Pamela Susan Douglas, MD

Professor of Medicine
Ursula Geller Professor for Research in Cardiovascular Disease, in the School of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7022 North Pavilion DUMC, Durham, NC 27715
Phone (919) 681-2690
Email address pamela.douglas@duke.edu

Pamela S Douglas MD is the Ursula Geller Professor of Research in Cardiovascular Diseases in the Department of Medicine at Duke University and Director of the Multimodality Imaging Program at Duke Clinical Research Institute. During her 30+ years of experience she has led several landmark multicenter government studies and pivotal industry clinical trials along with outcomes research studies.  She is renowned for her scientific and policy work in improving the quality and appropriateness of imaging in clinical care, clinical trials and registries and through development and dissemination of national standards for imaging utilization, informatics and analysis. She has been among the pioneers in a number of areas including heart disease in women, sports cardiology, and cardio-oncology. Dr. Douglas’ wealth of experience includes authorship of over 400 peer reviewed manuscripts and 30 practice guidelines, and service as the President of the American College of Cardiology, President of the American Society of Echocardiography, and Chief of Cardiology at both the University of Wisconsin and Duke University. She has also previously served on the faculties of the University of Pennsylvania and Harvard University. She currently serves on the External Advisory Council of the National Heart, Lung and Blood Institute and the Scientific Advisory Board of the Patient Advocate Foundation.

Education and Training

  • Fellow in Cardiology, Medicine, University of Pennsylvania, 1981 - 1984
  • Medical Resident, Medicine, University of Pennsylvania, 1978 - 1981
  • M.D., Virginia Commonwealth University, 1978

Publications

Lee, JM, Choi, G, Koo, B-K, Hwang, D, Park, J, Zhang, J, Kim, K-J, Tong, Y, Kim, HJ, Grady, L, Doh, J-H, Nam, C-W, Shin, E-S, Cho, Y-S, Choi, S-Y, Chun, EJ, Choi, J-H, Nørgaard, BL, Christiansen, E, Niemen, K, Otake, H, Penicka, M, de Bruyne, B, Kubo, T, Akasaka, T, Narula, J, Douglas, PS, Taylor, CA, and Kim, H-S. "Identification of High-Risk Plaques Destined to Cause Acute Coronary Syndrome Using Coronary Computed Tomographic Angiography and Computational Fluid Dynamics." JACC. Cardiovascular imaging (March 9, 2018).

PMID
29550316
Full Text

Januzzi, JL, Suchindran, S, Coles, A, Ferencik, M, Patel, MR, Hoffmann, U, Ginsburg, GS, Douglas, PS, and PROMISE Investigators, . "High-Sensitivity Troponin I and Coronary Computed Tomography in Symptomatic Outpatients With Suspected Coronary Artery Disease: Insights From the PROMISE Trial." JACC. Cardiovascular imaging (March 9, 2018).

PMID
29550314
Full Text

Genders, TSS, Coles, A, Hoffmann, U, Patel, MR, Mark, DB, Lee, KL, Steyerberg, EW, Hunink, MGM, Douglas, PS, and CAD Consortium and the PROMISE Investigators, . "The External Validity of Prediction Models for the Diagnosis of Obstructive Coronary Artery Disease in Patients With Stable Chest Pain: Insights From the PROMISE Trial." JACC. Cardiovascular imaging 11, no. 3 (March 2018): 437-446.

PMID
28624401
Full Text

Khouri, MG, Ky, B, Dunn, G, Plappert, T, Englefield, V, Rabineau, D, Yow, E, Barnhart, HX, St John Sutton, M, and Douglas, PS. "Echocardiography Core Laboratory Reproducibility of Cardiac Safety Assessments in Cardio-Oncology." Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 31, no. 3 (March 2018): 361-371.e3.

PMID
29395626
Full Text

Adamson, PD, Fordyce, CB, McAllister, DA, Udelson, JE, Douglas, PS, and Newby, DE. "Identification of patients with stable chest pain deriving minimal value from coronary computed tomography angiography: An external validation of the PROMISE minimal-risk tool." International journal of cardiology 252 (February 2018): 31-34.

PMID
29249436
Full Text

Ferencik, M, Mayrhofer, T, Bittner, DO, Emami, H, Puchner, SB, Lu, MT, Meyersohn, NM, Ivanov, AV, Adami, EC, Patel, MR, Mark, DB, Udelson, JE, Lee, KL, Douglas, PS, and Hoffmann, U. "Use of High-Risk Coronary Atherosclerotic Plaque Detection for Risk Stratification of Patients With Stable Chest Pain: A Secondary Analysis of the PROMISE Randomized Clinical Trial." JAMA cardiology 3, no. 2 (February 2018): 144-152.

PMID
29322167
Full Text

Clement, ME, Lin, L, Navar, AM, Okeke, NL, Naggie, S, and Douglas, PS. "Lower likelihood of cardiac procedures after acute coronary syndrome in patients with human immunodeficiency virus/acquired immunodeficiency syndrome." Medicine 97, no. 6 (February 2018): e9849-.

PMID
29419696
Full Text

Szerlip, M, Gualano, S, Holper, E, Squiers, JJ, White, JM, Doshi, D, Williams, MR, Hahn, RT, Webb, JG, Svensson, LG, Kirtane, AJ, Cohen, DJ, Douglas, PS, Alu, MC, Crowley, A, Tuzcu, EM, Makkar, RR, Herrmann, HC, Babaliaros, V, Thourani, VH, Leon, MB, Kodali, SK, and Mack, MJ. "Sex-Specific Outcomes of Transcatheter Aortic Valve Replacement With the SAPIEN 3 Valve: Insights From the PARTNER II S3 High-Risk and Intermediate-Risk Cohorts." JACC. Cardiovascular interventions 11, no. 1 (January 2018): 13-20.

PMID
29301644
Full Text

Vemulapalli, S, Holmes, DR, Dai, D, Matsouaka, R, Mack, MJ, Grover, FL, Makkar, RR, Thourani, VH, and Douglas, PS. "Valve hemodynamic deterioration and cardiovascular outcomes in TAVR: A report from the STS/ACC TVT Registry." American heart journal 195 (January 2018): 1-13.

PMID
29224637
Full Text

Engelgau, MM, Peprah, E, Sampson, UKA, Mishoe, H, Benjamin, IJ, Douglas, PS, Hochman, JS, Ridker, PM, Brandes, N, Checkley, W, El-Saharty, S, Ezzati, M, Hennis, A, Jiang, L, Krumholz, HM, Lamourelle, G, Makani, J, Narayan, KMV, Ohene-Frempong, K, Straus, SE, Stuckler, D, Chambers, DA, Belis, D, Bennett, GC, Boyington, JE, Creazzo, TL, de Jesus, JM, Krishnamurti, C, Lowden, MR, Punturieri, A, Shero, ST, Young, NS, Zou, S, and Mensah, GA. "Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research." Global heart 12, no. 4 (December 2017): 341-348.

PMID
27452772
Full Text

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