Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address palme002@mc.duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Smith, PJ, Snyder, LD, Palmer, SM, Hoffman, BM, Stonerock, GL, Ingle, KK, Saulino, CK, and Blumenthal, JA. "Depression, social support, and clinical outcomes following lung transplantation: a single-center cohort study. (Accepted)" Transplant international : official journal of the European Society for Organ Transplantation 31, no. 5 (May 2018): 495-502.

PMID
29130541
Full Text

Smith, PJ, Blumenthal, JA, Hoffman, BM, Davis, RD, and Palmer, SM. "Postoperative cognitive dysfunction and mortality following lung transplantation." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18, no. 3 (March 2018): 696-703.

PMID
29087035
Full Text

Choi, KJ, Cheng, TZ, Honeybrook, AL, Gray, AL, Snyder, LD, Palmer, SM, Abi Hachem, R, and Jang, DW. "Correlation between sinus and lung cultures in lung transplant patients with cystic fibrosis." International forum of allergy & rhinology 8, no. 3 (March 2018): 389-393.

PMID
29240302
Full Text

Riley, IL, Boulware, LE, Sun, J-L, Chiswell, K, Que, LG, Kraft, M, Todd, JL, Palmer, SM, and Anderson, ML. "Factors associated with reporting results for pulmonary clinical trials in ClinicalTrials.gov." Clinical trials (London, England) 15, no. 1 (February 2018): 87-94.

PMID
29121787
Full Text

Ali, HA, Pavlisko, EN, Snyder, LD, Frank, M, and Palmer, SM. "Complement system in Lung Transplantation." Clinical transplantation (January 23, 2018). (Review)

PMID
29374425
Full Text

Cantu, E, Diamond, JM, Suzuki, Y, Lasky, J, Schaufler, C, Lim, B, Shah, R, Porteous, M, Lederer, DJ, Kawut, SM, Palmer, SM, Snyder, LD, Hartwig, MG, Lama, VN, Bhorade, S, Bermudez, C, Crespo, M, McDyer, J, Wille, K, Orens, J, Shah, PD, Weinacker, A, Weill, D, Wilkes, D, Roe, D, Hage, C, Ware, LB, Bellamy, SL, Christie, JD, and Lung Transplant Outcomes Group, . "Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant." American journal of respiratory and critical care medicine 197, no. 2 (January 2018): 235-243.

PMID
28872353
Full Text

Ardini-Poleske, ME, Clark, RF, Ansong, C, Carson, JP, Corley, RA, Deutsch, GH, Hagood, JS, Kaminski, N, Mariani, TJ, Potter, SS, Pryhuber, GS, Warburton, D, Whitsett, JA, Palmer, SM, Ambalavanan, N, and LungMAP Consortium, . "LungMAP: The Molecular Atlas of Lung Development Program." American journal of physiology. Lung cellular and molecular physiology 313, no. 5 (November 2017): L733-L740. (Review)

PMID
28798251
Full Text

Porteous, MK, Lee, JC, Lederer, DJ, Palmer, SM, Cantu, E, Shah, RJ, Bellamy, SL, Lama, VN, Bhorade, SM, Crespo, MM, McDyer, JF, Wille, KM, Localio, AR, Orens, JB, Shah, PD, Weinacker, AB, Arcasoy, S, Wilkes, DS, Ware, LB, Christie, JD, Kawut, SM, Diamond, JM, and Lung Transplant Outcomes Group, . "Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension." Annals of the American Thoracic Society 14, no. 10 (October 2017): 1514-1522.

PMID
28719755
Full Text

Belperio, J, Palmer, SM, and Weigt, SS. "Host-Pathogen Interactions and Chronic Lung Allograft Dysfunction." Annals of the American Thoracic Society 14, no. Supplement_3 (September 2017): S242-S246.

PMID
28945471
Full Text

Brass, DM, Nagler, AE, Weinberg, K, Kelly, FL, and Palmer, SM. "Diacetyl, Epithelial Injury and Popcorn Lung." September 2017.

Scholars@Duke

Pages