Rebekah Ryanne Wu, MD

Assistant Professor of Medicine
Member of Duke Center for Applied Genomics and Precision Medicine
Campus mail 104427, Durham, NC 27710
Phone (919) 286-0411
Email address ryanne.wu@duke.edu

Dr. Wu is an internal medicine physician and health services researcher. Her main research interest is the use of precision medicine applications to improve clinical care. She is involved in projects currently looking at a patient-facing family history risk assessment tool, MeTree, which provides individualized risk stratification and clinical decision support recommendations to clinicians and patients. In addition she is also involved in a large scale sequencing project in Singapore looking at the intersection of family health history and genomics to better understand how these data elements can complement one another and create more precise risk predictions.  Dr. Wu is also a program director at the Cooperative Studies Program Epidemiology Center at the Durham VA Medical Center where she leads a team coordinating the VA's research efforts in understanding Gulf War Illness.

Education and Training

  • Chief Resident, Internal Medicine, Georgetown University School of Medicine, 2009 - 2010
  • Resident, Internal Medicine, Georgetown University School of Medicine, 2006 - 2009
  • M.D., University of North Carolina at Chapel Hill School of Medicine, 2006

Publications

Bylstra, Y., S. Davila, W. K. Lim, R. Wu, J. X. Teo, S. Kam, T. Lysaght, et al. “Implementation of genomics in medical practice to deliver precision medicine for an Asian population.” Npj Genomic Medicine 4, no. 1 (December 1, 2019). https://doi.org/10.1038/s41525-019-0085-8.

Full Text

Goldstein, Karen M., Deborah A. Fisher, R Ryanne Wu, Lori A. Orlando, Cynthia J. Coffman, Janet M. Grubber, Tejinder Rakhra-Burris, et al. “An electronic family health history tool to identify and manage patients at increased risk for colorectal cancer: protocol for a randomized controlled trial..” Trials 20, no. 1 (October 7, 2019). https://doi.org/10.1186/s13063-019-3659-y.

PMID
31590688
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Weitzel, Kristin Wiisanen, Benjamin Q. Duong, Meghan J. Arwood, Aniwaa Owusu-Obeng, Noura S. Abul-Husn, Barbara A. Bernhardt, Brian Decker, et al. “A stepwise approach to implementing pharmacogenetic testing in the primary care setting..” Pharmacogenomics 20, no. 15 (October 2019): 1103–12. https://doi.org/10.2217/pgs-2019-0053.

PMID
31588877
Full Text

Ginsburg, Geoffrey S., R Ryanne Wu, and Lori A. Orlando. “Family health history: underused for actionable risk assessment..” Lancet 394, no. 10198 (August 17, 2019): 596–603. https://doi.org/10.1016/S0140-6736(19)31275-9.

PMID
31395442
Full Text

Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Diasuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network..” Genet Med 21, no. 7 (July 2019). https://doi.org/10.1038/s41436-018-0280-5.

PMID
30158693
Full Text

Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Diasuke Goto, James K. Hicks, Ann M. Holmes, et al. “Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network..” Genet Med 21, no. 3 (March 2019): 743–47. https://doi.org/10.1038/s41436-018-0080-y.

PMID
29997387
Full Text

Wu, R Ryanne, Rachel A. Myers, Adam H. Buchanan, David Dimmock, Kimberly G. Fulda, Irina V. Haller, Susanne B. Haga, et al. “Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform..” Appl Clin Inform 10, no. 2 (March 2019): 180–88. https://doi.org/10.1055/s-0039-1679926.

PMID
30866001
Full Text

Wu, R Ryanne, Rachel A. Myers, Nina Sperber, Corrine I. Voils, Joan Neuner, Catherine A. McCarty, Irina V. Haller, et al. “Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework..” Genet Med 21, no. 2 (February 2019): 331–38. https://doi.org/10.1038/s41436-018-0049-x.

PMID
29875427
Full Text

Orlando, Lori A., Nina R. Sperber, Corrine Voils, Marshall Nichols, Rachel A. Myers, R Ryanne Wu, Tejinder Rakhra-Burris, et al. “Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group..” Genet Med 20, no. 6 (June 2018): 655–63. https://doi.org/10.1038/gim.2017.144.

PMID
28914267
Full Text

Orlando, Lori A., R. R. Wu, Adam Buchanan, Rachel A. Myers, and Geoffrey S. Ginsburg. “THE INTERSECTION OF POPULATION HEALTH AND PRECISION MEDICINE: EMPLOYING TECHNOLOGY TO OPTIMIZE RISK ASSESSMENT IN PRIMARY CARE.” In Journal of General Internal Medicine, 33:S362–S362. SPRINGER, 2018.

Scholars@Duke

Pages