Sudarshan Rajagopal, MD, PhD

Assistant Professor of Medicine
Assistant Professor in Biochemistry
Campus mail 3126, Durham, NC 27710
Phone (919) 684-6237
Email address sudarshan.rajagopal@duke.edu
In Their Words

Education and Training

  • Clinical Fellowship, Cardiovascular Disease, Duke University School of Medicine, 2011 - 2013
  • Research Fellowship, Duke University School of Medicine, 2008 - 2011
  • Resident, Internal Medicine, Duke University School of Medicine, 2006 - 2008
  • M.D., University of Chicago, 2006
  • Ph.D., University of Chicago, 2004

Publications

Rajagopal, S, and Kent, SBH. "Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit." Protein science : a publication of the Protein Society 16, no. 9 (September 2007): 2056-2064.

PMID
17660260
Full Text

Ihee, H, Rajagopal, S, Srajer, V, Pahl, R, Anderson, S, Schmidt, M, Schotte, F, Anfinrud, PA, Wulff, M, and Moffat, K. "Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds." Proceedings of the National Academy of Sciences of the United States of America 102, no. 20 (May 3, 2005): 7145-7150.

PMID
15870207
Full Text

Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, and Moffat, K. "A structural pathway for signaling in the E46Q mutant of photoactive yellow protein." Structure (London, England : 1993) 13, no. 1 (January 2005): 55-63.

PMID
15642261
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Rajagopal, S, Key, JM, Purcell, EB, Boerema, DJ, and Moffat, K. "Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli." Photochemistry and photobiology 80, no. 3 (November 2004): 542-547.

PMID
15453820
Full Text

Rajagopal, S, Kostov, KS, and Moffat, K. "Analytical trapping: extraction of time-independent structures from time-dependent crystallographic data." Journal of structural biology 147, no. 3 (September 2004): 211-222.

PMID
15450291
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Anderson, S, Srajer, V, Pahl, R, Rajagopal, S, Schotte, F, Anfinrud, P, Wulff, M, and Moffat, K. "Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein." Structure (London, England : 1993) 12, no. 6 (June 2004): 1039-1045.

PMID
15274923
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Rajagopal, S, Schmidt, M, Anderson, S, Ihee, H, and Moffat, K. "Analysis of experimental time-resolved crystallographic data by singular value decomposition." Acta crystallographica. Section D, Biological crystallography 60, no. Pt 5 (May 2004): 860-871.

PMID
15103131
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Schmidt, M, Pahl, R, Srajer, V, Anderson, S, Ren, Z, Ihee, H, Rajagopal, S, and Moffat, K. "Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data." Proceedings of the National Academy of Sciences of the United States of America 101, no. 14 (April 2004): 4799-4804.

PMID
15041745
Full Text

Rajagopal, S, Key, JM, Purcell, EB, Boerema, DJ, and Moffat, K. "Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli." Photochemistry and Photobiology 80, no. 3 (January 1, 2004): 542-547.

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Rajagopal, S, and Moffat, K. "Erratum: Crystal structure of a photoactive yellow protein from a sensor histidine kinase: Conformational variability and signal transduction (Proceedings of the National Academy of Sciences of the United States of America (February 18, 2003) 100:4 (1649-1654)." Proceedings of the National Academy of Sciences of the United States of America 100, no. 13 (June 24, 2003): 8037-.

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