Pamela Susan Douglas, MD

Professor of Medicine
Ursula Geller Distinguished Professor for Research in Cardiovascular Disease, in the School of Medicine
Member in the Duke Clinical Research Institute
Campus mail 200 Morris St Room 7710, Durham, NC 27701
Phone (919) 681-2690
Email address pamela.douglas@duke.edu

Pamela S Douglas MD is the Ursula Geller Professor of Research in Cardiovascular Diseases in the Department of Medicine at Duke University and Director of the Multimodality Imaging Program at Duke Clinical Research Institute. During her 30+ years of experience she has led several landmark multicenter government studies and pivotal industry clinical trials along with outcomes research studies.  She is renowned for her scientific and policy work in improving the quality and appropriateness of imaging in clinical care, clinical trials and registries and through development and dissemination of national standards for imaging utilization, informatics and analysis. She has been among the pioneers in a number of areas including heart disease in women, sports cardiology, and cardio-oncology. Dr. Douglas’ wealth of experience includes authorship of over 400 peer reviewed manuscripts and 30 practice guidelines, and service as the President of the American College of Cardiology, President of the American Society of Echocardiography, and Chief of Cardiology at both the University of Wisconsin and Duke University. She has also previously served on the faculties of the University of Pennsylvania and Harvard University. She currently serves on the External Advisory Council of the National Heart, Lung and Blood Institute and the Scientific Advisory Board of the Patient Advocate Foundation.

Education and Training

  • Fellow in Cardiology, Medicine, University of Pennsylvania, 1981 - 1984
  • Medical Resident, Medicine, University of Pennsylvania, 1978 - 1981
  • M.D., Virginia Commonwealth University, 1978

Publications

Sharma, Abhinav, James L. Januzzi, Sunil Suchindran, Adrian Coles, Udo Hoffmann, Maros Ferencik, Manesh R. Patel, Geoffrey S. Ginsburg, and Pamela S. Douglas. “Utility of High-Sensitivity Troponin Among Stable Patients With Chest Pain Undergoing Stress Imaging (from PROMISE). (Accepted)” The American Journal of Cardiology 158 (November 2021): 148–49. https://doi.org/10.1016/j.amjcard.2021.07.032.

PMID
34454709
Full Text

Curzen, Nick, Zoe Nicholas, Beth Stuart, Sam Wilding, Kayleigh Hill, James Shambrook, Zina Eminton, et al. “Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial.” Eur Heart J 42, no. 37 (October 1, 2021): 3844–52. https://doi.org/10.1093/eurheartj/ehab444.

PMID
34269376
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Takagi, Hidenobu, Jonathon A. Leipsic, Noah McNamara, Isabella Martin, Timothy A. Fairbairn, Takashi Akasaka, Bjarne L. Nørgaard, et al. “Trans-lesional fractional flow reserve gradient as derived from coronary CT improves patient management: ADVANCE registry.” Journal of Cardiovascular Computed Tomography, September 2, 2021. https://doi.org/10.1016/j.jcct.2021.08.003.

PMID
34518113
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Wang, Teresa, Pamela S. Douglas, and Nosheen Reza. “Gender Gaps in Salary and Representation in Academic Internal Medicine Specialties in the US.” Jama Intern Med 181, no. 9 (September 1, 2021): 1255–57. https://doi.org/10.1001/jamainternmed.2021.3469.

PMID
34251403
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Nanna, M. G., T. Y. Wang, K. Chiswell, J. L. Sun, S. Vemulapalli, U. Hoffmann, M. R. Patel, J. E. Udelson, C. B. Fordyce, and P. S. Douglas. “Estimating the real-world performance of the PROMISE minimal-risk tool.” Am Heart J 239 (September 2021): 100–109. https://doi.org/10.1016/j.ahj.2021.05.016.

PMID
34077743
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Vemulapalli, Sreekanth, Amanda Stebbins, W Schuyler Jones, J Antonio Gutierrez, Manesh R. Patel, Rowena J. Dolor, Patricia A. Pellikka, Brooke Alhanti, Udo Hoffmann, and Pamela S. Douglas. “Cardiovascular risk and outcomes in symptomatic patients with suspected coronary artery disease and non coronary vascular disease: A report from the PROMISE trial.” Am Heart J 242 (August 9, 2021): 82–91. https://doi.org/10.1016/j.ahj.2021.07.010.

PMID
34384742
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Foldyna, Borek, Roman Zeleznik, Parastou Eslami, Thomas Mayrhofer, Jan-Erik Scholtz, Maros Ferencik, Daniel O. Bittner, et al. “Small whole heart volume predicts cardiovascular events in patients with stable chest pain: insights from the PROMISE trial.” Eur Radiol 31, no. 8 (August 2021): 6200–6210. https://doi.org/10.1007/s00330-021-07695-2.

PMID
33501599
Full Text

Eliya, Yousif, Sera Whitelaw, Lehana Thabane, Adriaan A. Voors, Pamela S. Douglas, and Harriette G. C. Van Spall. “Temporal Trends and Clinical Trial Characteristics Associated With the Inclusion of Women in Heart Failure Trial Steering Committees: A Systematic Review.” Circ Heart Fail 14, no. 8 (August 2021): e008064. https://doi.org/10.1161/CIRCHEARTFAILURE.120.008064.

PMID
34281362
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Cremer, Paul C., Tom Kai Ming Wang, L Leonardo Rodriguez, Brian R. Lindman, Yiran Zhang, Alan Zajarias, Rebecca T. Hahn, et al. “Incidence and Clinical Significance of Worsening Tricuspid Regurgitation Following Surgical or Transcatheter Aortic Valve Replacement: Analysis From the PARTNER IIA Trial.” Circulation. Cardiovascular Interventions 14, no. 8 (August 2021): e010437. https://doi.org/10.1161/circinterventions.120.010437.

PMID
34266311
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Hahn, Rebecca T., Pamela S. Douglas, Wael A. Jaber, Jonathon Leipsic, Samir Kapadia, Vinod H. Thourani, Raj Makkar, et al. “Doppler Velocity Index Outcomes Following Surgical or Transcatheter Aortic Valve Replacement in the PARTNER Trials.” Jacc Cardiovasc Interv 14, no. 14 (July 26, 2021): 1594–1606. https://doi.org/10.1016/j.jcin.2021.04.007.

PMID
34217631
Full Text

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