Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Professor in Population Health Sciences
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Glanville, Allan R., Geert M. Verleden, Jamie L. Todd, Christian Benden, Fiorella Calabrese, Jens Gottlieb, Ramsey R. Hachem, et al. “Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome-A consensus report from the Pulmonary Council of the ISHLT..” J Heart Lung Transplant 38, no. 5 (May 2019): 483–92. https://doi.org/10.1016/j.healun.2019.03.008.

PMID
31027539
Full Text

Swaminathan, Aparna C., Megan L. Neely, Courtney W. Frankel, Fran L. Kelly, Slavé Petrovski, Michael T. Durheim, Erika Bush, et al. “Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants..” In Chest, 2019. https://doi.org/10.1016/j.chest.2019.03.030.

PMID
30978332
Full Text

Cheng, Tracy Z., Kevin J. Choi, Adam L. Honeybrook, Rasheedat T. Zakare-Fagbamila, Alice L. Gray, Laurie D. Snyder, Scott M. Palmer, Ralph Abi-Hachem, and David W. Jang. “Decreased Antibiotic Utilization After Sinus Surgery in Cystic Fibrosis Patients With Lung Transplantation..” American Journal of Rhinology & Allergy, February 20, 2019. https://doi.org/10.1177/1945892419830624.

PMID
30781973
Full Text

Li, Wenjun, Jason M. Gauthier, Ryuji Higashikubo, Hsi-Min Hsiao, Satona Tanaka, Linh Vuong, Jon H. Ritter, et al. “Bronchus-associated lymphoid tissue-resident Foxp3+ T lymphocytes prevent antibody-mediated lung rejection..” J Clin Invest 129, no. 2 (February 1, 2019): 556–68. https://doi.org/10.1172/JCI122083.

PMID
30561386
Full Text

Todd, Jamie L., Megan L. Neely, C. A. Finlen Copeland, Courtney W. Frankel, John M. Reynolds, and Scott M. Palmer. “Prognostic significance of early pulmonary function changes after onset of chronic lung allograft dysfunction..” The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation 38, no. 2 (February 2019): 184–93. https://doi.org/10.1016/j.healun.2018.10.006.

PMID
30466803
Full Text

Clausen, Emily Siu, Courtney Frankel, Scott M. Palmer, Laurie D. Snyder, and Patrick J. Smith. “Pre-transplant weight loss and clinical outcomes after lung transplantation..” The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation 37, no. 12 (December 2018): 1443–47. https://doi.org/10.1016/j.healun.2018.07.015.

PMID
30228085
Full Text

Palmer, Scott M., Laurie Snyder, Jamie L. Todd, Benjamin Soule, Rose Christian, Kevin Anstrom, Yi Luo, Robert Gagnon, and Glenn Rosen. “Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis..” Chest 154, no. 5 (November 2018): 1061–69. https://doi.org/10.1016/j.chest.2018.08.1058.

PMID
30201408
Full Text

Clausen, E. S., L. D. Snyder, S. M. Palmer, A. Gray, and P. J. Smith. “EFFECT OF WEIGHT GAIN PRE-LUNG TRANSPLANT IN RECIPIENTS WITH CYSTIC FIBROSIS.” In Pediatric Pulmonology, 53:352–53. WILEY, 2018.

Scholars@Duke

Clausen, E. S., L. D. Snyder, S. M. Palmer, A. Gray, and P. J. Smith. “EFFECT OF WEIGHT GAIN PRE-LUNG TRANSPLANT IN RECIPIENTS WITH CYSTIC FIBROSIS.” In Pediatric Pulmonology, 53:352–53. WILEY, 2018.

Scholars@Duke

Tambur, Anat R., Patricia Campbell, Frans H. Claas, Sandy Feng, Howard M. Gebel, Annette M. Jackson, Roslyn B. Mannon, et al. “Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report..” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18, no. 7 (July 2018): 1604–14. https://doi.org/10.1111/ajt.14752.

PMID
29603613
Full Text

Pages