Lesley H. Curtis, PhD

Professor in Population Health Sciences
Interim Executive Director, Duke Clinical Research Institute
Professor in Medicine
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Executive Core Faculty Member, Duke-Margolis Center for Health Policy
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Lesley H. Curtis is Professor and Chair of the Department of Population Health Sciences in the Duke School of Medicine.  A health services researcher by training, Dr. Curtis is an expert in the use of Medicare claims data for health services and clinical outcomes research, and a leader in national data quality efforts. Dr. Curtis serves as co-PI of the FDA’s Sentinel Innovation Center, Co-Investigator of the Data Core for the FDA’s Sentinel Initiative to monitor the safety of FDA-regulated medical products, and Chair of the Data Quality Subcommittee for the National Evaluation System for health Technology (NEST) Coordinating Center that generates real-world evidence for health technology and medical devices. She serves as co-Investigator of the coordinating center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized network infrastructure that leverages health systems and electronic health record data for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Curtis, Lesley H., Molly N. Hoffman, Robert M. Califf, and Bradley G. Hammill. “Life expectancy and voting patterns in the 2020 U.S. presidential election.” Ssm Popul Health 15 (September 2021): 100840. https://doi.org/10.1016/j.ssmph.2021.100840.

PMID
34169139
Full Text

Narcisse, Dennis I., Cassie B. Ford, E Hope Weissler, Steven J. Lippmann, Michelle M. Smerek, Melissa A. Greiner, N Chantelle Hardy, et al. “The association of healthcare disparities and patient-specific factors on clinical outcomes in peripheral artery disease.” Am Heart J 239 (September 2021): 135–46. https://doi.org/10.1016/j.ahj.2021.05.014.

PMID
34052213
Full Text

Tuzzio, Leah, Catherine M. Meyers, Laura M. Dember, Corita R. Grudzen, Edward R. Melnick, Karen L. Staman, Susan S. Huang, et al. “Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies.” Healthc (Amst) 8 Suppl 1 (June 2021): 100432. https://doi.org/10.1016/j.hjdsi.2020.100432.

PMID
34175091
Full Text

Jones, W Schuyler, Hillary Mulder, Lisa M. Wruck, Michael J. Pencina, Sunil Kripalani, Daniel Muñoz, David L. Crenshaw, et al. “Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease.” N Engl J Med 384, no. 21 (May 27, 2021): 1981–90. https://doi.org/10.1056/NEJMoa2102137.

PMID
33999548
Full Text

Fuller, Candace C., Vinod E. Nambudiri, Caren Spencer-Smith, Lesley H. Curtis, Mayura Shinde, Austin Cosgrove, Margaret Johnson, et al. “Medical chart validation of inpatient diagnosis codes for transfusion-related acute lung injury 2013-2015.” Transfusion 61, no. 3 (March 2021): 754–66. https://doi.org/10.1111/trf.16251.

PMID
33506519
Full Text

Califf, Robert M., Lesley H. Curtis, Robert A. Harrington, Adrian F. Hernandez, and Eric D. Peterson. “Generating evidence for therapeutic effects: the need for well-conducted randomized trials.” J Clin Invest 131, no. 2 (January 19, 2021). https://doi.org/10.1172/JCI146391.

PMID
33270604
Full Text

Lentz, Trevor A., Lesley H. Curtis, Frank W. Rockhold, David Martin, Tomas L. G. Andersson, Carolyn Arias, Jesse A. Berlin, et al. “Designing, Conducting, Monitoring, and Analyzing Data from Pragmatic Randomized Clinical Trials: Proceedings from a Multi-stakeholder Think Tank Meeting.” Ther Innov Regul Sci 54, no. 6 (November 2020): 1477–88. https://doi.org/10.1007/s43441-020-00175-7.

PMID
32514736
Full Text

Stevens, Laura M., Bobak J. Mortazavi, Rahul C. Deo, Lesley Curtis, and David P. Kao. “Recommendations for Reporting Machine Learning Analyses in Clinical Research.” Circulation. Cardiovascular Quality and Outcomes 13, no. 10 (October 14, 2020): e006556. https://doi.org/10.1161/circoutcomes.120.006556.

PMID
33079589
Full Text

Bae, Jonathan A., Lesley H. Curtis, and Adrian F. Hernandez. “National Hospital Quality Rankings: Improving the Value of Information in Hospital Rating Systems.” Jama 324, no. 9 (September 1, 2020): 839–40. https://doi.org/10.1001/jama.2020.11165.

PMID
32730574
Full Text

Bennett, Antonia V., Mattias Jonsson, Ronald C. Chen, Sana M. Al-Khatib, Kevin P. Weinfurt, and Lesley H. Curtis. “Applying patient-reported outcome methodology to capture patient-reported health data: Report from an NIH Collaboratory roundtable.” Healthc (Amst) 8, no. 3 (September 2020): 100442. https://doi.org/10.1016/j.hjdsi.2020.100442.

PMID
32919581
Full Text

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