Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Pun, Patrick H., Craig S. Parzynski, Daniel J. Friedman, Gillian Sanders, Jeptha P. Curtis, and Sana M. Al-Khatib. “Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis.” Clin J Am Soc Nephrol 15, no. 11 (November 6, 2020): 1622–30. https://doi.org/10.2215/CJN.07920520.

PMID
32967922
Full Text

Chery, Godefroy, Nicholas Kamp, Andrzej S. Kosinski, Gillian Sanders Schmidler, Renato D. Lopes, Manesh Patel, and Sana M. Al-Khatib. “Prognostic value of myocardial fibrosis on cardiac magnetic resonance imaging in patients with ischemic cardiomyopathy: A systematic review.” American Heart Journal 229 (November 2020): 52–60. https://doi.org/10.1016/j.ahj.2020.08.004.

PMID
32916608
Full Text

Ganesh, Arun, Yawar J. Qadri, Richard L. Boortz-Marx, Sana M. Al-Khatib, David H. Harpole, Jason N. Katz, Jason I. Koontz, et al. “Stellate Ganglion Blockade: an Intervention for the Management of Ventricular Arrhythmias.” Curr Hypertens Rep 22, no. 12 (October 23, 2020): 100. https://doi.org/10.1007/s11906-020-01111-8.

PMID
33097982
Full Text

Goldstein, Sarah A., Shuang Li, Di Lu, Roland A. Matsouaka, Jennifer Rymer, Gregg C. Fonarow, James A. de Lemos, et al. “Implantable Cardioverter Defibrillator Utilization and Mortality Among Patients ≥ 65 Years of Age with a Low Ejection Fraction Following Coronary Revascularization.” Am J Cardiol, October 14, 2020. https://doi.org/10.1016/j.amjcard.2020.09.056.

PMID
33068540
Full Text

Al-Khatib, Sana M., Vanessa Blumer, and G Michael Felker. “Medications Are Important for Sudden Cardiac Death Prevention But So Is the Implantable Cardioverter-Defibrillator.” Jacc Heart Fail 8, no. 10 (October 2020): 856–58. https://doi.org/10.1016/j.jchf.2020.07.003.

PMID
32919913
Full Text

Carnicelli, Anthony P., Sana M. Al-Khatib, Denis Xavier, Frederik Dalgaard, Peter D. Merrill, Daniel M. Wojdyla, Basil S. Lewis, et al. “Premature permanent discontinuation of apixaban or warfarin in patients with atrial fibrillation.” Heart, September 16, 2020. https://doi.org/10.1136/heartjnl-2020-317229.

PMID
32938772
Full Text

Bennett, Antonia V., Mattias Jonsson, Ronald C. Chen, Sana M. Al-Khatib, Kevin P. Weinfurt, and Lesley H. Curtis. “Applying patient-reported outcome methodology to capture patient-reported health data: Report from an NIH Collaboratory roundtable.” Healthc (Amst) 8, no. 3 (September 2020): 100442. https://doi.org/10.1016/j.hjdsi.2020.100442.

PMID
32919581
Full Text

Rasmussen, Peter Vibe, Jannik Langtved Pallisgaard, Morten Lock Hansen, Gunnar Hilmar Gislason, Christian Torp-Pedersen, Martin Ruwald, Karen P. Alexander, Renato D. Lopes, Sana M. Al-Khatib, and Frederik Dalgaard. “Treatment of Older Patients with Atrial Fibrillation by Morbidity Burden.” Eur Heart J Qual Care Clin Outcomes, August 28, 2020. https://doi.org/10.1093/ehjqcco/qcaa070.

PMID
32857834
Full Text

Zeitler, Emily P., Sana M. Al-Khatib, Rebecca Yapejian, Connor C. Tripp, and Samuel F. Sears. “Regulation Without Representation: Cardiac Device Patient Knowledge and Attitudes About the FDA Regulatory Process.” Circulation. Arrhythmia and Electrophysiology 13, no. 8 (August 2020): e008561. https://doi.org/10.1161/circep.120.008561.

PMID
32628518
Full Text

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