Steven Patierno, PhD

Professor of Medicine
Professor of Pharmacology and Cancer Biology
Professor in Family Medicine and Community Health
Core Faculty Member, Duke-Margolis Center for Health Policy
Member of the Duke Cancer Institute
Campus mail 10 Bryan Searle Drive, Seeley Mudd Building, Suite 413, Durham, NC 27710
Phone (919) 613-5093
Email address steven.patierno@duke.edu

Patierno's current translational research interests are focused on the genomics molecular biology of cancer disparities, cancer biology, molecular pharmacology and targeted experimental therapeutics to control prostate, breast and lung tumor aggressiveness. He is an internationally recognized expert in cancer control, cancer causation and molecular carcinogenesis, which includes a broad spectrum of laboratory and population level research.   Patierno is also actively engaged in cancer health disparities and healthcare delivery research focused on patient navigation, survivorship, community-based interventions, mHealth, implementation sciences, cancer care economics, and policy.

Education and Training

  • Postdoctoral Training, Norris Comprehensive Cancer, University of Southern California, 1986 - 1988
  • Ph.D., University of Texas Medical School, Houston, 1985
  • B.S., University of Connecticut, 1981

Publications

Shuin, T., P. C. Billings, J. R. Lillehaug, S. R. Patierno, P. Roy-Burman, and J. R. Landolph. “Enhanced expression of c-myc and decreased expression of c-fos protooncogenes in chemically and radiation-transformed C3H/10T1/2 Cl 8 mouse embryo cell lines.” Cancer Research 46, no. 10 (1986): 5302–11.

Scholars@Duke

Patierno, S. R., M. Sugiyama, J. P. Basilion, and M. Costa. “Preferential DNA-protein cross-linking by NiCl2 in magnesium-insoluble regions of fractionated Chinese hamster ovary cell chromatin.” Cancer Res 45, no. 11 Pt 2 (November 1985): 5787–94.

PMID
4053050
Scholars@Duke

Patierno, S. R., and M. Costa. “DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells.” Chem Biol Interact 55, no. 1–2 (October 1985): 75–91. https://doi.org/10.1016/s0009-2797(85)80121-6.

PMID
4064195
Full Text

Patierno, S. R., K. Conway, and M. Costa. “Analysis of DNA-protein crosslinking by carcinogenic nickel compounds.” Proceedings of the American Association for Cancer Research VOL. 26 (January 1, 1985).

Scholars@Duke

Pellis, N. R., S. Johnson, S. R. Patierno, and M. Costa. “Immunobiology of tumors induced with beta nickel sulfide (B-NiS).” Proceedings of the American Association for Cancer Research VOL. 26 (January 1, 1985).

Scholars@Duke

Patierno, S. R., M. DeMars, and M. Costa. “Crosslinking of specific tightly bound nuclear proteins (TbNP) to DNA of intact cells treated with carcinogenic nickel compounds.” Federation Proceedings 43, no. 7 (January 1, 1984).

Scholars@Duke

Evans, R. M., S. R. Patierno, D. S. Wang, O. Cantoni, and M. Costa. “Growth inhibition and metallothionein induction in cadmium-resistant cells by essential and non-essential metals.” Mol Pharmacol 24, no. 1 (July 1983): 77–83.

PMID
6865929
Scholars@Duke

Patierno, S. R., N. R. Pellis, R. M. Evans, and M. Costa. “Application of a modified 203Hg binding assay for metallothionein.” Life Sci 32, no. 14 (April 4, 1983): 1629–36. https://doi.org/10.1016/0024-3205(83)90870-6.

PMID
6835007
Full Text

Patierno, S. R., M. Costa, V. M. Lewis, and D. L. Peavy. “Inhibition of LPS toxicity for macrophages by metallothionein-inducing agents.” J Immunol 130, no. 4 (April 1983): 1924–29.

PMID
6187825
Scholars@Duke

Pages