Shiao-Wen David Hsu, MD

Assistant Professor of Medicine
William Dalton Family Assistant Professor of Medical Oncology, in the School of Medicine
Member of the Duke Cancer Institute
Campus mail Dept Of Medicine, Box 3233, Durham, NC 27710
Phone (919) 681-3480
Email address shiaowen.hsu@duke.edu

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 2004 - 2007
  • Medical Resident, Medicine, University of Texas at Dallas, 2001 - 2004
  • M.D., University of North Carolina at Chapel Hill, 2001

Publications

Bu, P, Chen, K-Y, Xiang, K, Johnson, C, Crown, SB, Rakhilin, N, Ai, Y, Wang, L, Xi, R, Astapova, I, Han, Y, Li, J, Barth, BB, Lu, M, Gao, Z, Mines, R, Zhang, L, Herman, M, Hsu, D, Zhang, G-F, and Shen, X. "Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis." Cell metabolism 27, no. 6 (June 2018): 1249-1262.e4.

PMID
29706565
Full Text

Lu, M, Zessin, AS, Glover, W, and Hsu, DS. "Activation of the mTOR Pathway by Oxaliplatin in the Treatment of Colorectal Cancer Liver Metastasis." Plos One 12, no. 1 (January 6, 2017): e0169439-null.

PMID
28060954
Full Text

Zhang, T, Boominathan, R, Foulk, B, Rao, C, Kemeny, G, Strickler, JH, Abbruzzese, JL, Harrison, MR, Hsu, DS, Healy, P, Li, J, Pi, C, Prendergast, KM, Hobbs, C, Gemberling, S, George, DJ, Hurwitz, HI, Connelly, M, Garcia-Blanco, MA, and Armstrong, AJ. "Development of a Novel c-MET-Based CTC Detection Platform." Mol Cancer Res 14, no. 6 (June 2016): 539-547.

PMID
26951228
Full Text

Mi, J, Ray, P, Liu, J, Kuan, C-T, Xu, J, Hsu, D, Sullenger, BA, White, RR, and Clary, BM. "In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9." Molecular Therapy. Nucleic Acids 5 (April 26, 2016): e315-.

PMID
27115840
Full Text

Tang, X, Wu, J, Ding, C-K, Lu, M, Keenan, MM, Lin, C-C, Lin, C-A, Wang, CC, George, D, Hsu, DS, and Chi, J-T. "Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas." Cancer Research 76, no. 7 (April 2016): 1892-1903.

PMID
26833124
Full Text

Bu, P, Wang, L, Chen, K-Y, Rakhilin, N, Sun, J, Closa, A, Tung, K-L, King, S, Kristine Varanko, A, Xu, Y, Huan Chen, J, Zessin, AS, Shealy, J, Cummings, B, Hsu, D, Lipkin, SM, Moreno, V, Gümüş, ZH, and Shen, X. "miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β." Nature communications 6 (April 15, 2015): 6879-.

PMID
25872451
Full Text

Zhang, T, Boswell, EL, McCall, SJ, and Hsu, DS. "Mismatch repair gone awry: Management of Lynch syndrome." Critical reviews in oncology/hematology 93, no. 3 (March 2015): 170-179. (Review)

PMID
25459670
Full Text

Ganapathi, AM, Speicher, PJ, Englum, BR, Castleberry, AW, Migaly, J, Hsu, DS, and Mantyh, CR. "Adjuvant chemotherapy for t1 node-positive colon cancers provides significant survival benefit." Diseases of the colon and rectum 57, no. 12 (December 2014): 1341-1348.

PMID
25379998
Full Text

Zhang, J, Jima, D, Moffitt, AB, Liu, Q, Czader, M, Hsi, ED, Fedoriw, Y, Dunphy, CH, Richards, KL, Gill, JI, Sun, Z, Love, C, Scotland, P, Lock, E, Levy, S, Hsu, DS, Dunson, D, and Dave, SS. "The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells." Blood 123, no. 19 (May 2014): 2988-2996.

PMID
24682267
Full Text

Strickler, JH, McCall, S, Nixon, AB, Brady, JC, Pang, H, Rushing, C, Cohn, A, Starodub, A, Arrowood, C, Haley, S, Meadows, KL, Morse, MA, Uronis, HE, Blobe, GC, Hsu, SD, Zafar, SY, and Hurwitz, HI. "Phase i study of dasatinib in combination with capecitabine, oxaliplatin and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer." Investigational New Drugs 32, no. 2 (January 1, 2014): 330-339.

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