Hematologic Malignancies and Cellular Therapy

Phuong Linh Doan, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Affiliate of the Duke Regeneration Center
Campus mail 595 Lasalle St, Snyderman Building, Box 103866, Durham, NC 27710
Phone (919) 613-2625
Email address phuong.doan@duke.edu

Education and Training

  • Fellowship, Hematology, Oncology, Cellular Therapy, Duke University School of Medicine, 2007 - 2010
  • Chief Medical Resident, University of North Carolina, Chapel Hill, School of Medicine, 2006 - 2007
  • Resident, Internal Medicine, University of North Carolina, Chapel Hill, School of Medicine, 2003 - 2006
  • M.D., University of North Carolina - Chapel Hill, 2003

Grants

Publications

Kam, Angel Y. F., Sadhna O. Piryani, Chang-Lung Lee, David A. Rizzieri, Neil L. Spector, Stefanie Sarantopoulos, and Phuong L. Doan. “Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells.” Mol Cancer Res 19, no. 5 (May 2021): 886–99. https://doi.org/10.1158/1541-7786.MCR-20-0973.

PMID
33514658
Full Text

Piryani, Sadhna O., Angel Y. F. Kam, Uyen T. Vu, Nelson J. Chao, and Phuong L. Doan. “CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation.” Stem Cell Reports 13, no. 1 (July 9, 2019): 76–90. https://doi.org/10.1016/j.stemcr.2019.04.023.

PMID
31155503
Full Text

Kam, Angel Y. F., Sadhna O. Piryani, Chad M. McCall, Hee Su Park, David A. Rizzieri, and Phuong L. Doan. “Targeting High Mobility Group Box-1 (HMGB1) Promotes Cell Death in Myelodysplastic Syndrome.” Clin Cancer Res 25, no. 13 (July 1, 2019): 4155–67. https://doi.org/10.1158/1078-0432.CCR-18-3517.

PMID
30952643
Full Text

Piryani, Sadhna O., Yiqun Jiao, Angel Y. F. Kam, Yang Liu, Tuan Vo-Dinh, Benny J. Chen, Nelson J. Chao, and Phuong L. Doan. “Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.” Int J Radiat Oncol Biol Phys 104, no. 2 (June 1, 2019): 291–301. https://doi.org/10.1016/j.ijrobp.2019.02.008.

PMID
30763662
Full Text

Piryani, Sadhna O., Yiqun Jiao, Angel Y. F. Kam, Yang Liu, Tuan Vo-Dinh, Benny J. Chen, Nelson J. Chao, and Phuong L. Doan. “Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.” In Blood, 132:2581–2581. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-117058.

Full Text

Piryani, Sadhna O., Angel Y. F. Kam, Evelyna G. Kliassov, Benny J. Chen, Neil L. Spector, John P. Chute, David S. Hsu, Nelson J. Chao, and Phuong L. Doan. “Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.” Stem Cells 36, no. 2 (February 2018): 252–64. https://doi.org/10.1002/stem.2731.

PMID
29086459
Full Text

Sung, Anthony D., Carlos M. de Castro, Thomas W. LeBlanc, Gwynn D. Long, Donna B. Adams, Danielle M. Brander, Sandeep Dave, et al. “Clinical Outcomes of Microtransplantation for Older Adults with Acute Myeloid Leukemia.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.

Scholars@Duke

Sundaramoorthy, Pasupathi, Qinhong Wang, Zhihong Zheng, Yiqun Jiao, Benny J. Chen, Phuong L. Doan, Nelson J. Chao, and Yubin Kang. “Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.” Stem Cell Research & Therapy 8, no. 1 (November 15, 2017): 263. https://doi.org/10.1186/s13287-017-0711-2.

PMID
29141658
Full Text

Racioppi, Luigi, William Lento, Wei Huang, Stephanie Arvai, Phuong L. Doan, Jeffrey R. Harris, Fernando Marcon, Helder I. Nakaya, Yaping Liu, and Nelson Chao. “Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration.” Cell Death Dis 8, no. 10 (October 5, 2017): e3076. https://doi.org/10.1038/cddis.2017.474.

PMID
28981105
Full Text

Himburg, Heather A., Phuong L. Doan, Mamle Quarmyne, Xiao Yan, Joshua Sasine, Liman Zhao, Grace V. Hancock, et al. “Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms.” Nat Med 23, no. 1 (January 2017): 91–99. https://doi.org/10.1038/nm.4251.

PMID
27918563
Full Text

Pages