Seungkirl Ahn, PhD

Publications

Shenoy, SK, Modi, AS, Shukla, AK, Xiao, K, Berthouze, M, Ahn, S, Wilkinson, KD, Miller, WE, and Lefkowitz, RJ. "Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2." Proc Natl Acad Sci U S A 106, no. 16 (April 21, 2009): 6650-6655.

PMID
19363159
Full Text

Shukla, AK, Kim, J, Ahn, S, Xiao, K, Liedtke, W, and Lefkowitz, RJ. "[beta]-arrestin 1 mediates angiotensin II induced ubiquitination and down-regulation of TRPV4." FASEB JOURNAL 23 (April 2009).

Scholars@Duke

Ahn, S, Kim, J, Hara, MR, Ren, X-R, and Lefkowitz, RJ. "{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation." J Biol Chem 284, no. 13 (March 27, 2009): 8855-8865.

PMID
19171933
Full Text

DeWire, SM, Kim, J, Whalen, EJ, Ahn, S, Chen, M, and Lefkowitz, RJ. "Beta-arrestin-mediated signaling regulates protein synthesis." J Biol Chem 283, no. 16 (April 18, 2008): 10611-10620.

PMID
18276584
Full Text

Wisler, JW, DeWire, SM, Whalen, EJ, Violin, JD, Drake, MT, Ahn, S, Shenoy, SK, and Lefkowitz, RJ. "A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling." Proc Natl Acad Sci U S A 104, no. 42 (October 16, 2007): 16657-16662.

PMID
17925438
Full Text

Shenoy, SK, Barak, LS, Xiao, K, Ahn, S, Berthouze, M, Shukla, AK, Luttrell, LM, and Lefkowitz, RJ. "Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation." J Biol Chem 282, no. 40 (October 5, 2007): 29549-29562.

PMID
17666399
Full Text

DeWire, SM, Ahn, S, Lefkowitz, RJ, and Shenoy, SK. "Beta-arrestins and cell signaling." Annu Rev Physiol 69 (2007): 483-510. (Review)

PMID
17305471
Full Text

DeWire, SM, Ahn, S, Lefkowitz, RJ, and Shenoy, SK. "β-Arrestins and cell signaling." Annual Review of Physiology 69 (2007): 483-510.

Full Text

Gesty-Palmer, D, Chen, M, Reiter, E, Ahn, S, Nelson, CD, Wang, S, Eckhardt, AE, Cowan, CL, Spurney, RF, Luttrell, LM, and Lefkowitz, RJ. "Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation." J Biol Chem 281, no. 16 (April 21, 2006): 10856-10864.

PMID
16492667
Full Text

Ren, X-R, Reiter, E, Ahn, S, Kim, J, Chen, W, and Lefkowitz, RJ. "Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor." Proc Natl Acad Sci U S A 102, no. 5 (February 1, 2005): 1448-1453.

PMID
15671180
Full Text

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