Matthew Sinclair, MD

Medical Instructor in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 300 W. Morgan Street, Durham, NC 27701
Phone (919) 668-0113
Email address

Where is your hometown?

North Massapequa, New York

Where did you train?

  • Undergraduate- Stony Brook University, Stony Brook, NY
  • Medical School- Howard University, Washington, DC
  • Residency- Hofstra Northwell School of Medicine, Manhasset, NY
  • Chief Resident- Hofstra Northwell School of Medicine, Manhasset, NY

Honors and Awards

  • Travel Award to Attend KIDNEYcon 2018 in Little Rock, Arkansas (April 2018)
  • ASN Kidney STARS Program Selection to Attend ASN Kidney Week 2014 in Philadelphia, PA (November 2014)
  • Howard University College of Medicine Academic Achievement Scholarship (2010-2013)
  • Stony Brook University Academic Achievement Scholarship (2007-2010)
  • 3rd place, National NKF Young Investigators Forum, 2020- Clinical Sciences

What are your career goals?

I hope to pursue a career as an academic nephrologist, where I will have the opportunity to educate trainees, work as a clinician, and progress as a researcher.  My current interests include cardiorenal, onconephrology, glomerular disease, and the use of point-of-care ultrasound for volume assessment. My current research involves looking at the outcomes of TAVR vs medical management in patients with advanced CKD.

What were you looking for in a fellowship program?

Collegial work environment, broad clinical exposure, great faculty mentorship, an institutional research training grant, and the ability to pursue an advanced degree.

What are the strengths of the Duke program?

The ability to get amazing, individualized training from a wide array of accomplished clinician educators and researchers who are truly invested in cultivating fellows into future leaders in the field.

What has surprised you most about Duke?

Everyone has been so nice and welcoming, and I find it incredibly easy to have meaningful conversations with people that I have just met.  This aspect of the program stood out to me on my interview day and has continued to impress me. 

What have you liked about living in Durham/RTP?

The cost of living is so reasonable (mind-blowing actually for this New Yorker) and on a fellow’s salary I can enjoy owning a beautiful home with my wife right in the heart of Durham.  The food scene is incredible and on off days I have the ability to take a 2-hour care ride and go to the beach, hike in the mountains, or just hang out near home and enjoy all the fun things that Durham/Chapel Hill/RTP have to offer. 

What advice would you give about moving to Durham?

Give it a chance and you won’t regret it.

What are your hobbies?

Hanging out with my wife and son, traveling, watching and attending sporting events and concerts

What are your career goals?

Faculty position at an academic institution as a clinician investigator with focus on healthcare disparities and outcomes among underserved patients with CKD and/or ESKD


Follow Matt on Twitter @mattysincs

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Education and Training

  • Fellowship, Nephrology, Duke University, 2018 - 2021
  • M.D., Howard University, College of Medicine, 2014


Sinclair, Matthew R., Maria Souli, Felicia Ruffin, Lawrence P. Park, Michael Dagher, Emily M. Eichenberger, Stacey A. Maskarinec, et al. “Staphylococcus aureus Bacteremia Among Patients Receiving Maintenance Hemodialysis: Trends in Clinical Characteristics and Outcomes.” Am J Kidney Dis 79, no. 3 (March 2022): 393-403.e1.

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Eichenberger, Emily M., Felicia Ruffin, Batu Sharma-Kuinkel, Michael Dagher, Lawrence Park, Celia Kohler, Matthew R. Sinclair, Stacey A. Maskarinec, and Vance G. Fowler. “Bacterial genotype and clinical outcomes in solid organ transplant recipients with Staphylococcus aureus bacteremia.” Transpl Infect Dis 23, no. 6 (December 2021): e13730.

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Eichenberger, Emily M., Michael Dagher, Matthew R. Sinclair, Stacey A. Maskarinec, Vance G. Fowler, and Jerome J. Federspiel. “Infective endocarditis and solid organ transplantation: Only worse outcomes during initial transplantation hospitalization.” Am Heart J 240 (October 2021): 63–72.

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Eichenberger, Emily M., Felicia Ruffin, Michael Dagher, Reginald Lerebours, Sin-Ho Jung, Batu Sharma-Kuinkel, Andrew N. Macintyre, et al. “Bacteremia in solid organ transplant recipients as compared to immunocompetent patients: Acute phase cytokines and outcomes in a prospective, matched cohort study.” Am J Transplant 21, no. 6 (June 2021): 2113–22.

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Sinclair, Matthew, and Christina M. Wyatt. “Regional and Racial Disparities in HIV-Related Kidney Disease.” Contrib Nephrol 199 (2021): 106–13.

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Hung, Anna, Matthew Sinclair, Marion Hemmersbach-Miller, Daniel Edmonston, and Christina Wyatt. “Prescribing rates and characteristics of recipients of tenofovir-containing regimens before and after market entry of tenofovir alafenamide.” J Manag Care Spec Pharm 26, no. 12 (December 2020): 1582–88.

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Živná, Martina, Kendrah Kidd, Mohamad Zaidan, Petr Vyleťal, Veronika Barešová, Kateřina Hodaňová, Jana Sovová, et al. “An international cohort study of autosomal dominant tubulointerstitial kidney disease due to REN mutations identifies distinct clinical subtypes.” Kidney Int 98, no. 6 (December 2020): 1589–1604.

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