Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003


Mentz, R. J., M. Fiuzat, K. Chiswell, D. Wojdyla, B. Davison, J. Cleland, H. C. Dittrich, et al. “The PROTECT In-Hospital Risk Model: 7-Day Outcome in Patients Hospitalized with Acute Heart Failure (AHF) and Renal Dysfunction.” In Journal of Cardiac Failure, 17:S77–S77. Elsevier BV, 2011.

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Patel, C., R. J. Mentz, J. Suarez, A. F. Hernandez, G. M. Felker, C. M. O’Connor, and J. G. Rogers. “Association between VE-VCO2 Slope and Resting Hemodynamic Measurements in Ambulatory Heart Failure (HF) Patients: An Analysis from the Duke Advanced HF Database.” Journal of Cardiac Failure 17, no. 8 (August 2011): S8–9.

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Mentz, R. J., M. Fiuzat, D. Wojdyla, K. Chiswell, K. Pieper, M. Gheorghiade, G. C. Fonarow, and C. M. O’Connor. “Clinical Characteristics and Outcomes for Hospitalized Heart Failure (HF) Patients with Chronic Obstructive Pulmonary Disease (COPD): Findings from OPTIMIZE-HF.” In Journal of Cardiac Failure, 17:S86–87. Elsevier BV, 2011.

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Kanwar, Manreet K., Lisa C. Lohmueller, Robert L. Kormos, Natasha A. Loghmanpour, Raymond L. Benza, Robert J. Mentz, Stephen H. Bailey, Srinivas Murali, and James F. Antaki. “Low Accuracy of the HeartMate Risk Score for Predicting Mortality Using the INTERMACS Registry Data..” Asaio J 63, no. 3 (n.d.): 251–56.

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Cooper, Lauren B., Bradley G. Hammill, Larry A. Allen, JoAnn Lindenfeld, Robert J. Mentz, Joseph G. Rogers, Carmelo A. Milano, Chetan B. Patel, Karen P. Alexander, and Adrian F. Hernandez. “Assessing Frailty in Patients Undergoing Destination Therapy Left Ventricular Assist Device: Observations from Interagency Registry for Mechanically Assisted Circulatory Support..” Asaio J 64, no. 1 (n.d.): 16–23.

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