? That is the Question." Journal of the American Heart Association 6, no. 9 (September 22, 2017).

PMID
28939720
Full Text

Hachey, BJ, Kontos, MC, Newby, LK, Christenson, RH, Peacock, WF, Brewer, KC, and McCord, J. "Trends in Use of Biomarker Protocols for the Evaluation of Possible Myocardial Infarction." Journal of the American Heart Association 6, no. 9 (September 22, 2017).

PMID
28939707
Full Text

Lowenstern, A, and Newby, LK. "In PCI-treated ACS, switching from aspirin + a newer P2Y12 blocker to aspirin + clopidogrel reduced adverse events." Annals of Internal Medicine 167, no. 6 (September 19, 2017): JC28-.

Full Text

Rymer, JA, and Newby, LK. "Failure to Launch: Targeting Inflammation in Acute Coronary Syndromes." JACC: Basic to Translational Science 2, no. 4 (August 1, 2017): 484-497. (Review)

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Bagai, A, Alexander, KP, Berger, JS, Senior, R, Sajeev, C, Pracon, R, Mavromatis, K, Lopez-Sendón, JL, Gosselin, G, Diaz, A, Perna, G, Drozdz, J, Humen, D, Petrauskiene, B, Cheema, AN, Phaneuf, D, Banerjee, S, Miller, TD, Kedev, S, Schuchlenz, H, Stone, GW, Goodman, SG, Mahaffey, KW, Jaffe, AS, Rosenberg, YD, Bangalore, S, Newby, LK, Maron, DJ, Hochman, JS, and Chaitman, BR. "Use of troponin assay 99th percentile as the decision level for myocardial infarction diagnosis." American heart journal 190 (August 2017): 135-139.

PMID
28760208
Full Text

van Diepen, S, Fordyce, CB, Wegermann, ZK, Granger, CB, Stebbins, A, Morrow, DA, Solomon, MA, Soble, J, Henry, TD, Gilchrist, IC, Katz, JN, Cohen, MG, and Newby, LK. "Organizational Structure, Staffing, Resources, and Educational Initiatives in Cardiac Intensive Care Units in the United States: An American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical Care Cardiology Working Group Cross-Sectional Survey." Circulation. Cardiovascular quality and outcomes 10, no. 8 (August 2017): e003864-.

PMID
28794122
Full Text

Musunuru, K, Ingelsson, E, Fornage, M, Liu, P, Murphy, AM, Newby, LK, Newton-Cheh, C, Perez, MV, Voora, D, Woo, D, American Heart Association Committee on Molecular Determinants of Cardiovascular Health of the Council on Functional Genomics and Translational Biology and Council on Epidemiology and Prevention, Council on Cardiovascular Disease in the Young, Council on Cardiovascular and Stroke Nursing, and Council on Cardiovascular Surgery and Anesthesia, Council on Clinical Cardiology et al. "The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association." Circulation. Cardiovascular genetics 10, no. 4 (August 2017). (Review)

PMID
28760750
Full Text

Lowenstern, A, Mandawat, A, and Newby, LK. "In-Hospital Cardiac Arrest: Complex Clinical Challenges in Need of Unique Solutions." American Heart Journal (August 2017).

Full Text

Guimarães, PO, Sun, J-L, Kragholm, K, Shah, SH, Pieper, KS, Kraus, WE, Hauser, ER, Granger, CB, Kristin Newby, L, MURDOCK Horizon 1 Cardiovascular Study Investigators Durham, and NC, . "Corrigendum to 'Association of Standard Clinical and Laboratory Variables with Red Blood Cell Distribution Width (RDW)'[Am. Heart J. (2016) 22-28]." American heart journal 188 (June 2017): 196-.

PMID
28577677
Full Text

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