Seungkirl Ahn, PhD

Publications

Shukla, AK, Kim, J, Ahn, S, Xiao, K, Shenoy, SK, Liedtke, W, and Lefkowitz, RJ. "Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4." The Journal of Biological Chemistry 285, no. 39 (September 2010): 30115-30125.

PMID
20650893
Full Text

Rajagopal, S, Kim, J, Ahn, S, Craig, S, Lam, CM, Gerard, NP, Gerard, C, and Lefkowitz, RJ. "Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7." Proceedings of the National Academy of Sciences of the United States of America 107, no. 2 (January 2010): 628-632.

PMID
20018651
Full Text

Kim, J, Ahn, S, Rajagopal, K, and Lefkowitz, RJ. "Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor." The Journal of Biological Chemistry 284, no. 18 (May 2009): 11953-11962.

PMID
19254952
Full Text

Shenoy, SK, Modi, AS, Shukla, AK, Xiao, K, Berthouze, M, Ahn, S, Wilkinson, KD, Miller, WE, and Lefkowitz, RJ. "Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2." Proc Natl Acad Sci U S A 106, no. 16 (April 21, 2009): 6650-6655.

PMID
19363159
Full Text

Shukla, AK, Kim, J, Ahn, S, Xiao, K, Liedtke, W, and Lefkowitz, RJ. "[beta]-arrestin 1 mediates angiotensin II induced ubiquitination and down-regulation of TRPV4." FASEB JOURNAL 23 (April 2009).

Scholars@Duke

Ahn, S, Kim, J, Hara, MR, Ren, X-R, and Lefkowitz, RJ. "{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation." The Journal of Biological Chemistry 284, no. 13 (March 2009): 8855-8865.

PMID
19171933
Full Text

DeWire, SM, Kim, J, Whalen, EJ, Ahn, S, Chen, M, and Lefkowitz, RJ. "Beta-arrestin-mediated signaling regulates protein synthesis." The Journal of Biological Chemistry 283, no. 16 (April 2008): 10611-10620.

PMID
18276584
Full Text

Wisler, JW, DeWire, SM, Whalen, EJ, Violin, JD, Drake, MT, Ahn, S, Shenoy, SK, and Lefkowitz, RJ. "A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling." Proceedings of the National Academy of Sciences of the United States of America 104, no. 42 (October 9, 2007): 16657-16662.

PMID
17925438
Full Text

Shenoy, SK, Barak, LS, Xiao, K, Ahn, S, Berthouze, M, Shukla, AK, Luttrell, LM, and Lefkowitz, RJ. "Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation." The Journal of Biological Chemistry 282, no. 40 (October 2007): 29549-29562.

PMID
17666399
Full Text

DeWire, SM, Ahn, S, Lefkowitz, RJ, and Shenoy, SK. "β-Arrestins and Cell Signaling." Annual Review of Physiology 69, no. 1 (March 2007): 483-510.

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