Patrick Hank Pun, MD

Associate Professor of Medicine
Member of the Duke Clinical Research Institute
Campus mail Duke Box 17969, Durham, NC 27705
Phone (919) 668-8529

My current research interest is in understanding the mechanisms of cardiovascular disease among patients with chronic kidney disease, with a particular focus on the epidemic of sudden cardiac death. The ultimate goal is to reduce the impact of sudden death through improved risk stratification and novel risk mitigation therapies. Current investigations are focused on identifying novel genetic and biomarker risk factors among CKD patients, understanding the interplay of hemodialysis-specific exposures in the development of arrhythmias, and examining the risks and benefits of implantable cardioverter defibrillators among CKD patients using clinical trial and registry data.

Education and Training

  • Fellow in Nephrology, Medicine, Duke University, 2004 - 2007
  • Medical Resident, Medicine, Duke University, 2001 - 2004
  • M.D., Vanderbilt University, 2001

Publications

Assimon, Magdalene M., Patrick H. Pun, Lily Chin-Hua Wang, Sana M. Al-Khatib, M Alan Brookhart, David J. Weber, Wolfgang C. Winkelmayer, and Jennifer E. Flythe. “Analysis of Respiratory Fluoroquinolones and the Risk of Sudden Cardiac Death Among Patients Receiving Hemodialysis.” Jama Cardiol 7, no. 1 (January 1, 2022): 75–83. https://doi.org/10.1001/jamacardio.2021.4234.

PMID
34668928
Full Text

Hein, Aaron M., Julia J. Scialla, Jie-Lena Sun, Stephen J. Greene, Linda K. Shaw, Karen Chiswell, Patrick H. Pun, and Robert J. Mentz. “Estimated Glomerular Filtration Rate Variability in Patients With Heart Failure and Chronic Kidney Disease.” Journal of Cardiac Failure 27, no. 11 (November 2021): 1175–84. https://doi.org/10.1016/j.cardfail.2021.04.016.

PMID
33971291
Full Text

Lunyera, Joseph, Robert M. Clare, Karen Chiswell, Julia J. Scialla, Patrick H. Pun, Kevin L. Thomas, Monique A. Starks, and Clarissa J. Diamantidis. “Racial Differences in AKI Incidence Following Percutaneous Coronary Intervention.” J Am Soc Nephrol 32, no. 3 (March 2021): 654–62. https://doi.org/10.1681/ASN.2020040502.

PMID
33443096
Full Text

Pun, Patrick H., Sean D. Pokorney, and Christopher B. Granger. “Warfarin for Atrial Fibrillation Stroke Prophylaxis in Advanced Kidney Disease: If You Are Not Confused, You Are Not Thinking Clearly.” Jacc Clin Electrophysiol 6, no. 13 (December 14, 2020): 1669–71. https://doi.org/10.1016/j.jacep.2020.07.020.

PMID
33334445
Full Text

Pun, Patrick H., Craig S. Parzynski, Daniel J. Friedman, Gillian Sanders, Jeptha P. Curtis, and Sana M. Al-Khatib. “Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis.” Clin J Am Soc Nephrol 15, no. 11 (November 6, 2020): 1622–30. https://doi.org/10.2215/CJN.07920520.

PMID
32967922
Full Text

Hofacker, Samuel A., Matthew E. Dupre, Kimberly Vellano, Bryan McNally, Monique Anderson Starks, Myles Wolf, Laura P. Svetkey, and Patrick H. Pun. “Association between patient race and staff resuscitation efforts after cardiac arrest in outpatient dialysis clinics: A study from the CARES surveillance group.” Resuscitation 156 (November 2020): 42–50. https://doi.org/10.1016/j.resuscitation.2020.07.036.

PMID
32860854
Full Text

Hofacker, Samuel A., Laura J. Fish, Audrey L. Blewer, and Patrick H. Pun. “Barriers and Facilitators to Performing Cardiopulmonary Resuscitation During Treatment in Outpatient Hemodialysis Clinics: A Qualitative Study.” Nephrol Nurs J 47, no. 5 (September 2020): 401–11.

PMID
33107712
Scholars@Duke

Assimon, Magdalene M., Lily Wang, Patrick H. Pun, Wolfgang C. Winkelmayer, and Jennifer E. Flythe. “Use of QT Prolonging Medications by Hemodialysis Patients and Individuals Without End-Stage Kidney Disease.” J Am Heart Assoc 9, no. 13 (July 7, 2020): e015969. https://doi.org/10.1161/JAHA.120.015969.

PMID
32578475
Full Text

Edmonston, Daniel L., and Patrick H. Pun. “Coronary artery disease in chronic kidney disease: highlights from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.” Kidney Int 97, no. 4 (April 2020): 642–44. https://doi.org/10.1016/j.kint.2019.12.010.

PMID
32093916
Full Text

Starks, Monique Anderson, Jingjing Wu, Eric D. Peterson, Judith A. Stafford, Roland A. Matsouaka, L Ebony Boulware, Laura P. Svetkey, Paul S. Chan, Patrick H. Pun, and Patrick H. for American Heart Association’s Get With the Guidelines-Resuscitation Investigators. “In-Hospital Cardiac Arrest Resuscitation Practices and Outcomes in Maintenance Dialysis Patients.” Clin J Am Soc Nephrol 15, no. 2 (February 7, 2020): 219–27. https://doi.org/10.2215/CJN.05070419.

PMID
31911423
Full Text

Pages