
Education and Training
- Ph.D., Duke University, 2002
Li, Angus, Samuel Liu, Rennica Huang, Seungkirl Ahn, and Robert J. Lefkowitz. “Loss of Biased Signaling Specificity of the Angiotensin II Type 1 Receptor in Overexpressed Systems.” Faseb J 36 Suppl 1 (May 2022). https://doi.org/10.1096/fasebj.2022.36.S1.R2797.
Pani, B., S. Ahn, P. K. Rambarfat, S. Vege, A. W. Kahsai, A. Liu, B. N. Valan, D. P. Status, T. Costa, and R. J. Lefkowitz. “Unique Positive Cooperativity Between the beta-Arrestin-Biased beta-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the beta 2-Adrenergic Receptor (vol 100, pg 513, 2021).” Molecular Pharmacology 100, no. 6 (December 1, 2021): 597–597.
Wang, Jialu, Biswaranjan Pani, Ilhan Gokhan, Xinyu Xiong, Alem W. Kahsai, Haoran Jiang, Seungkirl Ahn, Robert J. Lefkowitz, and Howard A. Rockman. “β-Arrestin-Biased Allosteric Modulator Potentiates Carvedilol-Stimulated β Adrenergic Receptor Cardioprotection.” Mol Pharmacol 100, no. 6 (December 2021): 568–79. https://doi.org/10.1124/molpharm.121.000359.
“Correction to "Unique Positive Cooperativity Between the β-Arrestin-Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor".” Mol Pharmacol 100, no. 6 (December 2021): 597. https://doi.org/10.1124/molpharm.121.000363err.
Pani, Biswaranjan, Seungkirl Ahn, Paula K. Rambarat, Shashank Vege, Alem W. Kahsai, Andrew Liu, Bruno N. Valan, Dean P. Staus, Tommaso Costa, and Robert J. Lefkowitz. “Unique Positive Cooperativity Between the β-Arrestin-Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor.” Mol Pharmacol 100, no. 5 (November 2021): 513–25. https://doi.org/10.1124/molpharm.121.000363.
Ahn, Seungkirl, Sudha K. Shenoy, Louis M. Luttrell, and Robert J. Lefkowitz. “SnapShot: β-Arrestin Functions.” Cell 182, no. 5 (September 3, 2020): 1362-1362.e1. https://doi.org/10.1016/j.cell.2020.07.034.
Wang, Jialu, Ilhan Gokhan, Xinyu Xiong, Alem W. Kahsai, Haoran Jiang, Conrad T. Pfeiffer, William Tian, et al. “Abstract MP133: Development of β-arrestin-biased Positive Allosteric Modulators for the β
1
Adrenergic Receptor.” In Circulation Research, Vol. 127. Ovid Technologies (Wolters Kluwer Health), 2020. https://doi.org/10.1161/res.127.suppl_1.mp133.
Liu, Xiangyu, Ali Masoudi, Alem W. Kahsai, Li-Yin Huang, Biswaranjan Pani, Dean P. Staus, Paul J. Shim, et al. “Mechanism of β2AR regulation by an intracellular positive allosteric modulator.” Science 364, no. 6447 (June 28, 2019): 1283–87. https://doi.org/10.1126/science.aaw8981.
Luttrell, Louis M., Jialu Wang, Bianca Plouffe, Jeffrey S. Smith, Lama Yamani, Suneet Kaur, Pierre-Yves Jean-Charles, et al. “Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.” Sci Signal 11, no. 549 (September 25, 2018). https://doi.org/10.1126/scisignal.aat7650.
Choi, Minjung, Dean P. Staus, Laura M. Wingler, Seungkirl Ahn, Biswaranjan Pani, William D. Capel, and Robert J. Lefkowitz. “G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor.” Sci Signal 11, no. 544 (August 21, 2018). https://doi.org/10.1126/scisignal.aar7084.