Manesh Raman Patel, MD

Professor of Medicine
Chief, Division of Cardiology
Chief, Division of Clinical Pharmacology
Core Faculty in Innovation & Entrepreneurship
Member in the Duke Clinical Research Institute
Campus mail 2301 Erwin Road, Hafs Building, Room 8695, Durham, NC 27710
Phone (919) 681-4441
Email address

Manesh Patel is the Chief of the Division of Cardiology and the Division of Clinical Pharmacology.  His clinical interests include diagnostic and interventional coronary angiography, peripheral angiography and endovascular intervention.  His is involved in several clinical trials involving patients with cardiovascular disease and in cardiac imaging.  He is also the Chair of the American College of Cardiology Task Force for Appropriate Use Criteria for Cardiovascular Procedures and is Chair of the American Heart Association Diagnostic and Interventional Cath Committee.

Patel's interest in cardiac imaging, quality of care, cardiac devices is also evident in his research.  His integration of these efforts into his roles at Duke was recognized in 2010 when he received the prestigious Duke Cardiology Fellowship Mentor Award.   In 2011, Dr. Patel was named the endowed John Bush Simpson Assistant Professor of Cardiology.  In 2013, Dr. Patel received the Robert M. Califf Faculty clinical research Award.

Currently, Dr. Patel is leading an effort to redesign the delivery of care to patients undergoing invasive catheterization procedures in the health system with a specific aim of measure and providing individualized, patient centered, innovative, and efficient care.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 2002 - 2006
  • Fellow in Cardiology, Medicine, Duke University, 2000 - 2001
  • Medical Resident, Medicine, Duke University, 1997 - 2000
  • M.D., Emory University, 1997


Smolderen, KG, Gosch, K, Patel, M, Jones, WS, Hirsch, AT, Beltrame, J, Fitridge, R, Shishehbor, MH, Denollet, J, Vriens, P, Heyligers, J, Stone MEd, N, Aronow, H, Abbott, JD, Labrosciano, C, Tutein-Nolthenius, R, and A Spertus, J. "PORTRAIT (Patient-Centered Outcomes Related to Treatment Practices in Peripheral Arterial Disease: Investigating Trajectories): Overview of Design and Rationale of an International Prospective Peripheral Arterial Disease Study." Circulation. Cardiovascular Quality and Outcomes 11, no. 2 (February 2018): e003860-null. (Review)

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Bonow, RO, Brown, AS, Gillam, LD, Kapadia, SR, Kavinsky, CJ, Lindman, BR, Mack, MJ, Thourani, VH, Dehmer, GJ, Beaver, TM, Bradley, SM, Carabello, BA, Desai, MY, George, I, Green, P, Holmes, DR, Johnston, D, Leipsic, J, Mick, SL, Passeri, JJ, Piana, RN, Reichek, N, Ruiz, CE, Taub, CC, Thomas, JD, Turi, ZG, Doherty, JU, Bailey, SR, Bhave, NM, Daugherty, SL, Dean, LS, Duvernoy, CS, Hendel, RC, Kramer, CM, Lindsay, BD, Manning, WJ, Mehrotra, P, Patel, MR, Sachdeva, R, Wann, LS, and Winchester, DE et al. "ACC/AATS/AHA/ASE/EACTS/HVS/SCA/SCAI/SCCT/SCMR/STS 2017 Appropriate use criteria for the treatment of patients with severe aortic stenosis: A report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Valve Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons." European Journal of Cardio-thoracic Surgery 53, no. 2 (February 1, 2018): 306-308.

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Wang, WT, Hellkamp, A, Doll, JA, Thomas, L, Navar, AM, Fonarow, GC, Julien, HM, Peterson, ED, and Wang, TY. "Lipid Testing and Statin Dosing After Acute Myocardial Infarction." Journal of the American Heart Association 7, no. 3 (January 25, 2018).

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Jones, WS, and Patel, MR. "Antithrombotic Therapy in Peripheral Artery Disease Generating and Translating Evidence Into Practice." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 71, no. 3 (January 23, 2018): 353-362.


Ward, R, Long, C, Patel, MR, and Jones, WS. "Antithrombotic therapy in peripheral artery disease: A review of the EUCLID trial results and current ongoing trials." Clinical Cardiology 41, no. 1 (January 22, 2018): 137-143. (Review)

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Chen, ST, and Patel, MR. "Comparison of Anticoagulant Therapy for Atrial Fibrillation - Novel Oral Anticoagulants Versus Vitamin K Antagonists." Progress in Cardiovascular Diseases 60, no. 4-5 (January 13, 2018): 514-523. (Review)

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Norgren, L, Patel, MR, Hiatt, WR, Wojdyla, DM, Fowkes, FGR, Baumgartner, I, Mahaffey, KW, Berger, JS, Jones, WS, Katona, BG, Held, P, Blomster, JI, Rockhold, FW, Björck, M, and EUCLID Steering Committee and Investigators, . "Outcomes of Patients with Critical Limb Ischaemia in the EUCLID Trial." European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery 55, no. 1 (January 2018): 109-117.

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Jones, WS, and Patel, MR. "Antithrombotic Therapy in Peripheral Artery Disease: Generating and Translating Evidence Into Practice." Journal of the American College of Cardiology 71, no. 3 (January 2018): 352-362. (Review)

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Kochar, A, Hellkamp, AS, Lokhnygina, Y, Jones, WS, Becker, RC, Berkowitz, SD, Breithardt, G, Fox, KAA, Halperin, JL, Hankey, GJ, Mahaffey, KW, Nessel, CC, Singer, DE, Piccini, JP, and Patel, MR. "Efficacy and safety of rivaroxaban compared with warfarin in patients with carotid artery disease and nonvalvular atrial fibrillation: Insights from the ROCKET AF trial." Clinical Cardiology 41, no. 1 (January 2018): 39-45.

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Doherty, JU, Kort, S, Mehran, R, Schoenhagen, P, and Soman, P. "ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for Multimodality Imaging in Valvular Heart Disease." Journal of Nuclear Cardiology 24, no. 6 (December 2017): 2043-2063.

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