General Internal Medicine

Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Dr. Curtis is a health services researcher who oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. 

Dr Curtis directs the Center for Pragmatic Health Systems Research at the Duke Clinical Research Institute and leads the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Grants

Publications

Cooper, Lauren B., Steven J. Lippmann, Julia R. DiBello, Boris Gorsh, Lesley H. Curtis, Vanja Sikirica, Adrian F. Hernandez, et al. “The Burden of Congestion in Patients Hospitalized With Acute Decompensated Heart Failure..” Am J Cardiol 124, no. 4 (August 15, 2019): 545–53. https://doi.org/10.1016/j.amjcard.2019.05.030.

PMID
31208702
Full Text

Curtis, Lesley H., Laura M. Dember, Miguel A. Vazquez, David Murray, Lynn DeBar, Karen L. Staman, Edward Septimus, et al. “Addressing guideline and policy changes during pragmatic clinical trials..” Clin Trials 16, no. 4 (August 2019): 431–37. https://doi.org/10.1177/1740774519845682.

PMID
31084378
Full Text

January, Craig T., L Samuel Wann, Hugh Calkins, Lin Y. Chen, Joaquin E. Cigarroa, Joseph C. Cleveland, Patrick T. Ellinor, et al. “2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society..” J Am Coll Cardiol 74, no. 1 (July 9, 2019): 104–32. https://doi.org/10.1016/j.jacc.2019.01.011.

PMID
30703431
Full Text

Wilson, Peter W. F., Tamar S. Polonsky, Michael D. Miedema, Amit Khera, Andrzej S. Kosinski, and Jeffrey T. Kuvin. “Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Am Coll Cardiol 73, no. 24 (June 25, 2019): 3210–27. https://doi.org/10.1016/j.jacc.2018.11.004.

PMID
30423394
Full Text

Grundy, Scott M., Neil J. Stone, Alison L. Bailey, Craig Beam, Kim K. Birtcher, Roger S. Blumenthal, Lynne T. Braun, et al. “2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Am Coll Cardiol 73, no. 24 (June 25, 2019): 3168–3209. https://doi.org/10.1016/j.jacc.2018.11.002.

PMID
30423391
Full Text

Grundy, Scott M., Neil J. Stone, Alison L. Bailey, Craig Beam, Kim K. Birtcher, Roger S. Blumenthal, Lynne T. Braun, et al. “2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Am Coll Cardiol 73, no. 24 (June 25, 2019): e285–350. https://doi.org/10.1016/j.jacc.2018.11.003.

PMID
30423393
Full Text

Pumill, Christopher A., Christopher G. Bush, Melissa A. Greiner, Michael E. Hall, Shannon M. Dunlay, Adolfo Correa, Lesley H. Curtis, et al. “Neck circumference and cardiovascular outcomes: Insights from the Jackson Heart Study..” Am Heart J 212 (June 2019): 72–79. https://doi.org/10.1016/j.ahj.2019.03.001.

PMID
30954832
Full Text

Maciejewski, Matthew L., Bradley G. Hammill, Laura Ding, Lesley H. Curtis, Elizabeth A. Bayliss, Abby F. Hoffman, and Virginia Wang. “Care continuity impacts medicare expenditures of older adults: Fact or fiction?.” Healthc (Amst), May 30, 2019. https://doi.org/10.1016/j.hjdsi.2019.05.004.

PMID
31155480
Full Text

Lowenstern, Angela, Steven J. Lippmann, J Matthew Brennan, Tracy Y. Wang, Lesley H. Curtis, Ted Feldman, Donald D. Glower, Bradley G. Hammill, and Sreekanth Vemulapalli. “Use of Medicare Claims to Identify Adverse Clinical Outcomes After Mitral Valve Repair..” Circ Cardiovasc Interv 12, no. 5 (May 2019). https://doi.org/10.1161/CIRCINTERVENTIONS.118.007451.

PMID
31084236
Full Text

Gourevitch, Marc N., Lesley H. Curtis, Maureen S. Durkin, Angela Fagerlin, Annetine C. Gelijns, Richard Platt, Belinda M. Reininger, Judith Wylie-Rosett, Katherine Jones, and William M. Tierney. “The Emergence of Population Health in US Academic Medicine: A Qualitative Assessment..” Jama Netw Open 2, no. 4 (April 5, 2019). https://doi.org/10.1001/jamanetworkopen.2019.2200.

PMID
30977857
Full Text

Pages