Steven Sok Choi, MBBS

Associate Professor of Medicine
Campus mail Durham VA Medical Center, 508 Fulton Street, 111e, Gi Clinic, Durham, NC 27705
Phone (919) 286-6945

Hepatic stellate cell biology; Hepatic Fibrogenesis; Liver regeneration

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 2004 - 2007
  • Medical Resident, Medicine, Duke University, 2001 - 2004
  • M.B.B.S., Flinders University, 1999

Publications

Patel, YA, Gifford, E, Glass, LM, McNeil, R, Turner, MJ, Han, B, Provenzale, DT, Choi, SS, Moylan, CA, and Hunt, CM. "Diet/exercise programs are used by only one in five severely obese patients with biopsy-defined Nonalcoholic Fatty Liver Disease (NAFLD) advanced fibrosis in the Veterans Health Administration (VHA)." October 2017.

Scholars@Duke

Chan, AW, Patel, YA, and Choi, S. "Aging of the Liver: What This Means for Patients with HIV." Current HIV/AIDS reports 13, no. 6 (December 2016): 309-317. (Review)

PMID
27557619
Full Text

Chan, AW, Bryan, WE, Hashem, MA, Townsend, ML, Wang, LA, Choi, SS, and Naggie, S. "Hepatitis C (HCV) Virologic Outcomes in Veterans taking Ledipasvir/Sofosbuvir with Concomitant Acid Suppressing Medication." October 2016.

Scholars@Duke

Michelotti, GA, Tucker, A, Swiderska-Syn, M, Machado, MV, Choi, SS, Kruger, L, Soderblom, E, Thompson, JW, Mayer-Salman, M, Himburg, HA, Moylan, CA, Guy, CD, Garman, KS, Premont, RT, Chute, JP, and Diehl, AM. "Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches." Gut 65, no. 4 (April 2016): 683-692.

PMID
25596181
Full Text

Michelotti, GA, Tucker, A, Swiderska-Syn, M, Machado, MV, Choi, SS, Kruger, L, Soderblom, E, Thompson, JW, Mayer-Salman, M, Himburg, HA, Moylan, CA, Guy, CD, Garman, KS, Premont, RT, Chute, JP, and Diehl, AM. "Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches." GUT 65, no. 4 (April 2016): 683-692.

Full Text

Coombes, JD, Choi, SS, Swiderska-Syn, M, Manka, P, Reid, DT, Palma, E, Briones-Orta, MA, Xie, G, Younis, R, Kitamura, N, Della Peruta, M, Bitencourt, S, Dollé, L, Oo, YH, Mi, Z, Kuo, PC, Williams, R, Chokshi, S, Canbay, A, Claridge, LC, Eksteen, B, Diehl, AM, and Syn, W-K. "Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis." Biochimica et biophysica acta 1862, no. 1 (January 2016): 135-144.

PMID
26529285
Full Text

Pereira, TA, Syn, W-K, Machado, MV, Vidigal, PV, Resende, V, Voieta, I, Xie, G, Otoni, A, Souza, MM, Santos, ET, Chan, IS, Trindade, GVM, Choi, SS, Witek, RP, Pereira, FE, Secor, WE, Andrade, ZA, Lambertucci, JR, and Diehl, AM. "Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni." Clinical science (London, England : 1979) 129, no. 10 (November 2015): 875-883.

PMID
26201095
Full Text

Rabatin, A, Hashem, M, Townsend, ML, Bryan, WE, Moylan, CA, Choi, SS, and Naggie, S. "Treatment Outcomes of Veterans with Decompensated Cirrhosis Receiving All Oral Direct Acting Antiviral Hepatitis C Therapy." October 2015.

Scholars@Duke

Uschner, FE, Ranabhat, G, Granzow, M, Choi, SS, Klein, S, Schierwagen, R, Raskopf, E, Gautsch, S, Van der Ven, PF, Strassburg, CP, Fuerst, DO, Hiththetiya, K, Sauerbruch, T, Diehl, AM, and Trebicka, J. "Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension." October 2015.

Scholars@Duke

Uschner, FE, Ranabhat, G, Choi, SS, Granzow, M, Klein, S, Schierwagen, R, Raskopf, E, Gautsch, S, van der Ven, PFM, Fürst, DO, Strassburg, CP, Sauerbruch, T, Diehl, AM, and Trebicka, J. "Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension." Scientific reports 5 (September 28, 2015): 14573-.

PMID
26412302
Full Text

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