Steven Patierno, PhD

Professor of Medicine
Professor of Pharmacology and Cancer Biology
Professor in Family Medicine and Community Health
Core Faculty Member, Duke-Margolis Center for Health Policy
Member of the Duke Cancer Institute
Campus mail 10 Bryan Searle Drive, Seeley Mudd Building, Suite 413, Durham, NC 27710
Phone (919) 613-5093
Email address steven.patierno@duke.edu

Patierno's current translational research interests are focused on the genomics molecular biology of cancer disparities, cancer biology, molecular pharmacology and targeted experimental therapeutics to control prostate, breast and lung tumor aggressiveness. He is an internationally recognized expert in cancer control, cancer causation and molecular carcinogenesis, which includes a broad spectrum of laboratory and population level research.   Patierno is also actively engaged in cancer health disparities and healthcare delivery research focused on patient navigation, survivorship, community-based interventions, mHealth, implementation sciences, cancer care economics, and policy.

Education and Training

  • Postdoctoral Training, Norris Comprehensive Cancer, University of Southern California, 1986 - 1988
  • Ph.D., University of Texas Medical School, Houston, 1985
  • B.S., University of Connecticut, 1981

Publications

Sauer, Scott J., Michael Tarpley, Imran Shah, Akshay V. Save, H Kim Lyerly, Steven R. Patierno, Kevin P. Williams, and Gayathri R. Devi. “Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells.” Carcinogenesis 38, no. 3 (March 1, 2017): 252–60. https://doi.org/10.1093/carcin/bgx003.

PMID
28426875
Full Text

Freedman, Jennifer, Yanru Wang, Hongliang Liu, Patricia Moorman, Terry Hyslop, Daniel George, Norman Lee, Qingyi Wei, and Steven Patierno. “Abstract B58: Single-nucleotide polymorphisms of race-related alternatively spliced genes associate with prostate cancer risk, aggressiveness and/or survival.” In Epidemiology, Lifestyle, and Genetics. American Association for Cancer Research, 2017. https://doi.org/10.1158/1538-7755.disp16-b58.

Full Text

Whitley, Elizabeth M., Peter C. Raich, Donald J. Dudley, Karen M. Freund, Electra D. Paskett, Steven R. Patierno, Melissa Simon, Victoria Warren-Mears, Frederick R. Snyder, and Frederick R. Patient Navigation Research Program Investigators. “Relation of comorbidities and patient navigation with the time to diagnostic resolution after abnormal cancer screening.” Cancer 123, no. 2 (January 1, 2017): 312–18. https://doi.org/10.1002/cncr.30316.

PMID
27648520
Full Text

Barrett, N. J., T. Vann, J. Wilder, K. ingraham, V. Worthy, X. Boyce, R. Reyes, et al. “Implementing a Health Equity Agenda at the Duke Cancer Institute.” Oncology Issues September-October 2016 (September 1, 2016): 48–57.

Scholars@Duke

Ware, Kathryn E., Jason A. Somarelli, Daneen Schaeffer, Jing Li, Tian Zhang, Sally Park, Steven R. Patierno, et al. “Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer.” Oncotarget 7, no. 31 (August 2, 2016): 50507–21. https://doi.org/10.18632/oncotarget.10476.

PMID
27409172
Full Text

Freedman, Jennifer A., Timothy J. Robinson, Bonnie LaCroix, Brendon M. Patierno, Daniel J. George, Bruce A. Sullenger, and Steven R. Patierno. “Abstract B18: Development of novel therapeutic splice-switching oligonucleotides against aggressive prostate cancer in men of African descent.” In Cell, Molecular, and Tumor Biology. American Association for Cancer Research, 2016. https://doi.org/10.1158/1538-7755.disp15-b18.

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Paskett, Electra D., Donald Dudley, Gregory S. Young, Brittany M. Bernardo, Kristen J. Wells, Elizabeth A. Calhoun, Kevin Fiscella, et al. “Impact of Patient Navigation Interventions on Timely Diagnostic Follow Up for Abnormal Cervical Screening.” J Womens Health (Larchmt) 25, no. 1 (January 2016): 15–21. https://doi.org/10.1089/jwh.2014.5094.

PMID
26625131
Full Text

Rodday, Angie Mae, Susan K. Parsons, Frederick Snyder, Melissa A. Simon, Adana A. M. Llanos, Victoria Warren-Mears, Donald Dudley, et al. “Impact of patient navigation in eliminating economic disparities in cancer care.” Cancer 121, no. 22 (November 15, 2015): 4025–34. https://doi.org/10.1002/cncr.29612.

PMID
26348120
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Ramachandran, Ambili, Frederick R. Snyder, Mira L. Katz, Julie S. Darnell, Donald J. Dudley, Steven R. Patierno, Mechelle R. Sanders, et al. “Barriers to health care contribute to delays in follow-up among women with abnormal cancer screening: Data from the Patient Navigation Research Program.” Cancer 121, no. 22 (November 15, 2015): 4016–24. https://doi.org/10.1002/cncr.29607.

PMID
26385420
Full Text

Wang, Bi-Dar, Kristin Ceniccola, Qi Yang, Ramez Andrawis, Vyomesh Patel, Youngmi Ji, Johng Rhim, et al. “Identification and Functional Validation of Reciprocal microRNA-mRNA Pairings in African American Prostate Cancer Disparities.” Clin Cancer Res 21, no. 21 (November 1, 2015): 4970–84. https://doi.org/10.1158/1078-0432.CCR-14-1566.

PMID
26089375
Full Text

Pages