General Internal Medicine

Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Executive Core Faculty Member, Duke-Margolis Center for Health Policy
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Lesley H. Curtis is Professor and Chair of the Department of Population Health Sciences in the Duke School of Medicine.  A health services researcher by training, Dr. Curtis is an expert in the use of Medicare claims data for health services and clinical outcomes research, and a leader in national data quality efforts. Dr. Curtis serves as co-PI of the FDA’s Sentinel Innovation Center, Co-Investigator of the Data Core for the FDA’s Sentinel Initiative to monitor the safety of FDA-regulated medical products, and Chair of the Data Quality Subcommittee for the National Evaluation System for health Technology (NEST) Coordinating Center that generates real-world evidence for health technology and medical devices. She serves as co-Investigator of the coordinating center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized network infrastructure that leverages health systems and electronic health record data for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Grants

Publications

Lentz, Trevor A., Lesley H. Curtis, Frank W. Rockhold, David Martin, Tomas L. G. Andersson, Carolyn Arias, Jesse A. Berlin, et al. “Designing, Conducting, Monitoring, and Analyzing Data from Pragmatic Randomized Clinical Trials: Proceedings from a Multi-stakeholder Think Tank Meeting.” Ther Innov Regul Sci, June 8, 2020. https://doi.org/10.1007/s43441-020-00175-7.

PMID
32514736
Full Text

Ahmad, Faraz S., Iben M. Ricket, Bradley G. Hammill, Lisa Eskenazi, Holly R. Robertson, Lesley H. Curtis, Cecilia D. Dobi, et al. “Computable Phenotype Implementation for a National, Multicenter Pragmatic Clinical Trial: Lessons Learned From ADAPTABLE.” Circ Cardiovasc Qual Outcomes 13, no. 6 (June 2020): e006292. https://doi.org/10.1161/CIRCOUTCOMES.119.006292.

PMID
32466729
Full Text

Gewandter, Jennifer S., Amber S. Kleckner, James H. Marshall, Jeffrey S. Brown, Lesley H. Curtis, Javier Bautista, Robert H. Dworkin, et al. “Chemotherapy-induced peripheral neuropathy (CIPN) and its treatment: an NIH Collaboratory study of claims data.” Support Care Cancer 28, no. 6 (June 2020): 2553–62. https://doi.org/10.1007/s00520-019-05063-x.

PMID
31494735
Full Text

Kelly, Jacob P., Nicholas G. Ballew, Li Lin, Bradley G. Hammill, Timothy M. Stivland, Paul W. Jones, Lesley H. Curtis, Adrian F. Hernandez, Melissa A. Greiner, and Brett D. Atwater. “Association of Implantable Device Measured Physical Activity With Hospitalization for Heart Failure.” Jacc Heart Fail 8, no. 4 (April 2020): 280–88. https://doi.org/10.1016/j.jchf.2019.10.009.

PMID
32035894
Full Text

Maciejewski, Matthew L., Bradley G. Hammill, Laura Ding, Lesley H. Curtis, Elizabeth A. Bayliss, Abby F. Hoffman, and Virginia Wang. “Care continuity impacts medicare expenditures of older adults: Fact or fiction?” Healthc (Amst) 8, no. 1 (March 2020): 100364. https://doi.org/10.1016/j.hjdsi.2019.05.004.

PMID
31155480
Full Text

Marsolo, Keith A., Jeffrey S. Brown, Adrian F. Hernandez, Bradley G. Hammill, Sudha R. Raman, Beth Syat, Richard Platt, and Lesley H. Curtis. “Considerations for using distributed research networks to conduct aspects of randomized trials.” Contemp Clin Trials Commun 17 (March 2020): 100515. https://doi.org/10.1016/j.conctc.2019.100515.

PMID
31956724
Full Text

Brennan, J Matthew, Lisa Wruck, Michael J. Pencina, Robert M. Clare, Renato D. Lopes, John H. Alexander, Sean O’Brien, et al. “Claims-based cardiovascular outcome identification for clinical research: Results from 7 large randomized cardiovascular clinical trials.” Am Heart J 218 (December 2019): 110–22. https://doi.org/10.1016/j.ahj.2019.09.002.

PMID
31726314
Full Text

Steinberg, Benjamin A., Nicholas G. Ballew, Melissa A. Greiner, Steven J. Lippmann, Lesley H. Curtis, Emily C. O’Brien, Manesh R. Patel, and Jonathan P. Piccini. “Ischemic and Bleeding Outcomes in Patients With Atrial Fibrillation and Contraindications to Oral Anticoagulation.” Jacc Clin Electrophysiol 5, no. 12 (December 2019): 1384–92. https://doi.org/10.1016/j.jacep.2019.07.011.

PMID
31857036
Full Text

Kusumoto, Fred M., Mark H. Schoenfeld, Coletta Barrett, James R. Edgerton, Kenneth A. Ellenbogen, Michael R. Gold, Nora F. Goldschlager, et al. “2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society.” J Am Coll Cardiol 74, no. 7 (August 20, 2019): 932–87. https://doi.org/10.1016/j.jacc.2018.10.043.

PMID
30412710
Full Text

Pages