Michael August Blazing, MD

Associate Professor of Medicine
Campus mail 7412HOSP North, Durham, NC 27710
Phone (919) 681-3945
Email address blazi001@mc.duke.edu

General focus: My research interests are in primary and secondary prevention of cardiovascular disease. Specifically, I am looking at compliance issues within the cardiology division and in the University as a whole with regard to evidence based treatment and secondary prevention of cardiovascular disease. I am using both retrospective and prospective collection of discharge data to try and analyze these trends. In the future, we hope to begin clinical trials with regard to various issues which are outstanding in primary and secondary prevention. Some of the issues include treatment of hypercholesterolemia in elderly patients, differences between the various statins with regard to affects on lipid profiles, and early treatment of hypercholesterolemia after MI.

As part of my work, I have served as a consultant with various drug companies with regard to focusing on active issues and treatment of hypercholesterolemia.

Key words: Primary prevention, secondary prevention, hyperlipidemia, homocysteine, and hypertension.

In Their Words

Education and Training

  • M.D., University of California, San Francisco, School of Medicine, 1987

Publications

Mielniczuk, Lisa M., Marc A. Pfeffer, Eldrin F. Lewis, Michael A. Blazing, James A. de Lemos, Satishkumar Mohanavelu, Jean Rouleau, Keith Fox, Terje R. Pedersen, and Robert M. Califf. “Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome..” Clin J Am Soc Nephrol 4, no. 11 (November 2009): 1811–17. https://doi.org/10.2215/CJN.03510509.

PMID
19820133
Full Text

Shelby, Rebecca A., Tamara J. Somers, Francis J. Keefe, Susan G. Silva, Daphne C. McKee, Lilin She, Sandra J. Waters, et al. “Pain catastrophizing in patients with noncardiac chest pain: relationships with pain, anxiety, and disability..” Psychosom Med 71, no. 8 (October 2009): 861–68. https://doi.org/10.1097/PSY.0b013e3181b49584.

PMID
19737857
Full Text

Califf, Robert M., Robert A. Harrington, and Michael A. Blazing. “Premature release of data from clinical trials of ezetimibe..” N Engl J Med 361, no. 7 (August 13, 2009): 712–17. https://doi.org/10.1056/NEJMsr0900910.

PMID
19675335
Full Text

Alexander, Karen P., Michael A. Blazing, Robert S. Rosenson, Elisabeth Hazard, Wilbert S. Aronow, Sidney C. Smith, and E Magnus Ohman. “Management of hyperlipidemia in older adults..” J Cardiovasc Pharmacol Ther 14, no. 1 (March 2009): 49–58. https://doi.org/10.1177/1074248408328927.

PMID
19124599
Full Text

Cannon, Christopher P., Robert P. Giugliano, Michael A. Blazing, Robert A. Harrington, John L. Peterson, Christine McCrary Sisk, John Strony, et al. “Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes..” Am Heart J 156, no. 5 (November 2008): 826–32. https://doi.org/10.1016/j.ahj.2008.07.023.

PMID
19061694
Full Text

Brilakis, Emmanouil S., James A. de Lemos, Christopher P. Cannon, Stephen D. Wiviott, Sabina A. Murphy, David A. Morrow, Marc S. Sabatine, et al. “Outcomes of patients with acute coronary syndrome and previous coronary artery bypass grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials)..” Am J Cardiol 102, no. 5 (September 1, 2008): 552–58. https://doi.org/10.1016/j.amjcard.2008.04.024.

PMID
18721511
Full Text

Mielniczuk, Lisa M., Marc A. Pfeffer, Eldrin F. Lewis, Michael A. Blazing, James A. de Lemos, Amy Shui, Satish Mohanavelu, Robert M. Califf, and Eugene Braunwald. “Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome..” Am Heart J 155, no. 4 (April 2008): 725–31. https://doi.org/10.1016/j.ahj.2007.11.031.

PMID
18371483
Full Text

McLean, Dalton S., Shmuel Ravid, Michael Blazing, Bernard Gersh, Amy Shui, and Christopher P. Cannon. “Effect of statin dose on incidence of atrial fibrillation: data from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) and Aggrastat to Zocor (A to Z) trials..” Am Heart J 155, no. 2 (February 2008): 298–302. https://doi.org/10.1016/j.ahj.2007.10.024.

PMID
18215600
Full Text

Lemos, James A. de, David A. Morrow, Michael A. Blazing, Petr Jarolim, Stephen D. Wiviott, Marc S. Sabatine, Robert M. Califf, and Eugene Braunwald. “Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: results from the A to Z trial..” J Am Coll Cardiol 50, no. 22 (November 27, 2007): 2117–24. https://doi.org/10.1016/j.jacc.2007.06.057.

PMID
18036447
Full Text

Prosnitz, Robert G., Jessica L. Hubbs, Elizabeth S. Evans, Su-Min Zhou, Xiaoli Yu, Michael A. Blazing, Donna R. Hollis, et al. “Prospective assessment of radiotherapy-associated cardiac toxicity in breast cancer patients: analysis of data 3 to 6 years after treatment..” Cancer 110, no. 8 (October 15, 2007): 1840–50. https://doi.org/10.1002/cncr.22965.

PMID
17763369
Full Text

Pages