Cardiology

Laura Kristin Newby, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Duke Box 3213, Durham, NC 27710
Phone (919) 668-8805
Email address newby001@mc.duke.edu

Research Description

General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.

Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1990 - 1993
  • Medical Resident, Medicine, Duke University, 1987 - 1990
  • M.D., Indiana University at Indianapolis, 1987

Grants

Publications

Navar, AM, Roe, MT, White, JA, Cannon, CP, Lokhnygina, Y, Newby, LK, Giugliano, RP, Tershakovec, AM, Braunwald, E, Califf, RM, and Blazing, MA. "Medication Discontinuation in the IMPROVE-IT Trial." Circulation. Cardiovascular Quality and Outcomes 12, no. 1 (January 2019): e005041-null.

PMID
30630361
Full Text

McCord, J, Newby, LK, and deFilippi, CR. "Response by McCord et al to Letter Regarding Article, "Designing a Better Mousetrap: Reflections on the November 28, 2017, US Food and Drug Administration Meeting on Next-Generation "High-Sensitivity" Cardiac Troponin Assays to Diagnose Myocardial Infarction"." Circulation 139, no. 4 (January 2019): 564-565. (Letter)

PMID
30664370
Full Text

Berg, DD, Wiviott, SD, Braunwald, E, Guo, J, Im, K, Kashani, A, Gibson, CM, Cannon, CP, Morrow, DA, Bhatt, DL, Mega, JL, O'Donoghue, ML, Antman, EM, Newby, LK, Sabatine, MS, and Giugliano, RP. "Modes and timing of death in 66 252 patients with non-ST-segment elevation acute coronary syndromes enrolled in 14 TIMI trials." European Heart Journal 39, no. 42 (November 2018): 3810-3820.

PMID
30239711
Full Text

van Diepen, S, Tran, DT, Ezekowitz, JA, Zygun, DA, Katz, JN, Lopes, RD, Newby, LK, McAlister, FA, and Kaul, P. "The high cost of critical care unit over-utilization for patients with NSTE ACS." American Heart Journal 202 (August 2018): 84-88.

PMID
29906667
Full Text

Filgueiras Filho, NM, Feitosa Filho, GS, Solla, DJF, Argôlo, FC, Guimarães, PO, Paiva Filho, IDM, Carvalho, LGM, Teixeira, LS, Rios, MNDO, Câmara, SF, Novais, VO, Barbosa, LDS, Ballalai, CS, De Lúcia, CV, Granger, CB, Newby, LK, and Lopes, RD. "Implementation of a Regional Network for ST-Segment-Elevation Myocardial Infarction (STEMI) Care and 30-Day Mortality in a Low- to Middle-Income City in Brazil: Findings From Salvador's STEMI Registry (RESISST)." Journal of the American Heart Association 7, no. 14 (July 6, 2018).

PMID
29980522
Full Text

Rymer, JA, Tempelhof, MW, Clare, RM, Pieper, KS, Granger, CB, Van de Werf, F, Moliterno, DJ, Harrington, RA, White, HD, Armstrong, PW, Lopes, RD, Mahaffey, KW, and Newby, LK. "Discharge timing and outcomes after uncomplicated non-ST-segment elevation acute myocardial infarction." American Heart Journal 201 (July 2018): 103-110.

PMID
29910048
Full Text

McCord, J, Newby, LK, and deFilippi, CR. "Designing a Better Mousetrap: Reflections on the November 28, 2017, US Food and Drug Administration Meeting on Next-Generation "High-Sensitivity" Cardiac Troponin Assays to Diagnose Myocardial Infarction." Circulation 138, no. 3 (July 2018): 316-318.

PMID
30012704
Full Text

Newby, LK, and Lowenstern, A. "Implications of High-Sensitivity Troponin Testing: Learning From Those Who Came Before Us." Journal of the American College of Cardiology 71, no. 23 (June 2018): 2625-2627.

PMID
29880122
Full Text

Goldfarb, M, Bibas, L, Newby, LK, Henry, TD, Katz, J, van Diepen, S, and Cercek, B. "Systematic review and directors survey of quality indicators for the cardiovascular intensive care unit." International Journal of Cardiology 260 (June 2018): 219-225.

PMID
29514748
Full Text

Fanaroff, AC, Chen, AY, Thomas, LE, Pieper, KS, Garratt, KN, Peterson, ED, Newby, LK, de Lemos, JA, Kosiborod, MN, Amsterdam, EA, and Wang, TY. "Risk Score to Predict Need for Intensive Care in Initially Hemodynamically Stable Adults With Non-ST-Segment-Elevation Myocardial Infarction." Journal of the American Heart Association 7, no. 11 (May 25, 2018).

PMID
29802146
Full Text

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