Stuart Dean Russell, MD

Professor of Medicine
Campus mail 0372 Hosp South, Durham, NC 27710
Phone (919) 350-2243
Email address stuart.russell@duke.edu

The focus of my research is on the care of patients with advanced heart failure.  We are involved in single and multicenter clinical trials evaluating new drug therapies for patients with advanced heart failure.  Additionally, we are working to understand the exercise limitations and how to improve them in this patient population. We are trying to understand some of the basic pathophysiologic consequences of heart failure such as the origin of the symptoms of dyspnea and fatigue.

We have established an invasive cardiopulmonary exercise lab in which we carry out the majority of our research. We have the ability to monitor hemodynamics and gas exchange during exercise. Additionally, we have been the exercise core lab for various trials involving exercise as an endpoint in the evaluation of new therapies for heart failure. 

Key words include: Advanced heart failure, Exercise physiology, and Cardiac transplantation.

Education and Training

  • Transplant Cardiology Fellowship, University of California at Los Angeles, 1997 - 1997
  • Cardiovascular Disease Fellowship, Medicine, Duke University School of Medicine, 1994 - 1997
  • Internal Medicine Residency, Johns Hopkins University School of Medicine, 1991 - 1994
  • M.D., University of Washington School of Medicine, 1991

Grants

Publications

Yalcin, Yunus C., Rahatullah Muslem, Kevin M. Veen, OsamaI Soliman, Dennis A. Hesselink, Alina A. Constantinescu, Jasper J. Brugts, et al. “Impact of continuous flow left ventricular assist device therapy on chronic kidney disease: a longitudinal multicenter study.” J Card Fail, January 22, 2020. https://doi.org/10.1016/j.cardfail.2020.01.010.

PMID
31981698
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Gilotra, N. A., B. L. Wanamaker, H. Rahim, K. Kunkel, G. Yenokyan, S. P. Schulman, R. J. Tedford, S. D. Russell, and H. A. Silber. “Usefulness of Noninvasively Measured Pulse Amplitude Changes During the Valsalva Maneuver to Identify Hospitalized Heart Failure Patients at Risk of 30-Day Heart Failure Events (from the PRESSURE-HF Study).” American Journal of Cardiology, January 1, 2020. https://doi.org/10.1016/j.amjcard.2019.12.027.

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Crawford, Todd C., Peter J. Leary, Charles D. Fraser, Alejandro Suarez-Pierre, J Trent Magruder, William A. Baumgartner, Kenton J. Zehr, et al. “Impact of the New Pulmonary Hypertension Definition on Heart Transplant Outcomes: Expanding the Hemodynamic Risk Profile.” Chest 157, no. 1 (January 2020): 151–61. https://doi.org/10.1016/j.chest.2019.07.028.

PMID
31446063
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Stehlik, Josef, Maria Mountis, Donald Haas, Maryse Palardy, Amrut V. Ambardekar, Jerry D. Estep, Gregory Ewald, et al. “Quality of life and treatment preference for ventricular assist device therapy in ambulatory advanced heart failure: A report from the REVIVAL study.” J Heart Lung Transplant 39, no. 1 (January 2020): 27–36. https://doi.org/10.1016/j.healun.2019.11.006.

PMID
31822442
Full Text

Mawardi, George, Tim M. Markman, Rahatullah Muslem, Minoosh Sobhanian, Maureen Converse, Holly B. Meadows, Walter E. Uber, et al. “SSRI/SNRI Therapy is Associated With a Higher Risk of Gastrointestinal Bleeding in LVAD Patients.” Heart Lung Circ, August 8, 2019. https://doi.org/10.1016/j.hlc.2019.07.011.

PMID
31635997
Full Text

Mounsey, Louisa A., Patricia P. Chang, Carla A. Sueta, Kunihiro Matsushita, Stuart D. Russell, and Melissa C. Caughey. “In-Hospital and Postdischarge Mortality Among Patients With Acute Decompensated Heart Failure Hospitalizations Ending on the Weekend Versus Weekday: The ARIC Study Community Surveillance.” J Am Heart Assoc 8, no. 15 (August 6, 2019): e011631. https://doi.org/10.1161/JAHA.118.011631.

PMID
31319746
Full Text

Lewis, Gavin A., Erik B. Schelbert, Josephine H. Naish, Emma Bedson, Susanna Dodd, Helen Eccleson, Dannii Clayton, et al. “Pirfenidone in Heart Failure with Preserved Ejection Fraction-Rationale and Design of the PIROUETTE Trial.” Cardiovasc Drugs Ther 33, no. 4 (August 2019): 461–70. https://doi.org/10.1007/s10557-019-06876-y.

PMID
31069575
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James, Theodore W., Jessica E. S. Shay, David Furfaro, Burak Ozseker, Stuart D. Russell, Aliaksei Pustavoitau, Nicole Rizkalla, et al. “Cardiac Events Within the 30-Day Postoperative Period Is Associated With Increased 1-Year Mortality Among Deceased-Donor Liver Transplant Recipients.” Exp Clin Transplant 17, no. 3 (June 2019): 370–74. https://doi.org/10.6002/ect.2017.0276.

PMID
30084756
Full Text

Fudim, M Marat, R. L. Boortz-Marx, A. Ganesh, A. D. Devore, C. Patel, J. G. Rogers, A. Coburn, et al. “Splanchnic nerve blockade in chronic heart failure (Splanchnic HF-2).” In European Journal of Heart Failure, 21:168–69. WILEY, 2019.

Scholars@Duke

Truby, L. K., R. Agarwal, S. D. Russell, C. B. Patel, and J. G. Rogers. “The Role of Transpulmonary Gradient and Mean Pulmonary Artery Pressure in Risk Stratification of Heart Transplant Candidates with Pulmonary Hypertension.” In The Journal of Heart and Lung Transplantation, 38:S285–86. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.715.

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