Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Palmer, SM, Snyder, L, Todd, JL, Soule, B, Christian, R, Anstrom, K, Luo, Y, Gagnon, R, and Rosen, G. "Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis." Chest (September 7, 2018).

PMID
30201408
Full Text

Clausen, ES, Snyder, LD, Palmer, SM, Gray, A, and Smith, PJ. "EFFECT OF WEIGHT GAIN PRE-LUNG TRANSPLANT IN RECIPIENTS WITH CYSTIC FIBROSIS.": WILEY, September 1, 2018.

Scholars@Duke

Clausen, ES, Snyder, LD, Palmer, SM, Gray, A, and Smith, PJ. "EFFECT OF WEIGHT GAIN PRE-LUNG TRANSPLANT IN RECIPIENTS WITH CYSTIC FIBROSIS.": WILEY, September 1, 2018.

Scholars@Duke

Clausen, ES, Frankel, C, Palmer, SM, Snyder, LD, and Smith, PJ. "Pre-transplant weight loss and clinical outcomes after lung transplantation." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation (July 29, 2018).

PMID
30228085
Full Text

Tambur, AR, Campbell, P, Claas, FH, Feng, S, Gebel, HM, Jackson, AM, Mannon, RB, Reed, EF, Tinckam, K, Askar, M, Chandraker, A, Chang, PP, Colvin, M, Demetris, A-J, Diamond, JM, Dipchand, AI, Fairchild, RL, Ford, ML, Friedewald, J, Gill, RG, Glotz, D, Goldberg, H, Hachem, R, Knechtle, S, Kobashigawa, J, Levine, DJ, Levitsky, J, Mengel, M, Milford, E, Newell, KA, O'Leary, JG, Palmer, S, Randhawa, P, Smith, J, Snyder, L, Starling, RC, Sweet, S, Taner, T, Taylor, CJ, Woodle, S, Zeevi, A, and Nickerson, P. "Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18, no. 7 (July 2018): 1604-1614.

PMID
29603613
Full Text

Weigt, SS, Wang, X, Palchevskiy, V, Patel, N, Derhovanessian, A, Shino, MY, Sayah, DM, Lynch, JP, Saggar, R, Ross, DJ, Kubak, BM, Ardehali, A, Palmer, S, Husain, S, and Belperio, JA. "Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft." Transplantation 102, no. 6 (June 2018): 986-993.

PMID
29256975
Full Text

Hulbert, AL, Pavlisko, EN, and Palmer, SM. "Current challenges and opportunities in the management of antibody-mediated rejection in lung transplantation." Current Opinion in Organ Transplantation 23, no. 3 (June 2018): 308-315.

PMID
29742565
Full Text

Smith, PJ, Snyder, LD, Palmer, SM, Hoffman, BM, Stonerock, GL, Ingle, KK, Saulino, CK, and Blumenthal, JA. "Depression, social support, and clinical outcomes following lung transplantation: a single-center cohort study." Transplant International : Official Journal of the European Society for Organ Transplantation 31, no. 5 (May 2018): 495-502.

PMID
29130541
Full Text

Todd, JL, Venkat, V, Henao, R, Brinkley, C, Kelly, FL, Frankel, CW, Frear, A, Moseley, MA, Thompson, JW, Belperio, JA, Budev, M, Shah, PD, Singer, LG, Reynolds, JM, Foster, MW, and Palmer, SM. "Bronchoalveolar Lavage Fluid Proteome in Chronic Lung Allograft Dysfunction." 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT). Nice, FRANCE. April 11, 2018 - April 14, 2018.: ELSEVIER SCIENCE INC, April 1, 2018.

Scholars@Duke

Ali, HA, Pavlisko, EN, Snyder, LD, Frank, M, and Palmer, SM. "Complement system in lung transplantation." Clinical Transplantation 32, no. 4 (April 2018): e13208-e13208. (Review)

PMID
29374425
Full Text

Pages