Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Zeitler, Emily P., Sana M. Al-Khatib, Rebecca Yapejian, Connor C. Tripp, and Samuel F. Sears. “Regulation Without Representation: Cardiac Device Patient Knowledge and Attitudes About the FDA Regulatory Process.” Circ Arrhythm Electrophysiol 13, no. 8 (August 2020): e008561. https://doi.org/10.1161/CIRCEP.120.008561.

PMID
32628518
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Ding, Eric Y., Emma Svennberg, Christina Wurster, David Duncker, Martin Manninger, Steven A. Lubitz, Emily Dickson, et al. “Survey of current perspectives on consumer-available digital health devices for detecting atrial fibrillation.” Cardiovasc Digit Health J 1, no. 1 (July 2020): 21–29. https://doi.org/10.1016/j.cvdhj.2020.06.002.

PMID
32924024
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Sharma, Abhinav, Jingjing Wu, Haolin Xu, Adrian Hernandez, G Michael Felker, Sana Al-Khatib, Jennifer Green, et al. “Comparative Effectiveness of Primary Prevention Implantable Cardioverter-Defibrillators in Older Heart Failure Patients With Diabetes Mellitus.” J Am Heart Assoc 9, no. 12 (June 16, 2020): e012405. https://doi.org/10.1161/JAHA.119.012405.

PMID
32476539
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Al-Khatib, Sana M., Emelia J. Benjamin, Christine M. Albert, Alvaro Alonso, Cynthia Chauhan, Peng-Sheng Chen, Anne B. Curtis, et al. “Advancing Research on the Complex Interrelations Between Atrial Fibrillation and Heart Failure: A Report From a US National Heart, Lung, and Blood Institute Virtual Workshop.” Circulation 141, no. 23 (June 9, 2020): 1915–26. https://doi.org/10.1161/CIRCULATIONAHA.119.045204.

PMID
32511001
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Fudim, Marat, Fatima Ali-Ahmed, Craig S. Parzynski, Andrew P. Ambrosy, Daniel J. Friedman, Sean D. Pokorney, Jeptha P. Curtis, et al. “Periprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure.” Jama Cardiol 5, no. 6 (June 1, 2020): 643–51. https://doi.org/10.1001/jamacardio.2020.0391.

PMID
32211811
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Fudim, Marat, Matthew A. Carlisle, Srikant Devaraj, Tarek Ajam, Andrew P. Ambrosy, Sean D. Pokorney, Sana M. Al-Khatib, and Masoor Kamalesh. “One-year mortality after implantable cardioverter-defibrillator placement within the Veterans Affairs Health System.” Eur J Heart Fail 22, no. 5 (May 2020): 859–67. https://doi.org/10.1002/ejhf.1755.

PMID
32108984
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Fudim, Marat, Frederik Dalgaard, Sana M. Al-Khatib, Daniel J Friedman, Kathryn Lallinger, William T. Abraham, John G. F. Cleland, et al. “Future research prioritization in cardiac resynchronization therapy.” Am Heart J 223 (May 2020): 48–58. https://doi.org/10.1016/j.ahj.2020.02.011.

PMID
32163753
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Torp-Pedersen, Christian, Andreas Goette, Peter Bronnum Nielsen, Tatjana Potpara, Laurent Fauchier, Alan John Camm, Elena Arbelo, et al. “'Real-world' observational studies in arrhythmia research: data sources, methodology, and interpretation. A position document from European Heart Rhythm Association (EHRA), endorsed by Heart Rhythm Society (HRS), Asia-Pacific HRS (APHRS), and Latin America HRS (LAHRS).” Europace 22, no. 5 (May 1, 2020): 831–32. https://doi.org/10.1093/europace/euz210.

PMID
31725156
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Goldstein, Sarah, Di Lu, Roland Matsouaka, Tracy Wang, Jennifer Rymer, Sean Pokorney, and Sana M. Al-Khatib. “IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR (ICD) UTILIZATION AMONG OLDER PATIENTS WITH LOW EJECTION FRACTION FOLLOWING CORONARY REVASCULARIZATION FOR MYOCARDIAL INFARCTION.” In Journal of the American College of Cardiology, 75:379–379. ELSEVIER SCIENCE INC, 2020.

Scholars@Duke

Cronin, Edmond M., Frank M. Bogun, Philippe Maury, Petr Peichl, Minglong Chen, Narayanan Namboodiri, Luis Aguinaga, et al. “2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias: executive summary.” Europace 22, no. 3 (March 1, 2020): 450–95. https://doi.org/10.1093/europace/euz332.

PMID
31995197
Full Text

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