General Internal Medicine

Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Executive Core Faculty Member, Duke-Margolis Center for Health Policy
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Lesley H. Curtis is Professor and Chair of the Department of Population Health Sciences in the Duke School of Medicine.  A health services researcher by training, Dr. Curtis is an expert in the use of Medicare claims data for health services and clinical outcomes research, and a leader in national data quality efforts. Dr. Curtis serves as co-PI of the FDA’s Sentinel Innovation Center, Co-Investigator of the Data Core for the FDA’s Sentinel Initiative to monitor the safety of FDA-regulated medical products, and Chair of the Data Quality Subcommittee for the National Evaluation System for health Technology (NEST) Coordinating Center that generates real-world evidence for health technology and medical devices. She serves as co-Investigator of the coordinating center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized network infrastructure that leverages health systems and electronic health record data for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Grants

Publications

Califf, Robert M., Lesley H. Curtis, Robert A. Harrington, Adrian F. Hernandez, and Eric D. Peterson. “Generating evidence for therapeutic effects: the need for well-conducted randomized trials.” J Clin Invest 131, no. 2 (January 19, 2021). https://doi.org/10.1172/JCI146391.

PMID
33270604
Full Text

Lentz, Trevor A., Lesley H. Curtis, Frank W. Rockhold, David Martin, Tomas L. G. Andersson, Carolyn Arias, Jesse A. Berlin, et al. “Designing, Conducting, Monitoring, and Analyzing Data from Pragmatic Randomized Clinical Trials: Proceedings from a Multi-stakeholder Think Tank Meeting.” Ther Innov Regul Sci 54, no. 6 (November 2020): 1477–88. https://doi.org/10.1007/s43441-020-00175-7.

PMID
32514736
Full Text

Stevens, Laura M., Bobak J. Mortazavi, Rahul C. Deo, Lesley Curtis, and David P. Kao. “Recommendations for Reporting Machine Learning Analyses in Clinical Research.” Circulation. Cardiovascular Quality and Outcomes 13, no. 10 (October 14, 2020): e006556. https://doi.org/10.1161/circoutcomes.120.006556.

PMID
33079589
Full Text

Bae, Jonathan A., Lesley H. Curtis, and Adrian F. Hernandez. “National Hospital Quality Rankings: Improving the Value of Information in Hospital Rating Systems.” Jama 324, no. 9 (September 1, 2020): 839–40. https://doi.org/10.1001/jama.2020.11165.

PMID
32730574
Full Text

Bennett, Antonia V., Mattias Jonsson, Ronald C. Chen, Sana M. Al-Khatib, Kevin P. Weinfurt, and Lesley H. Curtis. “Applying patient-reported outcome methodology to capture patient-reported health data: Report from an NIH Collaboratory roundtable.” Healthc (Amst) 8, no. 3 (September 2020): 100442. https://doi.org/10.1016/j.hjdsi.2020.100442.

PMID
32919581
Full Text

Weissler, Elizabeth Hope, Steven J. Lippmann, Michelle M. Smerek, Rachael A. Ward, Aman Kansal, Adam Brock, Robert C. Sullivan, et al. “Model-Based Algorithms for Detecting Peripheral Artery Disease Using Administrative Data From an Electronic Health Record Data System: Algorithm Development Study.” Jmir Med Inform 8, no. 8 (August 19, 2020): e18542. https://doi.org/10.2196/18542.

PMID
32663152
Full Text

Gewandter, Jennifer S., Amber S. Kleckner, James H. Marshall, Jeffrey S. Brown, Lesley H. Curtis, Javier Bautista, Robert H. Dworkin, et al. “Chemotherapy-induced peripheral neuropathy (CIPN) and its treatment: an NIH Collaboratory study of claims data.” Support Care Cancer 28, no. 6 (June 2020): 2553–62. https://doi.org/10.1007/s00520-019-05063-x.

PMID
31494735
Full Text

Ahmad, Faraz S., Iben M. Ricket, Bradley G. Hammill, Lisa Eskenazi, Holly R. Robertson, Lesley H. Curtis, Cecilia D. Dobi, et al. “Computable Phenotype Implementation for a National, Multicenter Pragmatic Clinical Trial: Lessons Learned From ADAPTABLE.” Circ Cardiovasc Qual Outcomes 13, no. 6 (June 2020): e006292. https://doi.org/10.1161/CIRCOUTCOMES.119.006292.

PMID
32466729
Full Text

Kelly, Jacob P., Nicholas G. Ballew, Li Lin, Bradley G. Hammill, Timothy M. Stivland, Paul W. Jones, Lesley H. Curtis, Adrian F. Hernandez, Melissa A. Greiner, and Brett D. Atwater. “Association of Implantable Device Measured Physical Activity With Hospitalization for Heart Failure.” Jacc Heart Fail 8, no. 4 (April 2020): 280–88. https://doi.org/10.1016/j.jchf.2019.10.009.

PMID
32035894
Full Text

Pages