Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Dr. Curtis is a health services researcher who oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. 

Dr Curtis directs the Center for Pragmatic Health Systems Research at the Duke Clinical Research Institute and leads the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Mi, Xiaojuan, Bradley G. Hammill, Lesley H. Curtis, Edward Chia-Cheng Lai, and Soko Setoguchi. “Use of the landmark method to address immortal person-time bias in comparative effectiveness research: a simulation study..” Stat Med 35, no. 26 (November 20, 2016): 4824–36. https://doi.org/10.1002/sim.7019.

PMID
27350312
Full Text

Levine, Glenn N., Eric R. Bates, John A. Bittl, Ralph G. Brindis, Stephan D. Fihn, Lee A. Fleisher, Christopher B. Granger, et al. “2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Thorac Cardiovasc Surg 152, no. 5 (November 2016): 1243–75. https://doi.org/10.1016/j.jtcvs.2016.07.044.

PMID
27751237
Full Text

Maciejewski, Matthew L., Xiaojuan Mi, Lesley H. Curtis, Judy Ng, Samuel C. Haffer, and Bradley G. Hammill. “Few Disparities in Baseline Laboratory Testing After the Diuretic or Digoxin Initiation by Medicare Fee-For-Service Beneficiaries..” Circ Cardiovasc Qual Outcomes 9, no. 6 (November 2016): 714–22. https://doi.org/10.1161/CIRCOUTCOMES.116.003052.

PMID
27756796
Full Text

Jones, W Schuyler, Matthew T. Roe, Elliott M. Antman, Mark J. Pletcher, Robert A. Harrington, Russell L. Rothman, William J. Oetgen, et al. “The Changing Landscape of Randomized Clinical Trials in Cardiovascular Disease..” J Am Coll Cardiol 68, no. 17 (October 25, 2016): 1898–1907. https://doi.org/10.1016/j.jacc.2016.07.781.

PMID
27765193
Full Text

Chan, Paul S., Robert A. Berg, Yuanyuan Tang, Lesley H. Curtis, John A. Spertus, and John A. American Heart Association’s Get With the Guidelines–Resuscitation Investigators. “Association Between Therapeutic Hypothermia and Survival After In-Hospital Cardiac Arrest..” Jama 316, no. 13 (October 4, 2016): 1375–82. https://doi.org/10.1001/jama.2016.14380.

PMID
27701659
Full Text

Garg, P. K., W. J. H. Koh, J. A. Delaney, E. A. Halm, C. H. Hirsch, W. T. Longstreth, K. J. Mukamal, A. Kucharska-Newton, J. F. Polak, and L. Curtis. “Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study.” Cerebrovascular Diseases Extra 6, no. 3 (September 7, 2016): 129–39. https://doi.org/10.1159/000452426.

Full Text

Levine, Glenn N., Eric R. Bates, John A. Bittl, Ralph G. Brindis, Stephan D. Fihn, Lee A. Fleisher, Christopher B. Granger, et al. “2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Am Coll Cardiol 68, no. 10 (September 6, 2016): 1082–1115. https://doi.org/10.1016/j.jacc.2016.03.513.

PMID
27036918
Full Text

Bittl, John A., Usman Baber, Steven M. Bradley, and Duminda N. Wijeysundera. “Duration of Dual Antiplatelet Therapy: A Systematic Review for the 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Am Coll Cardiol 68, no. 10 (September 6, 2016): 1116–39. https://doi.org/10.1016/j.jacc.2016.03.512.

PMID
27036919
Full Text

Khazanie, Prateeti, Bradley G. Hammill, Chetan B. Patel, Michael S. Kiernan, Lauren B. Cooper, Suzanne V. Arnold, Timothy J. Fendler, John A. Spertus, Lesley H. Curtis, and Adrian F. Hernandez. “Use of Heart Failure Medical Therapies Among Patients With Left Ventricular Assist Devices: Insights From INTERMACS..” J Card Fail 22, no. 9 (September 2016): 672–79. https://doi.org/10.1016/j.cardfail.2016.02.004.

PMID
26892975
Full Text

Maciejewski, Matthew L., Bradley G. Hammill, Laura G. Qualls, Susan N. Hastings, Virginia Wang, and Lesley H. Curtis. “Appropriate baseline laboratory testing following ACEI or ARB initiation by Medicare FFS beneficiaries..” Pharmacoepidemiol Drug Saf 25, no. 9 (September 2016): 1015–22. https://doi.org/10.1002/pds.3994.

PMID
26991354
Full Text

Pages