Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Professor in Population Health Sciences
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Grants

Weight
-20

Publications

Anderson, Michaela R., Jayaram K. Udupa, Ethan Edwin, Joshua M. Diamond, Jonathan P. Singer, Jasleen Kukreja, Steven R. Hays, et al. “Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study..” J Heart Lung Transplant 38, no. 12 (December 2019): 1246–56. https://doi.org/10.1016/j.healun.2019.08.013.

PMID
31474492
Full Text

Durheim, Michael T., Jennifer Judy, Shaun Bender, Dorothy Baumer, Joseph Lucas, Scott B. Robinson, Omar Mohamedaly, et al. “In-Hospital Mortality in Patients with Idiopathic Pulmonary Fibrosis: A US Cohort Study..” Lung 197, no. 6 (December 2019): 699–707. https://doi.org/10.1007/s00408-019-00270-z.

PMID
31541276
Full Text

Anderson, Michaela R., Nicholas A. Kolaitis, Ying Gao, Jasleen Kukreja, John Greenland, Steven Hays, Paul Wolters, et al. “A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates..” Am J Transplant 19, no. 11 (November 2019): 3155–61. https://doi.org/10.1111/ajt.15525.

PMID
31278829
Full Text

Martinu, Tereza, William C. McManigle, Francine L. Kelly, Margaret E. Nelson, Jesse Sun, Helen L. Zhang, Jay K. Kolls, Kymberly M. Gowdy, and Scott M. Palmer. “IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease..” Transplantation 103, no. 11 (November 2019): 2264–74. https://doi.org/10.1097/TP.0000000000002837.

PMID
31658231
Full Text

Todd, Jamie L., Megan L. Neely, Robert Overton, Katey Durham, Mridu Gulati, Howard Huang, Jesse Roman, et al. “Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry..” Respir Res 20, no. 1 (October 22, 2019). https://doi.org/10.1186/s12931-019-1190-z.

PMID
31640794
Full Text

Swaminathan, Aparna C., Megan L. Neely, Courtney W. Frankel, Fran L. Kelly, Slavé Petrovski, Michael T. Durheim, Erika Bush, et al. “Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants..” In Chest, 156:477–85, 2019. https://doi.org/10.1016/j.chest.2019.03.030.

PMID
30978332
Full Text

Weigt, S Samuel, Xiaoyan Wang, Vyacheslav Palchevskiy, Xinmin Li, Naman Patel, David J. Ross, John Reynolds, et al. “Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection..” J Heart Lung Transplant 38, no. 8 (August 2019): 845–55. https://doi.org/10.1016/j.healun.2019.05.001.

PMID
31122726
Full Text

Cheng, Tracy Z., Kevin J. Choi, Adam L. Honeybrook, Rasheedat T. Zakare-Fagbamila, Alice L. Gray, Laurie D. Snyder, Scott M. Palmer, Ralph Abi-Hachem, and David W. Jang. “Decreased Antibiotic Utilization After Sinus Surgery in Cystic Fibrosis Patients With Lung Transplantation..” Am J Rhinol Allergy 33, no. 4 (July 2019): 354–58. https://doi.org/10.1177/1945892419830624.

PMID
30781973
Full Text

Kelly, Francine L., Kaitlyn E. Weinberg, Andrew E. Nagler, Andrew B. Nixon, Mark D. Star, Jamie L. Todd, David M. Brass, and Scott M. Palmer. “EGFR-Dependent IL8 Production by Airway Epithelial Cells After Exposure to the Food Flavoring Chemical 2,3-Butanedione..” Toxicol Sci 169, no. 2 (June 1, 2019): 534–42. https://doi.org/10.1093/toxsci/kfz066.

PMID
30851105
Full Text

Snyder, Laurie, Megan L. Neely, Anne S. Hellkamp, Emily O’Brien, Joao de Andrade, Craig S. Conoscenti, Thomas Leonard, et al. “Predictors of death or lung transplant after a diagnosis of idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry..” Respir Res 20, no. 1 (May 30, 2019). https://doi.org/10.1186/s12931-019-1043-9.

PMID
31142314
Full Text

Pages