Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Professor in Population Health Sciences
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Chu, Michael C., Patrick J. Smith, John M. Reynolds, Scott M. Palmer, Laurie D. Snyder, Alice L. Gray, and James A. Blumenthal. “Depression, Immunosuppressant Levels, and Clinical Outcomes in Postlung Transplant Recipients.” Int J Psychiatry Med 55, no. 6 (November 2020): 421–36. https://doi.org/10.1177/0091217420906637.

PMID
32052665
Full Text

Halpern, Samantha E., Alec McConnell, Sarah B. Peskoe, Vignesh Raman, Oliver K. Jawitz, Ashley Y. Choi, Megan L. Neely, Scott M. Palmer, and Matthew G. Hartwig. “A Three-Tier System for Evaluation of Organ Procurement Organizations' Willingness to Pursue and Utilize Non-Ideal Donor Lungs.” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, October 13, 2020. https://doi.org/10.1111/ajt.16347.

PMID
33048423
Full Text

Neely, Megan L., Scott M. Palmer, and Laurie D. Snyder. “Primary graft dysfunction and health-related quality of life after transplantation: The good, the bad, and the missing.” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, September 21, 2020. https://doi.org/10.1111/ajt.16313.

PMID
32957167
Full Text

Zhang, Chen Yang Kevin, Musawir Ahmed, Ella Huszti, Liran Levy, Sarah E. Hunter, Kristen M. Boonstra, Sajad Moshkelgosha, et al. “Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration.” J Heart Lung Transplant 39, no. 9 (September 2020): 934–44. https://doi.org/10.1016/j.healun.2020.05.006.

PMID
32487471
Full Text

Anderson, Michaela R., Imaani Easthausen, Grace Gallagher, Jayaram Udupa, Yubing Tong, Drew Torigian, Joshua Matthew Diamond, et al. “Skeletal muscle adiposity and outcomes in candidates for lung transplantation: a lung transplant body composition cohort study.” Thorax 75, no. 9 (September 2020): 801–4. https://doi.org/10.1136/thoraxjnl-2019-214461.

PMID
32482837
Full Text

Todd, Jamie L., Megan L. Neely, Heather Kopetskie, Michelle L. Sever, Jerry Kirchner, Courtney W. Frankel, Laurie D. Snyder, et al. “Risk Factors for Acute Rejection in the First Year after Lung Transplant. A Multicenter Study.” Am J Respir Crit Care Med 202, no. 4 (August 15, 2020): 576–85. https://doi.org/10.1164/rccm.201910-1915OC.

PMID
32379979
Full Text

Gohir, Wajiha, William Klement, Lianne G. Singer, Scott M. Palmer, Tony Mazzulli, Shaf Keshavjee, and Shahid Husain. “Identifying host microRNAs in bronchoalveolar lavage samples from lung transplant recipients infected with Aspergillus.” J Heart Lung Transplant, July 25, 2020. https://doi.org/10.1016/j.healun.2020.07.014.

PMID
32771440
Full Text

Salisbury, Margaret L., Craig S. Conoscenti, Daniel A. Culver, Eric Yow, Megan L. Neely, Shaun Bender, Nadine Hartmann, Scott M. Palmer, Thomas B. Leonard, and Thomas B. IPF-PROTM Registry investigators. “Antifibrotic Drug Use in Patients with IPF: Data from the IPF-PRO Registry.” Ann Am Thorac Soc, June 23, 2020. https://doi.org/10.1513/AnnalsATS.201912-880OC.

PMID
32574517
Full Text

Fan, Yanni, Shaun D. Bender, Craig S. Conoscenti, Linda Davidson-Ray, Patricia A. Cowper, Scott M. Palmer, Joao A. de Andrade, and Joao A. IPF-PRO Registry Investigators. “Hospital-Based Resource Use and Costs Among Patients With Idiopathic Pulmonary Fibrosis Enrolled in the Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry.” Chest 157, no. 6 (June 2020): 1522–30. https://doi.org/10.1016/j.chest.2019.12.041.

PMID
32004554
Full Text

Case, Amy Hajari, Anne S. Hellkamp, Megan L. Neely, Shaun Bender, Daniel F. Dilling, Mridu Gulati, David L. Hotchkin, et al. “Associations between Patient-reported Outcomes and Death or Lung Transplant in Idiopathic Pulmonary Fibrosis. Data from the Idiopathic Pulmonary Fibrosis Prospective Outcomes Registry.” Ann Am Thorac Soc 17, no. 6 (June 2020): 699–705. https://doi.org/10.1513/AnnalsATS.201906-437OC.

PMID
32040340
Full Text

Pages