Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address robert.mentz@duke.edu

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I serve our group as Chief of the Heart Failure Section. I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Cardiometabolic disease
  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003

Publications

Jawitz, Oliver K., Vignesh Raman, Yaron D. Barac, Jatin Anand, Chetan B. Patel, Robert J. Mentz, Adam D. DeVore, and Carmelo Milano. “Influence of donor brain death duration on outcomes following heart transplantation: A United Network for Organ Sharing Registry analysis.” J Thorac Cardiovasc Surg 159, no. 4 (April 2020): 1345-1353.e2. https://doi.org/10.1016/j.jtcvs.2019.04.060.

PMID
31147170
Full Text

Bhatt, Ankeet S., Andrew P. Ambrosy, Allison Dunning, Adam D. DeVore, Javed Butler, Shelby Reed, Adriaan Voors, et al. “The burden of non-cardiac comorbidities and association with clinical outcomes in an acute heart failure trial - insights from ASCEND-HF.” European Journal of Heart Failure, March 25, 2020. https://doi.org/10.1002/ejhf.1795.

PMID
32212297
Full Text

Standl, Eberhard, Susanna R. Stevens, Yuliya Lokhnygina, M Angelyn Bethel, John B. Buse, Stephanie M. Gustavson, Aldo P. Maggioni, et al. “Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL.” Diabetes Care 43, no. 3 (March 2020): 643–52. https://doi.org/10.2337/dc19-1079.

PMID
31882409
Full Text

Mentz, Robert J., Adam D. DeVore, Gudaye Tasissa, John F. Heitner, Ileana L. Piña, Anuradha Lala, Robert T. Cole, et al. “PredischaRge initiation of Ivabradine in the ManagEment of Heart Failure: Results of the PRIME-HF Trial.” Am Heart J 223 (February 28, 2020): 98–105. https://doi.org/10.1016/j.ahj.2019.12.024.

PMID
32217365
Full Text

Grubb, Alex, and Robert J. Mentz. “Pharmacological management of atrial fibrillation in patients with heart failure with reduced ejection fraction: review of current knowledge and future directions.” Expert Review of Cardiovascular Therapy 18, no. 2 (February 25, 2020): 85–101. https://doi.org/10.1080/14779072.2020.1732210.

PMID
32066285
Full Text

Cooper, Lauren B., Lina Benson, Robert J. Mentz, Gianluigi Savarese, Adam D. DeVore, Juan-Jesus Carrero, Ulf Dahlström, et al. “Association between potassium level and outcomes in heart failure with reduced ejection fraction: a cohort study from the Swedish Heart Failure Registry.” In Eur J Heart Fail, 2020. https://doi.org/10.1002/ejhf.1757.

PMID
32078214
Full Text

Bethel, M Angelyn, Robert J. Mentz, Peter Merrill, John B. Buse, Juliana C. Chan, Shaun G. Goodman, Nayyar Iqbal, et al. “Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial.” Diabetes Care 43, no. 2 (February 2020): 446–52. https://doi.org/10.2337/dc19-1065.

PMID
31757838
Full Text

Reed, Shelby D., Yanhong Li, Helen A. Dakin, Frauke Becker, Jose Leal, Stephanie M. Gustavson, Bernt Kartman, et al. “Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).” Diabetes Care 43, no. 2 (February 2020): 374–81. https://doi.org/10.2337/dc19-0950.

PMID
31806653
Full Text

Masson, Rajeev, Andrew P. Ambrosy, Kevin Kheder, Marat Fudim, Robert M. Clare, Adrian Coles, Adrian F. Hernandez, et al. “A Novel In-hospital Congestion Score to Risk Stratify Patients Admitted for Worsening Heart Failure (from ASCEND-HF).” J Cardiovasc Transl Res, January 13, 2020. https://doi.org/10.1007/s12265-020-09954-x.

PMID
31933144
Full Text

Jawitz, Oliver K., Marat Fudim, Vignesh Raman, Vanessa Blumer, Kadir Caliskan, Adam D. DeVore, Robert J. Mentz, et al. “Renal Outcomes in Patients Bridged to Heart Transplant With a Left Ventricular Assist Device.” Ann Thorac Surg, January 3, 2020. https://doi.org/10.1016/j.athoracsur.2019.11.021.

PMID
31904371
Full Text

Pages