Cardiology

Laura Kristin Newby, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Duke Box 3213, Durham, NC 27710
Phone (919) 668-8805
Email address newby001@mc.duke.edu

Research Description

General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.

Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1990 - 1993
  • Medical Resident, Medicine, Duke University, 1987 - 1990
  • M.D., Indiana University at Indianapolis, 1987

Grants

Publications

Koshizaka, Masaya, Ko Ishikawa, Ryoichi Ishibashi, Yoshiro Maezawa, Kenichi Sakamoto, Daigaku Uchida, Susumu Nakamura, et al. “Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open-label, blinded-endpoint, randomized controlled study (PRIME-V study)..” Diabetes Obes Metab 21, no. 8 (August 2019): 1990–95. https://doi.org/10.1111/dom.13750.

PMID
30993861
Full Text

Andersen, S. L., F. B. S. Briggs, J. H. Winnike, Y. Natanzon, S. Maichle, K. J. Knagge, L. K. Newby, and S. G. Gregory. “Metabolome-based signature of disease pathology in MS..” Mult Scler Relat Disord 31 (June 2019): 12–21. https://doi.org/10.1016/j.msard.2019.03.006.

PMID
30877925
Full Text

Harskamp, Ralf E., Thomas M. Granger, Robert M. Clare, Kyle R. White, Renato D. Lopes, Karen S. Pieper, Christopher B. Granger, Christopher B. Newgard, Svati H. Shah, and L Kristin Newby. “Peripheral blood metabolite profiles associated with new onset atrial fibrillation..” Am Heart J 211 (May 2019): 54–59. https://doi.org/10.1016/j.ahj.2019.01.010.

PMID
30889527
Full Text

Januzzi, James L., Simon A. Mahler, Robert H. Christenson, Jennifer Rymer, L Kristin Newby, Richard Body, David A. Morrow, and Allan S. Jaffe. “Recommendations for Institutions Transitioning to High-Sensitivity Troponin Testing: JACC Scientific Expert Panel..” J Am Coll Cardiol 73, no. 9 (March 12, 2019): 1059–77. https://doi.org/10.1016/j.jacc.2018.12.046.

PMID
30798981
Full Text

Harrison, Robert W., and L Kristin Newby. “Rivaroxaban in Acute Coronary Syndromes: We Have a Compass and an Atlas, But Where Are We Headed?.” J Am Heart Assoc 8, no. 5 (March 5, 2019). https://doi.org/10.1161/JAHA.119.012014.

PMID
30813822
Full Text

Parker, Daniel, Richard Sloane, Carl F. Pieper, Katherine S. Hall, Virginia B. Kraus, William E. Kraus, Janet L. Huebner, et al. “Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood..” In J Gerontol a Biol Sci Med Sci, 74:283–89, 2019. https://doi.org/10.1093/gerona/gly121.

PMID
29985987
Full Text

McCord, James, L Kristin Newby, and Christopher R. deFilippi. “Response by McCord et al to Letter Regarding Article, "Designing a Better Mousetrap: Reflections on the November 28, 2017, US Food and Drug Administration Meeting on Next-Generation "High-Sensitivity" Cardiac Troponin Assays to Diagnose Myocardial Infarction"..” Circulation 139, no. 4 (January 22, 2019): 564–65. https://doi.org/10.1161/CIRCULATIONAHA.118.038023.

PMID
30664370
Full Text

Thygesen, Kristian, Joseph S. Alpert, Allan S. Jaffe, Bernard R. Chaitman, Jeroen J. Bax, David A. Morrow, Harvey D. White, and Harvey D. ESC Scientific Document Group. “Fourth universal definition of myocardial infarction (2018)..” Eur Heart J 40, no. 3 (January 14, 2019): 237–69. https://doi.org/10.1093/eurheartj/ehy462.

PMID
30165617
Full Text

Todd, J. L., K. Durham, R. Overton, M. Neely, J. A. Belperio, M. Gulati, H. J. Huang, et al. “Peripheral Blood Proteomic Profiling to Distinguish Disease Biomarkers in the Multicenter IPF-PRO Registry Cohort.” In American Journal of Respiratory and Critical Care Medicine, Vol. 199. AMER THORACIC SOC, 2019.

Scholars@Duke

Navar, Ann Marie, Matthew T. Roe, Jennifer A. White, Christopher P. Cannon, Yuliya Lokhnygina, L Kristin Newby, Robert P. Giugliano, et al. “Medication Discontinuation in the IMPROVE-IT Trial..” Circ Cardiovasc Qual Outcomes 12, no. 1 (January 2019). https://doi.org/10.1161/CIRCOUTCOMES.118.005041.

PMID
30630361
Full Text

Pages