Mihai Luchian Azoitei, PhD

Publications

Li, Dapeng, Simon Brackenridge, Lucy C. Walters, Olivia Swanson, Karl Harlos, Daniel Rozbesky, Derek W. Cain, et al. “Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.” Commun Biol 5, no. 1 (March 28, 2022): 271. https://doi.org/10.1038/s42003-022-03183-5.

PMID
35347236
Full Text

Swanson, Olivia, Brianna Rhodes, Avivah Wang, Shi-Mao Xia, Robert Parks, Haiyan Chen, Aja Sanzone, et al. “Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations.” Cell Rep 36, no. 7 (August 17, 2021): 109561. https://doi.org/10.1016/j.celrep.2021.109561.

PMID
34407396
Full Text

Saunders, Kevin O., Esther Lee, Robert Parks, David R. Martinez, Dapeng Li, Haiyan Chen, Robert J. Edwards, et al. “Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.” Nature 594, no. 7864 (June 2021): 553–59. https://doi.org/10.1038/s41586-021-03594-0.

PMID
33971664
Full Text

Marston, Daniel J., Marco Vilela, Jaewon Huh, Jinqi Ren, Mihai L. Azoitei, George Glekas, Gaudenz Danuser, John Sondek, and Klaus M. Hahn. “Multiplexed GTPase and GEF biosensor imaging enables network connectivity analysis.” Nat Chem Biol 16, no. 8 (August 2020): 826–33. https://doi.org/10.1038/s41589-020-0542-9.

PMID
32424303
Full Text

Azoitei, Mihai L., Jungsik Noh, Daniel J. Marston, Philippe Roudot, Christopher B. Marshall, Timothy A. Daugird, Sidney L. Lisanza, et al. “Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways.” J Cell Biol 218, no. 9 (September 2, 2019): 3077–97. https://doi.org/10.1083/jcb.201812073.

PMID
31420453
Full Text

O’Shaughnessy, Ellen C., Orrin J. Stone, Paul K. LaFosse, Mihai L. Azoitei, Denis Tsygankov, John M. Heddleston, Wesley R. Legant, et al. “Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor.” J Cell Biol 218, no. 9 (September 2, 2019): 3153–60. https://doi.org/10.1083/jcb.201903019.

PMID
31444239
Full Text

Azoitei, M. L., J. Noh, M. J. Sandi, P. Roudot, R. K. Rottapel, G. Danuser, and K. M. Hahn. “Novel biosensor reveals the regulation and coordination of GEF-H1 with protrusion machinery.” In Molecular Biology of the Cell, Vol. 28. AMER SOC CELL BIOLOGY, 2017.

Scholars@Duke

Azoitei, M. L., Y. A. Ban, O. Kalyuzhny, J. Guenaga, A. Schroeter, J. Porter, R. Wyatt, and William R. Schief. “Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5.” Proteins 82, no. 10 (October 2014): 2770–82. https://doi.org/10.1002/prot.24641.

PMID
25043744
Full Text

Azoitei, Mihai L., Yih-En Andrew Ban, Jean-Philippe Julien, Steve Bryson, Alexandria Schroeter, Oleksandr Kalyuzhniy, Justin R. Porter, et al. “Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.” J Mol Biol 415, no. 1 (January 6, 2012): 175–92. https://doi.org/10.1016/j.jmb.2011.10.003.

PMID
22061265
Full Text

Azoitei, Mihai L., Bruno E. Correia, Yih-En Andrew Ban, Chris Carrico, Oleksandr Kalyuzhniy, Lei Chen, Alexandria Schroeter, et al. “Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.” Science 334, no. 6054 (October 21, 2011): 373–76. https://doi.org/10.1126/science.1209368.

PMID
22021856
Full Text

Pages