Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Jiang, Rong, Michael A. Babyak, Beverly H. Brummett, Ilene C. Siegler, Cynthia M. Kuhn, and Redford B. Williams. “Corrigendum to "Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress" [Psychoneuroendocrinology 79 (2017) (May) 13-19].” Psychoneuroendocrinology 121 (November 2020): 104861. https://doi.org/10.1016/j.psyneuen.2020.104861.

PMID
32933770
Full Text

Singh, Abanish, Michael A. Babyak, Mario Sims, Solomon K. Musani, Beverly H. Brummett, Rong Jiang, William E. Kraus, et al. “Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants.” Transl Psychiatry 10, no. 1 (October 20, 2020): 351. https://doi.org/10.1038/s41398-020-01028-5.

PMID
33077726
Full Text

Meyer, Thomas, Isabel Rothe, Julia Staab, Hans-Christian Deter, Stella V. Fangauf, Stefanie Hamacher, Martin Hellmich, et al. “Length Polymorphisms in the Angiotensin I-Converting Enzyme Gene and the Serotonin-Transporter-Linked Polymorphic Region Constitute a Risk Haplotype for Depression in Patients with Coronary Artery Disease.” Biochem Genet 58, no. 4 (August 2020): 631–48. https://doi.org/10.1007/s10528-020-09967-w.

PMID
32367400
Full Text

Jonassaint, Charles R., Ilene C. Siegler, John C. Barefoot, Christopher L. Edwards, Edward C. Suarez, and Redford B. Williams. “Correction to: Low Life Course Socioeconomic Status (SES) Is Associated with Negative NEO PI-R Personality Patterns.” Int J Behav Med, July 31, 2020. https://doi.org/10.1007/s12529-020-09923-3.

PMID
32737809
Full Text

Brummett, B. H., S. H. Boyle, C. M. Kuhn, I. C. Siegler, E. C. Suarez, and R. B. Williams. “Corrigendum to "Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c" [J. Psychiatr Res. (2010) 44:373-377].” J Psychiatr Res 126 (July 2020): 142. https://doi.org/10.1016/j.jpsychires.2019.11.003.

PMID
31785784
Full Text

Jiang, Rong, Kim M. Huffman, Elizabeth R. Hauser, Janet L. Huebner, Monica J. Hubal, Redford B. Williams, Ilene C. Siegler, and William E. Kraus. “The role of brain-derived neurotropic factor (BDNF) genetic variants in exercise training.” In Genetic Epidemiology, 44:491–92, 2020.

Scholars@Duke

Williams, Redford B., and Virginia Williams. “THE WILLIAMS LIFESKILLS PROGRAM - A MEANS OF DELIVERING COGNITIVE BEHAVIORAL STRESS MANAGEMENT AND INTERPERSONAL SKILLS TRAINING IN DIVERSE CULTURES AROUND THE WORLD.” In Annals of Behavioral Medicine, 54:S206–S206, 2020.

Scholars@Duke

Fisher, Edwin B., Kate Lorig, Redford B. Williams, Joost Dekker, and Patrick Y. Tang. “DEFINING THE "IT" IN DISSEMINATION - CONCEPTUALIZATIONS AND STRATEGIES FOR GLOBAL EFFORTS.” In Annals of Behavioral Medicine, 54:S205–S205, 2020.

Scholars@Duke

Surwit, Richard S., Redford B. Williams, Ilene C. Siegler, James D. Lane, Michael Helms, Katherine L. Applegate, Nancy Zucker, Mark N. Feinglos, Cynthia M. McCaskill, and John C. Barefoot. “Erratum. Hostility, race, and glucose metabolism in nondiabetic individuals. Diabetes Care 2002;25:835-839.” Diabetes Care 43, no. 3 (March 2020): 691. https://doi.org/10.2337/dc20-er03.

PMID
31806650
Full Text

Brummett, Beverly H., Michael A. Babyak, Rong Jiang, Kim M. Huffman, William E. Kraus, Abanish Singh, Elizabeth R. Hauser, Ilene C. Siegler, and Redford B. Williams. “Systolic Blood Pressure and Socioeconomic Status in a large multi-study population.” Ssm Popul Health 9 (December 2019): 100498. https://doi.org/10.1016/j.ssmph.2019.100498.

PMID
31650001
Full Text

Pages