Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Brummett, Beverly H., Michael A. Babyak, Rong Jiang, Kim M. Huffman, William E. Kraus, Abanish Singh, Elizabeth R. Hauser, Ilene C. Siegler, and Redford B. Williams. “Systolic Blood Pressure and Socioeconomic Status in a large multi-study population..” Ssm Popul Health 9 (December 2019). https://doi.org/10.1016/j.ssmph.2019.100498.

PMID
31650001
Full Text

Abdulrahim, Jawan W., Lydia Coulter Kwee, Elizabeth Grass, Ilene C. Siegler, Redford Williams, Ravi Karra, William E. Kraus, Simon G. Gregory, and Svati H. Shah. “Epigenome-Wide Association Study for All-Cause Mortality in a Cardiovascular Cohort Identifies Differential Methylation in Castor Zinc Finger 1 (CASZ1)..” J Am Heart Assoc 8, no. 21 (November 5, 2019). https://doi.org/10.1161/JAHA.119.013228.

PMID
31642367
Full Text

Fanaroff, Alexander C., Kristi Prather, Amanda Brucker, Daniel Wojdyla, Linda Davidson-Ray, Daniel B. Mark, Redford B. Williams, et al. “Relationship Between Optimism and Outcomes in Patients With Chronic Angina Pectoris..” Am J Cardiol 123, no. 9 (May 1, 2019): 1399–1405. https://doi.org/10.1016/j.amjcard.2019.01.036.

PMID
30771861
Full Text

Reavis, Zackery W., Cynthia M. Kuhn, Redford B. Williams, Richard S. Surwit, William E. Kraus, Kim M. Huffman, James D. Lane, Paul Costa, Ilene C. Siegler, and Anastasia Georgiades. “EIGHT-MONTH STABILITY OF PLASMA EPINEPHRINE AND CORTISOL IN FASTED ADULTS AT BASELINE AND IN RESPONSE TO A GLUCOSE BOLUS.” In Psychosomatic Medicine, 81:A41–42. LIPPINCOTT WILLIAMS & WILKINS, 2019.

Scholars@Duke

Georgiades, Anastasia, Zackery W. Reavis, Redford B. Williams, Cynthia M. Kuhn, William E. Kraus, Kim M. Huffman, James D. Lane, Paul Costa, Ilene C. Siegler, and Richard S. Surwit. “EPINEPHRINE, CORTISOL AND NON-ESTERIFIED FATTY ACID LEVELS DURING AN INTRAVENOUS GLUCOSE TOLERANCE TEST ARE ASSOCIATED WITH THE ACUTE INSULIN RESPONSE (AIR), AN EARLY RISK MARKER FOR TYPE 2 DIABETES.” In Psychosomatic Medicine, 81:A42–A42. LIPPINCOTT WILLIAMS & WILKINS, 2019.

Scholars@Duke

Boyle, Stephen H., Beverly H. Brummett, Cynthia M. Kuhn, John C. Barefoot, Ilene C. Siegler, Redford B. Williams, and Anastasia Georgiades. “The Effects of Tryptophan Enhancement and Depletion on Plasma Catecholamine Levels in Healthy Individuals..” Psychosom Med 81, no. 1 (January 2019): 34–40. https://doi.org/10.1097/PSY.0000000000000637.

PMID
30188382
Full Text

Do, Elizabeth K., Brett C. Haberstick, Redford B. Williams, Jeffrey M. Lessem, Andrew Smolen, Ilene C. Siegler, and Bernard F. Fuemmeler. “The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI..” Int J Obes (Lond) 43, no. 1 (January 2019): 33–42. https://doi.org/10.1038/s41366-018-0236-5.

PMID
30349010
Full Text

Jiang, Rong, Lydia Kwee, Svati H. Shah, Abanish Singh, Michael A. Babyak, Beverly H. Brummett, Ilene C. Siegler, Redford B. Williams, and Elizabeth R. Hauser. “Understanding of DNA methylation in the biological basis of stress related cardiovascular disease.” In Genetic Epidemiology, 42:708–708. WILEY, 2018.

Scholars@Duke

Singh, Abanish, Michael A. Babyak, Beverly H. Brummett, William E. Kraus, Ilene C. Siegler, Elizabeth R. Hauser, and Redford B. Williams. “Harmonizing psychosocial stress and CVD-risk variables for developing robust estimates of GxE analyses.” In Genetic Epidemiology, 42:731–731. WILEY, 2018.

Scholars@Duke

Clemow, Lynn P., Thomas G. Pickering, Karina W. Davidson, Joseph E. Schwartz, Virginia P. Williams, Jonathan A. Shaffer, Redford B. Williams, and William Gerin. “Stress management in the workplace for employees with hypertension: a randomized controlled trial..” Transl Behav Med 8, no. 5 (September 8, 2018): 761–70. https://doi.org/10.1093/tbm/iby018.

PMID
30202927
Full Text

Pages