Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Executive Core Faculty Member, Duke-Margolis Center for Health Policy
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Lesley H. Curtis is Professor and Chair of the Department of Population Health Sciences in the Duke School of Medicine.  A health services researcher by training, Dr. Curtis is an expert in the use of Medicare claims data for health services and clinical outcomes research, and a leader in national data quality efforts. Dr. Curtis serves as co-PI of the FDA’s Sentinel Innovation Center, Co-Investigator of the Data Core for the FDA’s Sentinel Initiative to monitor the safety of FDA-regulated medical products, and Chair of the Data Quality Subcommittee for the National Evaluation System for health Technology (NEST) Coordinating Center that generates real-world evidence for health technology and medical devices. She serves as co-Investigator of the coordinating center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized network infrastructure that leverages health systems and electronic health record data for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Kelsey, Michelle D., Bray Patrick-Lake, Raolat Abdulai, Uli C. Broedl, Adam Brown, Elizabeth Cohn, Lesley H. Curtis, et al. “Inclusion and diversity in clinical trials: Actionable steps to drive lasting change.” Contemp Clin Trials 116 (May 2022): 106740. https://doi.org/10.1016/j.cct.2022.106740.

PMID
35364292
Full Text

Raman, Sudha R., Emily C. O’Brien, Bradley G. Hammill, Adam J. Nelson, Laura J. Fish, Lesley H. Curtis, and Keith Marsolo. “Evaluating fitness-for-use of electronic health records in pragmatic clinical trials: reported practices and recommendations.” J Am Med Inform Assoc 29, no. 5 (April 13, 2022): 798–804. https://doi.org/10.1093/jamia/ocac004.

PMID
35171985
Full Text

Weissler, E Hope, Cassie B. Ford, Dennis I. Narcisse, Steven J. Lippmann, Michelle M. Smerek, Melissa A. Greiner, N Chantelle Hardy, et al. “Clinician Specialty, Access to Care, and Outcomes Among Patients with Peripheral Artery Disease.” Am J Med 135, no. 2 (February 2022): 219–27. https://doi.org/10.1016/j.amjmed.2021.08.025.

PMID
34627781
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Desai, Rishi J., Michael E. Matheny, Kevin Johnson, Keith Marsolo, Lesley H. Curtis, Jennifer C. Nelson, Patrick J. Heagerty, et al. “Broadening the reach of the FDA Sentinel system: A roadmap for integrating electronic health record data in a causal analysis framework.” Npj Digit Med 4, no. 1 (December 20, 2021): 170. https://doi.org/10.1038/s41746-021-00542-0.

PMID
34931012
Full Text

Bhavsar, Nrupen A., Clemontina A. Davenport, Lexie Zidanyue Yang, Sarah Peskoe, Julia J. Scialla, Rasheeda K. Hall, Crystal C. Tyson, et al. “Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.” Bmc Nephrol 22, no. 1 (November 11, 2021): 375. https://doi.org/10.1186/s12882-021-02594-6.

PMID
34763649
Full Text

Weissler, E Hope, Tristan Naumann, Tomas Andersson, Rajesh Ranganath, Olivier Elemento, Yuan Luo, Daniel F. Freitag, et al. “Correction to: The role of machine learning in clinical research: transforming the future of evidence generation.” Trials 22, no. 1 (September 6, 2021): 593. https://doi.org/10.1186/s13063-021-05571-4.

PMID
34488840
Full Text

Narcisse, Dennis I., Cassie B. Ford, E Hope Weissler, Steven J. Lippmann, Michelle M. Smerek, Melissa A. Greiner, N Chantelle Hardy, et al. “The association of healthcare disparities and patient-specific factors on clinical outcomes in peripheral artery disease.” Am Heart J 239 (September 2021): 135–46. https://doi.org/10.1016/j.ahj.2021.05.014.

PMID
34052213
Full Text

Curtis, Lesley H., Molly N. Hoffman, Robert M. Califf, and Bradley G. Hammill. “Life expectancy and voting patterns in the 2020 U.S. presidential election.” Ssm Popul Health 15 (September 2021): 100840. https://doi.org/10.1016/j.ssmph.2021.100840.

PMID
34169139
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Greene, Stephen J., Sujung Choi, Steven J. Lippmann, Robert J. Mentz, Melissa A. Greiner, N Chantelle Hardy, Bradley G. Hammill, et al. “Clinical Effectiveness of Sacubitril/Valsartan Among Patients Hospitalized for Heart Failure With Reduced Ejection Fraction.” J Am Heart Assoc 10, no. 16 (August 17, 2021): e021459. https://doi.org/10.1161/JAHA.121.021459.

PMID
34350772
Full Text

Weissler, E Hope, Tristan Naumann, Tomas Andersson, Rajesh Ranganath, Olivier Elemento, Yuan Luo, Daniel F. Freitag, et al. “The role of machine learning in clinical research: transforming the future of evidence generation.” Trials 22, no. 1 (August 16, 2021): 537. https://doi.org/10.1186/s13063-021-05489-x.

PMID
34399832
Full Text

Pages