Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Professor in Population Health Sciences
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Mosher, Christopher L., Jeremy M. Weber, Courtney W. Frankel, Megan L. Neely, and Scott M. Palmer. “Risk factors for mortality in lung transplant recipients aged ≥65 years: A retrospective cohort study of 5,815 patients in the scientific registry of transplant recipients.” J Heart Lung Transplant 40, no. 1 (January 2021): 42–55. https://doi.org/10.1016/j.healun.2020.10.009.

PMID
33208278
Full Text

Durheim, Michael T., Jennifer Judy, Shaun Bender, Megan L. Neely, Dorothy Baumer, Scott B. Robinson, Craig S. Conoscenti, Thomas B. Leonard, Howard M. Lazarus, and Scott M. Palmer. “A retrospective study of in-hospital mortality in patients with idiopathic pulmonary fibrosis between 2015 and 2018.” Medicine (Baltimore) 99, no. 47 (November 20, 2020): e23143. https://doi.org/10.1097/MD.0000000000023143.

PMID
33217820
Full Text

Chu, Michael C., Patrick J. Smith, John M. Reynolds, Scott M. Palmer, Laurie D. Snyder, Alice L. Gray, and James A. Blumenthal. “Depression, Immunosuppressant Levels, and Clinical Outcomes in Postlung Transplant Recipients.” Int J Psychiatry Med 55, no. 6 (November 2020): 421–36. https://doi.org/10.1177/0091217420906637.

PMID
32052665
Full Text

Salisbury, Margaret L., Craig S. Conoscenti, Daniel A. Culver, Eric Yow, Megan L. Neely, Shaun Bender, Nadine Hartmann, Scott M. Palmer, Thomas B. Leonard, and Thomas B. IPF-PRO Registry principal investigators as follows. “Antifibrotic Drug Use in Patients with Idiopathic Pulmonary Fibrosis. Data from the IPF-PRO Registry.” Ann Am Thorac Soc 17, no. 11 (November 2020): 1413–23. https://doi.org/10.1513/AnnalsATS.201912-880OC.

PMID
32574517
Full Text

Al-Naamani, Nadine, Hao-Min Pan, Michaela R. Anderson, Drew A. Torigian, Yubing Tong, Michelle Oyster, Mary K. Porteous, et al. “Thoracic Visceral Adipose Tissue Area and Pulmonary Hypertension in Lung Transplant Candidates. The Lung Transplant Body Composition Study.” Ann Am Thorac Soc 17, no. 11 (November 2020): 1393–1400. https://doi.org/10.1513/AnnalsATS.202003-247OC.

PMID
32530703
Full Text

Eichenberger, Emily M., Felicia Ruffin, Michael Dagher, Reginald Lerebours, Sin-Ho Jung, Batu Sharma-Kuinkel, Andrew N. Macintyre, et al. “Bacteremia in solid organ transplant recipients as compared to immunocompetent patients: Acute phase cytokines and outcomes in a prospective, matched cohort study.” Am J Transplant, October 31, 2020. https://doi.org/10.1111/ajt.16388.

PMID
33131212
Full Text

Halpern, Samantha E., Alec McConnell, Sarah B. Peskoe, Vignesh Raman, Oliver K. Jawitz, Ashley Y. Choi, Megan L. Neely, Scott M. Palmer, and Matthew G. Hartwig. “A three-tier system for evaluation of organ procurement organizations' willingness to pursue and utilize nonideal donor lungs.” Am J Transplant, October 13, 2020. https://doi.org/10.1111/ajt.16347.

PMID
33048423
Full Text

Neely, Megan L., Scott M. Palmer, and Laurie D. Snyder. “Primary graft dysfunction and health-related quality of life after transplantation: The good, the bad, and the missing.” Am J Transplant, September 21, 2020. https://doi.org/10.1111/ajt.16313.

PMID
32957167
Full Text

Zhang, Chen Yang Kevin, Musawir Ahmed, Ella Huszti, Liran Levy, Sarah E. Hunter, Kristen M. Boonstra, Sajad Moshkelgosha, et al. “Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration.” J Heart Lung Transplant 39, no. 9 (September 2020): 934–44. https://doi.org/10.1016/j.healun.2020.05.006.

PMID
32487471
Full Text

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