Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Peterson, BE, Al-Khatib, SM, and Granger, CB. "Apixaban to prevent stroke in patients with atrial fibrillation: a review." Therapeutic advances in cardiovascular disease 11, no. 3 (March 2017): 91-104. (Review)

PMID
27342651
Full Text

Al-Khatib, SM, and Page, RL. "Ongoing Management of Patients With Supraventricular Tachycardia." JAMA cardiology 2, no. 3 (March 2017): 332-333.

PMID
28030653
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Pun, PH, Sheng, S, Sanders, G, DeVore, AD, Friedman, D, Fonarow, GC, Heidenreich, PA, Yancy, CW, Hernandez, AF, and Al-Khatib, SM. "Prescription of Guideline-Recommended Implantable Cardioverter Defibrillator and Cardiac Resynchronization Therapy Among Patients Hospitalized With Heart Failure and Varying Degrees of Renal Function." The American journal of cardiology 119, no. 6 (March 2017): 886-892.

PMID
28160975
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Rao, MP, Al-Khatib, SM, Pokorney, SD, She, L, Romanov, A, Nicolau, JC, Lee, KL, Carson, P, Selzman, CH, Stepinska, J, Cleland, JGF, Tungsubutra, W, Desvigne-Nickens, PM, Sueta, CA, Siepe, M, Lang, I, Feldman, AM, Yii, M, Rouleau, JL, Velazquez, EJ, and STICH Trial Investigators, . "Sudden Cardiac Death in Patients With Ischemic Heart Failure Undergoing Coronary Artery Bypass Grafting: Results From the STICH Randomized Clinical Trial (Surgical Treatment for Ischemic Heart Failure)." Circulation 135, no. 12 (March 2017): 1136-1144.

PMID
28154006
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Betz, JK, Katz, DF, Peterson, PN, Borne, RT, Al-Khatib, SM, Wang, Y, Hansen, CM, McManus, DD, Mathew, JS, and Masoudi, FA. "Outcomes Among Older Patients Receiving Implantable Cardioverter-Defibrillators for Secondary Prevention: From the NCDR ICD Registry (vol 69, pg 265, 2017)." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 69, no. 8 (February 28, 2017): 1102-1102.

Full Text

Al-Khatib, SM, Yancy, CW, Solis, P, Becker, L, Benjamin, EJ, Carrillo, RG, Ezekowitz, JA, Fonarow, GC, Kantharia, BK, Kleinman, M, Nichol, G, and Varosy, PD. "2016 AHA/ACC Clinical Performance and Quality Measures for Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures." Journal of the American College of Cardiology 69, no. 6 (February 2017): 712-744.

PMID
28007322
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Guimarães, PO, Wojdyla, DM, Alexander, JH, Thomas, L, Alings, M, Flaker, GC, Al-Khatib, SM, Hanna, M, Horowitz, JD, Wallentin, L, Granger, CB, and Lopes, RD. "Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial." International Journal of Cardiology 227 (January 2017): 443-449.

PMID
27852444
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Katz, DF, Peterson, P, Borne, RT, Betz, J, Al-Khatib, SM, Varosy, PD, Wang, Y, Hsu, JC, Hoffmayer, KS, Kipp, RT, Hansen, CM, Turakhia, MP, and Masoudi, FA. "Survival After Secondary Prevention Implantable Cardioverter-Defibrillator Placement: An Analysis From the NCDR ICD Registry." Jacc. Clinical Electrophysiology 3, no. 1 (January 2017): 20-28.

PMID
29759690
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Pokorney, SD, Miller, AL, Chen, AY, Thomas, L, Fonarow, GC, de Lemos, JA, Al-Khatib, SM, Velazquez, EJ, Peterson, ED, and Wang, TY. "Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction." Circulation 135, no. 1 (January 2017): 38-47.

PMID
27881561
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Al-Khatib, SM, Yancy, CW, Solis, P, Becker, L, Benjamin, EJ, Carrillo, RG, Ezekowitz, JA, Fonarow, GC, Kantharia, BK, Kleinman, M, Nichol, G, and Varosy, PD. "2016 AHA/ACC Clinical Performance and Quality Measures for Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures." Circulation. Cardiovascular Quality and Outcomes 10, no. 1 (January 2017): e000022-null. (Review)

PMID
27993943
Full Text

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