Seungkirl Ahn, PhD

Publications

Wei, Huijun, Seungkirl Ahn, William G. Barnes, and Robert J. Lefkowitz. “Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2.” J Biol Chem 279, no. 46 (November 12, 2004): 48255–61. https://doi.org/10.1074/jbc.M406205200.

PMID
15355986
Full Text

Ahn, Seungkirl, Sudha K. Shenoy, Huijun Wei, and Robert J. Lefkowitz. “Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor.” J Biol Chem 279, no. 34 (August 20, 2004): 35518–25. https://doi.org/10.1074/jbc.M405878200.

PMID
15205453
Full Text

Ahn, Seungkirl, Huijun Wei, Tiffany Runyan Garrison, and Robert J. Lefkowitz. “Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2.” J Biol Chem 279, no. 9 (February 27, 2004): 7807–11. https://doi.org/10.1074/jbc.C300443200.

PMID
14711824
Full Text

Wei, Huijun, Seungkirl Ahn, Sudha K. Shenoy, Sadashiva S. Karnik, László Hunyady, Louis M. Luttrell, and Robert J. Lefkowitz. “Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.” Proc Natl Acad Sci U S A 100, no. 19 (September 16, 2003): 10782–87. https://doi.org/10.1073/pnas.1834556100.

PMID
12949261
Full Text

Chen, Wei, Derk ten Berge, Jeff Brown, Seungkirl Ahn, Liaoyuan A. Hu, William E. Miller, Marc G. Caron, Larry S. Barak, Roel Nusse, and Robert J. Lefkowitz. “Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4.” Science 301, no. 5638 (September 5, 2003): 1391–94. https://doi.org/10.1126/science.1082808.

PMID
12958364
Full Text

Kim, Jihee, Seungkirl Ahn, Rishu Guo, and Yehia Daaka. “Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors.” Biochemistry 42, no. 10 (March 18, 2003): 2887–94. https://doi.org/10.1021/bi026942t.

PMID
12627954
Full Text

Ahn, Seungkirl, Christopher D. Nelson, Tiffany Runyan Garrison, William E. Miller, and Robert J. Lefkowitz. “Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference.” Proc Natl Acad Sci U S A 100, no. 4 (February 18, 2003): 1740–44. https://doi.org/10.1073/pnas.262789099.

PMID
12582207
Full Text

Ahn, Seungkirl, Jihee Kim, Carmen L. Lucaveche, Mary C. Reedy, Louis M. Luttrell, Robert J. Lefkowitz, and Yehia Daaka. “Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor.” J Biol Chem 277, no. 29 (July 19, 2002): 26642–51. https://doi.org/10.1074/jbc.M201499200.

PMID
12011079
Full Text

Pierce, K. L., A. Tohgo, S. Ahn, M. E. Field, L. M. Luttrell, and R. J. Lefkowitz. “Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding.” J Biol Chem 276, no. 25 (June 22, 2001): 23155–60. https://doi.org/10.1074/jbc.M101303200.

PMID
11290747
Full Text

Miller, W. E., S. Maudsley, S. Ahn, K. D. Khan, L. M. Luttrell, and R. J. Lefkowitz. “beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis.” J Biol Chem 275, no. 15 (April 14, 2000): 11312–19. https://doi.org/10.1074/jbc.275.15.11312.

PMID
10753943
Full Text

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