Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail 2200 West Main Street, Suite 720-A, Erwin Square Building, Durham, NC 27705
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Dr. Curtis is a health services researcher who oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. 

Dr Curtis directs the Center for Pragmatic Health Systems Research at the Duke Clinical Research Institute and leads the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Page, RL, Joglar, JA, Caldwell, MA, Calkins, H, Conti, JB, Deal, BJ, Estes, NAM, Field, ME, Goldberger, ZD, Hammill, SC, Indik, JH, Lindsay, BD, Olshansky, B, Russo, AM, Shen, W-K, Tracy, CM, Al-Khatib, SM, and Evidence Review Committee Chair‡, . "2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Circulation 133, no. 14 (April 2016): e471-e505.

PMID
26399662
Full Text

Al-Khatib, SM, Arshad, A, Balk, EM, Das, SR, Hsu, JC, Joglar, JA, and Page, RL. "Risk Stratification for Arrhythmic Events in Patients With Asymptomatic Pre-Excitation: A Systematic Review for the 2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Circulation 133, no. 14 (April 2016): e575-e586. (Review)

PMID
26399661
Full Text

Halperin, JL, Levine, GN, Al-Khatib, SM, Birtcher, KK, Bozkurt, B, Brindis, RG, Cigarroa, JE, Curtis, LH, Fleisher, LA, Gentile, F, Gidding, S, Hlatky, MA, Ikonomidis, J, Joglar, J, Pressler, SJ, and Wijeysundera, DN. "Further Evolution of the ACC/AHA Clinical Practice Guideline Recommendation Classification System: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines." Journal of the American College of Cardiology 67, no. 13 (April 2016): 1572-1574.

PMID
26409257
Full Text

Pasquali, SK, Jacobs, JP, Farber, GK, Bertoch, D, Blume, ED, Burns, KM, Campbell, R, Chang, AC, Chung, WK, Riehle-Colarusso, T, Curtis, LH, Forrest, CB, Gaynor, WJ, Gaies, MG, Go, AS, Henchey, P, Martin, GR, Pearson, G, Pemberton, VL, Schwartz, SM, Vincent, R, and Kaltman, JR. "Report of the National Heart, Lung, and Blood Institute Working Group: An Integrated Network for Congenital Heart Disease Research." Circulation 133, no. 14 (April 2016): 1410-1418.

PMID
27045129
Full Text

Hiratzka, LF, Creager, MA, Isselbacher, EM, Svensson, LG, Nishimura, RA, Bonow, RO, Guyton, RA, and Sundt, TM. "Surgery for aortic dilatation in patients with bicuspid aortic valves." The Journal of Thoracic and Cardiovascular Surgery 151, no. 4 (April 2016): 959-966.

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Chan, PS, McNally, B, Nallamothu, BK, Tang, F, Hammill, BG, Spertus, JA, and Curtis, LH. "Long-Term Outcomes Among Elderly Survivors of Out-of-Hospital Cardiac Arrest." Journal of the American Heart Association 5, no. 3 (March 15, 2016): e002924-null.

PMID
27068632
Full Text

Mentz, RJ, Hernandez, AF, Berdan, LG, Rorick, T, O'Brien, EC, Ibarra, JC, Curtis, LH, and Peterson, ED. "Good Clinical Practice Guidance and Pragmatic Clinical Trials: Balancing the Best of Both Worlds." Circulation 133, no. 9 (March 2016): 872-880. (Review)

PMID
26927005
Full Text

Levine, GN, Bates, ER, Blankenship, JC, Bailey, SR, Bittl, JA, Cercek, B, Chambers, CE, Ellis, SG, Guyton, RA, Hollenberg, SM, Khot, UN, Lange, RA, Mauri, L, Mehran, R, Moussa, ID, Mukherjee, D, Ting, HH, O'Gara, PT, Kushner, FG, Ascheim, DD, Brindis, RG, Casey, DE, Chung, MK, de Lemos, JA, Diercks, DB, Fang, JC, Franklin, BA, Granger, CB, Krumholz, HM, Linderbaum, JA, Morrow, DA, Newby, LK, Ornato, JP, Ou, N, Radford, MJ, Tamis-Holland, JE, Tommaso, CL, Tracy, CM, Woo, YJ, and Zhao, DX. "2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction." Journal of the American College of Cardiology 67, no. 10 (March 2016): 1235-1250. (Review)

PMID
26498666
Full Text

Levine, GN, Bates, ER, Blankenship, JC, Bailey, SR, Bittl, JA, Cercek, B, Chambers, CE, Ellis, SG, Guyton, RA, Hollenberg, SM, Khot, UN, Lange, RA, Mauri, L, Mehran, R, Moussa, ID, Mukherjee, D, Ting, HH, O'Gara, PT, Kushner, FG, Ascheim, DD, Brindis, RG, Casey, DE, Chung, MK, de Lemos, JA, Diercks, DB, Fang, JC, Franklin, BA, Granger, CB, Krumholz, HM, Linderbaum, JA, Morrow, DA, Newby, LK, Ornato, JP, Ou, N, Radford, MJ, Tamis-Holland, JE, Tommaso, CL, Tracy, CM, Woo, YJ, and Zhao, DX. "2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions." Circulation 133, no. 11 (March 2016): 1135-1147.

PMID
26490017
Full Text

Dinan, MA, Mi, X, Reed, SD, Lyman, GH, and Curtis, LH. "Chemotherapy costs associated with receipt of the adoption of oncotype DX in early-stage breast cancer within the SEER-Medicare population." March 2016.

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