Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003


Onwuemene, Oluwatoyosi A., Steven C. Grambow, Chetan B. Patel, Robert J. Mentz, Carmelo A. Milano, Joseph G. Rogers, Ara D. Metjian, Gowthami M. Arepally, and Thomas L. Ortel. “Indications for and outcomes of therapeutic plasma exchange after cardiac transplantation: A single center retrospective study..” J Clin Apher 33, no. 4 (August 2018): 469–79.

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Vaduganathan, Muthiah, Ravi B. Patel, Robert J. Mentz, Haris Subacius, Neal A. Chatterjee, Stephen J. Greene, Andrew P. Ambrosy, et al. “Sudden Death After Hospitalization for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial)..” Am J Cardiol 122, no. 2 (July 15, 2018): 255–60.

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Kelly, Jacob P., Melissa Greiner, Elsayed Z. Soliman, Tiffany C. Randolph, Kevin L. Thomas, Shannon M. Dunlay, Lesley H. Curtis, Emily C. O’Brien, and Robert J. Mentz. “Relation of Early Repolarization (J Point Elevation) to Mortality in Blacks (from the Jackson Heart Study)..” Am J Cardiol 122, no. 2 (July 15, 2018): 340–46.

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Mentz, Robert J., and Stephen J. Greene. “Adding Troponin to the Puzzle of Heart Failure With Preserved Ejection Fraction: Marker or Mediator?.” J Am Coll Cardiol 72, no. 1 (July 3, 2018): 41–44.

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Fudim, Marat, and Robert J. Mentz. “Early versus late readmission during the vulnerable phase following hospitalization for heart failure: reply..” Eur J Heart Fail 20, no. 7 (July 2018).

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Verma, Amanda K., Jie-Lena Sun, Adrian Hernandez, John R. Teerlink, Phillip J. Schulte, Justin Ezekowitz, Adriaan Voors, et al. “Rate pressure product and the components of heart rate and systolic blood pressure in hospitalized heart failure patients with preserved ejection fraction: Insights from ASCEND-HF..” Clin Cardiol 41, no. 7 (July 2018): 945–52.

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Warraich, Haider J., Christopher O’Connor, Angie Wu, Adrian Coles, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Differences Between Patients Enrolled Early and Late During Clinical Trial Recruitment: Insights From the HF-ACTION Trial..” Circ Cardiovasc Qual Outcomes 11, no. 7 (July 2018).

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Kamimura, Daisuke, Loretta R. Cain, Robert J. Mentz, Wendy B. White, Michael J. Blaha, Andrew P. DeFilippis, Ervin R. Fox, et al. “Cigarette Smoking and Incident Heart Failure: Insights From the Jackson Heart Study..” Circulation 137, no. 24 (June 12, 2018): 2572–82.

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Greene, Stephen J., Emily C. O’Brien, Robert J. Mentz, Nancy Luo, N Chantelle Hardy, Warren K. Laskey, Paul A. Heidenreich, et al. “Home-Time After Discharge Among Patients Hospitalized With Heart Failure..” J Am Coll Cardiol 71, no. 23 (June 12, 2018): 2643–52.

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