Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address robert.mentz@duke.edu

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003

Publications

Inohara, Taku, Pratik Manandhar, Andrzej S. Kosinski, Roland A. Matsouaka, Shun Kohsaka, Robert J. Mentz, Vinod H. Thourani, et al. “Association of Renin-Angiotensin Inhibitor Treatment With Mortality and Heart Failure Readmission in Patients With Transcatheter Aortic Valve Replacement..” Jama 320, no. 21 (December 4, 2018): 2231–41. https://doi.org/10.1001/jama.2018.18077.

PMID
30512100
Full Text

Sharma, Abhinav, Andrew P. Ambrosy, Adam D. DeVore, Kenneth B. Margulies, Steven E. McNulty, Robert J. Mentz, Adrian F. Hernandez, et al. “Liraglutide and weight loss among patients with advanced heart failure and a reduced ejection fraction: insights from the FIGHT trial..” In Esc Heart Fail, 5:1035–43, 2018. https://doi.org/10.1002/ehf2.12334.

PMID
30120812
Full Text

Mediano, Mauro F. F., Eric S. Leifer, Lawton S. Cooper, Steven J. Keteyian, William E. Kraus, Robert J. Mentz, and Jerome L. Fleg. “Influence of Baseline Physical Activity Level on Exercise Training Response and Clinical Outcomes in Heart Failure: The HF-ACTION Trial..” Jacc Heart Fail 6, no. 12 (December 2018): 1011–19. https://doi.org/10.1016/j.jchf.2018.09.012.

PMID
30497641
Full Text

Mentz, Robert J., Vivian P. Thompson, David Aguilar, Jasmine Choi, Stephanie M. Gustavson, Nayyar Iqbal, Alice P. Kong, et al. “Effects of Once-Weekly Exenatide on Clinical Outcomes in Patients With Preexisting Cardiovascular Disease..” Circulation 138, no. 22 (November 27, 2018): 2576–78. https://doi.org/10.1161/CIRCULATIONAHA.118.036811.

PMID
30571356
Full Text

Warraich, Haider J., Dalane W. Kitzman, David J. Whellan, Pamela W. Duncan, Robert J. Mentz, Amy M. Pastva, M Benjamin Nelson, Bharathi Upadhya, and Gordon R. Reeves. “Physical Function, Frailty, Cognition, Depression, and Quality of Life in Hospitalized Adults ≥60 Years With Acute Decompensated Heart Failure With Preserved Versus Reduced Ejection Fraction..” In Circ Heart Fail, Vol. 11, 2018. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005254.

PMID
30571197
Full Text

Pandey, Ambarish, Nitin Kondamudi, Kershaw V. Patel, Colby Ayers, Shawn Simek, Michael E. Hall, Solomon K. Musani, et al. “Association Between Regional Adipose Tissue Distribution and Risk of Heart Failure Among Blacks..” Circ Heart Fail 11, no. 11 (November 2018). https://doi.org/10.1161/CIRCHEARTFAILURE.118.005629.

PMID
30571193
Full Text

Fudim, Marat, Kishan S. Parikh, Allison Dunning, Adam D. DeVore, Robert J. Mentz, Phillip J. Schulte, Paul W. Armstrong, et al. “Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF)..” Am J Cardiol 122, no. 9 (November 1, 2018): 1506–12. https://doi.org/10.1016/j.amjcard.2018.07.023.

PMID
30172362
Full Text

Fudim, Marat, Christopher M. O’Connor, Hillary Mulder, Adrian Coles, Ankeet S. Bhatt, Andrew P. Ambrosy, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Loop diuretic adjustments in patients with chronic heart failure: Insights from HF-ACTION..” Am Heart J 205 (November 2018): 133–41. https://doi.org/10.1016/j.ahj.2018.06.017.

PMID
30158057
Full Text

Warraich, Haider Javed, Joseph G. Rogers, Shannon M. Dunlay, Ellen Hummel, and Robert J. Mentz. “Top Ten Tips for Palliative Care Clinicians Caring for Heart Failure Patients..” J Palliat Med 21, no. 11 (November 2018): 1646–50. https://doi.org/10.1089/jpm.2018.0453.

PMID
30311835
Full Text

Mentz, Robert J., M Angelyn Bethel, Peter Merrill, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, João S. Felício, et al. “Effect of Once-Weekly Exenatide on Clinical Outcomes According to Baseline Risk in Patients With Type 2 Diabetes Mellitus: Insights From the EXSCEL Trial..” J Am Heart Assoc 7, no. 19 (October 2, 2018). https://doi.org/10.1161/JAHA.118.009304.

PMID
30371301
Full Text

Pages