Rory Henderson, PhD

Publications

Edwards, Robert J., Katayoun Mansouri, Victoria Stalls, Kartik Manne, Brian Watts, Rob Parks, Katarzyna Janowska, et al. “Cold sensitivity of the SARS-CoV-2 spike ectodomain.” Nat Struct Mol Biol 28, no. 2 (February 2021): 128–31. https://doi.org/10.1038/s41594-020-00547-5.

PMID
33402708
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Gobeil, Sophie M-C, Katarzyna Janowska, Shana McDowell, Katayoun Mansouri, Robert Parks, Kartik Manne, Victoria Stalls, et al. “D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction.” Cell Rep 34, no. 2 (January 12, 2021): 108630. https://doi.org/10.1016/j.celrep.2020.108630.

PMID
33417835
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Henderson, Rory, Robert J. Edwards, Katayoun Mansouri, Katarzyna Janowska, Victoria Stalls, Sophie M. C. Gobeil, Megan Kopp, et al. “Controlling the SARS-CoV-2 spike glycoprotein conformation.” Nat Struct Mol Biol 27, no. 10 (October 2020): 925–33. https://doi.org/10.1038/s41594-020-0479-4.

PMID
32699321
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Henderson, Rory, Maolin Lu, Ye Zhou, Zekun Mu, Robert Parks, Qifeng Han, Allen L. Hsu, et al. “Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.” Nat Commun 11, no. 1 (January 24, 2020): 520. https://doi.org/10.1038/s41467-019-14196-w.

PMID
31980614
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Acharya, P., R. Edwards, R. Henderson, K. Manne, K. Mansouri, K. Janowska, S. McDowell, V. Stalls, M. Kopp, and B. Haynes. “How does HIV env structure informs vaccine design?” Microscopy and Microanalysis, January 1, 2020. https://doi.org/10.1017/S1431927620015135.

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Saunders, Kevin O., Kevin Wiehe, Ming Tian, Priyamvada Acharya, Todd Bradley, S Munir Alam, Eden P. Go, et al. “Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.” Science 366, no. 6470 (December 6, 2019). https://doi.org/10.1126/science.aay7199.

PMID
31806786
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LaBranche, Celia C., Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, et al. “Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.” Plos Pathog 15, no. 12 (December 2019): e1008200. https://doi.org/10.1371/journal.ppat.1008200.

PMID
31790514
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LaBranche, Celia C., Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, et al. “Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.” Plos Pathog 15, no. 9 (September 2019): e1008026. https://doi.org/10.1371/journal.ppat.1008026.

PMID
31527908
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Henderson, Rory, Brian E. Watts, Hieu N. Ergin, Kara Anasti, Robert Parks, Shi-Mao Xia, Ashley Trama, et al. “Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies.” Nat Commun 10, no. 1 (February 8, 2019): 654. https://doi.org/10.1038/s41467-019-08415-7.

PMID
30737386
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Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, Melissa Cooper, et al. “Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.” Immunity 49, no. 6 (December 18, 2018): 1162-1174.e8. https://doi.org/10.1016/j.immuni.2018.10.015.

PMID
30552024
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