Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Jiang, Rong, Beverly H. Brummett, Michael A. Babyak, Ilene C. Siegler, and Redford B. Williams. “Brain-derived neurotrophic factor (BDNF) Val66Met and adulthood chronic stress interact to affect depressive symptoms..” J Psychiatr Res 47, no. 2 (February 2013): 233–39. https://doi.org/10.1016/j.jpsychires.2012.10.009.

PMID
23140671
Full Text

Brummett, Beverly H., Shirley B. Austin, Kathleen A. Welsh-Bohmer, Redford B. Williams, and Ilene C. Siegler. “Long-Term Impact of Caregiving and Metabolic Syndrome with Perceived Decline in Cognitive Function 8 Years Later: A Pilot Study Suggesting Important Avenues for Future Research..” Open J Med Psychol 2, no. 1 (January 2013): 23–28. https://doi.org/10.4236/ojmp.2013.21005.

PMID
24634805
Full Text

Berger, Jeffrey S., Richard C. Becker, Cynthia Kuhn, Michael J. Helms, Thomas L. Ortel, and Redford Williams. “Hyperreactive platelet phenotypes: relationship to altered serotonin transporter number, transport kinetics and intrinsic response to adrenergic co-stimulation..” Thromb Haemost 109, no. 1 (January 2013): 85–92. https://doi.org/10.1160/TH12-03-0202.

PMID
23223800
Full Text

Brummett, Beverly H., Michael A. Babyak, Rong Jiang, Svati H. Shah, Richard C. Becker, Carol Haynes, Megan Chryst-Ladd, et al. “A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events..” Plos One 8, no. 12 (2013). https://doi.org/10.1371/journal.pone.0082781.

PMID
24386118
Full Text

Proeschold-Bell, R. J., R. Swift, H. E. Moore, G. Bennett, X. -. F. Li, R. Blouin, V. P. Williams, R. B. Williams Jr, and D. Toole. “Corrigendum to "Use of a randomized multiple baseline design: Rationale and design of the Spirited Life holistic health intervention study" [Contemp Clin Trials 35 (2013) 138-152] (DOI:10.1016/j.cct.2013.05.005).” Contemporary Clinical Trials, 2013.

Scholars@Duke

Barnes, Vernon A., Maribeth H. Johnson, Redford B. Williams, and Virginia P. Williams. “IMPACT OF WILLIAMS LIFESKILLS® TRAINING ON ANGER, ANXIETY AND AMBULATORY BLOOD PRESSURE IN ADOLESCENTS..” Transl Behav Med 2, no. 4 (December 1, 2012): 401–10. https://doi.org/10.1007/s13142-012-0162-3.

PMID
23482659
Full Text

Jonassaint, Charles R., Allison Ashley-Koch, Keith E. Whitfield, Rick H. Hoyle, Laura Smart Richman, Ilene C. Siegler, Charmaine D. Royal, and Redford Williams. “The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach..” Biol Psychol 91, no. 1 (September 2012): 111–19. https://doi.org/10.1016/j.biopsycho.2012.05.004.

PMID
22659377
Full Text

Fuemmeler, Bernard F., Chongming Yang, Phil Costanzo, Rick H. Hoyle, Ilene C. Siegler, Redford B. Williams, and Truls Ostbye. “Parenting styles and body mass index trajectories from adolescence to adulthood..” Health Psychol 31, no. 4 (July 2012): 441–49. https://doi.org/10.1037/a0027927.

PMID
22545979
Full Text

Brummett, Beverley H., Ilene C. Siegler, Redford B. Williams, and Peggye Dilworth-Anderson. “Associations of Social Support and 8-Year Follow-Up Depressive Symptoms: Differences in African American and White Caregivers..” Clin Gerontol 35, no. 4 (June 1, 2012): 289–302. https://doi.org/10.1080/07317115.2012.678569.

PMID
23144529
Full Text

Babyak, Michael A., Sarah Schwartz, Rong Jiang, Beverly Brummett, John S. Kauwe, Chris Corcoran, Ronald Munger, Kathleen Welsh-Bohmer, Redford B. Williams, and Maria Norton. “PSYCHOSOCIAL STRESS IN MIDLIFE MAY MODERATE EFFECTS OF APOE-TOMM40 RS157580 ON METABOLIC TRAITS IN LATE LIFE.” Annals of Behavioral Medicine 43 (April 1, 2012): S180–S180.

Scholars@Duke

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