Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Writing Committee Members, Y Joseph, Catherine M. Otto, Rick A. Nishimura, Robert O. Bonow, Blase A. Carabello, John P. Erwin, Federico Gentile, et al. “2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.” J Thorac Cardiovasc Surg, May 7, 2021. https://doi.org/10.1016/j.jtcvs.2021.04.002.

PMID
33972115
Full Text

Carnicelli, Anthony P., Sana M. Al-Khatib, Denis Xavier, Frederik Dalgaard, Peter D. Merrill, Daniel M. Wojdyla, Basil S. Lewis, et al. “Premature permanent discontinuation of apixaban or warfarin in patients with atrial fibrillation.” Heart 107, no. 9 (May 2021): 713–20. https://doi.org/10.1136/heartjnl-2020-317229.

PMID
32938772
Full Text

Ali-Ahmed, Fatima, Frederik Dalgaard, Nancy M. Allen Lapointe, Andrzej S. Kosinski, Vanessa Blumer, Daniel P. Morin, Gillian D. Sanders, and Sana M. Al-Khatib. “Right ventricular lead location and outcomes among patients with cardiac resynchronization therapy: A meta-analysis.” Prog Cardiovasc Dis, April 20, 2021. https://doi.org/10.1016/j.pcad.2021.04.002.

PMID
33864874
Full Text

Al-Khatib, Sana M., Hillary Mulder, Daniel Wojdyla, Renato D. Lopes, Lars Wallentin, John H. Alexander, Ziad Hijazi, Shinya Goto, and Christopher B. Granger. “Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Left Ventricular Hypertrophy: Insights From the ARISTOTLE Trial.” Circ Arrhythm Electrophysiol 14, no. 3 (March 2021): e009614. https://doi.org/10.1161/CIRCEP.120.009614.

PMID
33657831
Full Text

Chery, Godefroy S., Nicholas Kamp, Andrzej S. Kosinski, Gillian Sanders Schmidler, Renato D. Lopes, Manesh Patel, and Sana M. Al-Khatib. “Response to: The paradox of implantable cardioverter-defibrillator: When guidelines play against care improvement.” Am Heart J 233 (March 2021): 151–52. https://doi.org/10.1016/j.ahj.2020.11.014.

PMID
33610195
Full Text

Al-Khatib, Sana M., Hillary Mulder, Daniel Wojdyla, Renato D. Lopes, Lars Wallentin, John H. Alexander, Ziad Hijazi, Shinya Goto, and Christopher B. Granger. “Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Left Ventricular Hypertrophy.” Circulation: Arrhythmia and Electrophysiology 14, no. 3 (March 2021). https://doi.org/10.1161/circep.120.009614.

Full Text

Otto, Catherine M., Rick A. Nishimura, Robert O. Bonow, Blase A. Carabello, John P. Erwin, Federico Gentile, Hani Jneid, et al. “2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.” Circulation 143, no. 5 (February 2, 2021): e35–71. https://doi.org/10.1161/CIR.0000000000000932.

PMID
33332149
Full Text

Otto, Catherine M., Rick A. Nishimura, Robert O. Bonow, Blase A. Carabello, Erwin John P. III, Federico Gentile, Hani Jneid, et al. “2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease.” Journal of the American College of Cardiology 77, no. 4 (February 2, 2021): E25-+.

Scholars@Duke

Zeitler, Emily P., Lauren B. Cooper, Robert M. Clare, Karen Chiswell, Angela Lowenstern, Joseph G. Rogers, Carmelo A. Milano, Jacob N. Schroder, Sana M. Al-Khatib, and Robert J. Mentz. “OptiVol for Volume Assessment in Patients With Continuous Flow Left Ventricular Assist Device.” Asaio J 67, no. 2 (February 1, 2021): 192–95. https://doi.org/10.1097/MAT.0000000000001244.

PMID
33512914
Full Text

Pages