Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I serve our group as Chief of the Heart Failure Section. I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Cardiometabolic disease
  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003


Pandey, Ambarish, Kershaw V. Patel, Wanpen Vongpatanasin, Colby Ayers, Jarett D. Berry, Robert J. Mentz, Michael J. Blaha, et al. “Incorporation of Biomarkers Into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 ACC/AHA High Blood Pressure Guideline: A Pooled Cohort Analysis.” Circulation 140, no. 25 (December 17, 2019): 2076–88.

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Fudim, Marat, Andrew R. Spector, Maria-Rosa Costanzo, Sean D. Pokorney, Robert J. Mentz, Dariusz Jagielski, Ralph Augostini, et al. “Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea: A Pooled Cohort Analysis.” J Clin Sleep Med 15, no. 12 (December 15, 2019): 1747–55.

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Logan, Juliette K., and Robert J. Mentz. “Targeting Natriuretic Peptide Levels in Heart Failure with Therapy: Does "X" Really Mark the Spot?” Curr Heart Fail Rep 16, no. 6 (December 2019): 250–56.

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Reed, Shelby D., Angelyn O. Fairchild, F Reed Johnson, Juan Marcos Gonzalez, Robert J. Mentz, Mitchell W. Krucoff, and Sreekanth Vemulapalli. “Patients' Willingness to Accept Mitral Valve Procedure-Associated Risks Varies Across Severity of Heart Failure Symptoms.” Circ Cardiovasc Interv 12, no. 12 (December 2019): e008051.

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Badjatiya, Anish, Peter Merrill, John B. Buse, Shaun G. Goodman, Brian Katona, Nayyar Iqbal, Neha J. Pagidipati, et al. “Clinical Outcomes in Patients With Type 2 Diabetes Mellitus and Peripheral Artery Disease: Results From the EXSCEL Trial.” Circ Cardiovasc Interv 12, no. 12 (December 2019): e008018.

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Bhatt, Ankeet S., Nancy Luo, Nicole Solomon, Neha J. Pagidipati, Giuseppe Ambrosio, Jennifer B. Green, Darren K. McGuire, et al. “International variation in characteristics and clinical outcomes of patients with type 2 diabetes and heart failure: Insights from TECOS.” Am Heart J 218 (December 2019): 57–65.

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Regan, Jessica A., Dalane W. Kitzman, Eric S. Leifer, William E. Kraus, Jerome L. Fleg, Daniel E. Forman, David J. Whellan, et al. “Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction.” Jacc Heart Fail 7, no. 12 (December 2019): 1056–65.

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Pandey, Ambarish, Dalane Kitzman, David J. Whellan, Pamela W. Duncan, Robert J. Mentz, Amy M. Pastva, M Benjamin Nelson, Bharathi Upadhya, Haiying Chen, and Gordon R. Reeves. “Frailty Among Older Decompensated Heart Failure Patients: Prevalence, Association With Patient-Centered Outcomes, and Efficient Detection Methods.” Jacc Heart Fail 7, no. 12 (December 2019): 1079–88.

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Feng, Kent Y., Christopher M. Oconnor, Robert Clare, Brooke Alhanti, Ileana L. Pina, William E. Kraus, David J. Whellan, and Robert J. Mentz. “Exploring the Implications of Pain Symptoms in Patients With Heart Failure.” In Circulation, Vol. 140, 2019.


Samsky, Marc D., Li Lin, Stephen J. Greene, Steven J. Lippmann, Pamela N. Peterson, Paul A. Heidenreich, Warren K. Laskey, et al. “Patient Perceptions and Familiarity With Medical Therapy for Heart Failure.” Jama Cardiol, November 17, 2019.

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