Sudha Kaup Shenoy, PhD

Associate Professor in Medicine

Associate Professor in Cell Biology

Member of the Duke Cancer Institute

Campus mail 148-A CARL Bldg, Durham, NC 27710

Phone (919) 681-5061

Email address skshenoy@dm.duke.edu

Education and Training

Ph.D., Oklahoma State University at Stillwater, 1998

Grants

Publications

Toth, Krisztian, Karim Nagi, Lauren M. Slosky, Lauren Rochelle, Caroline Ray, Suneet Kaur, Sudha K. Shenoy, Marc G. Caron, and Larry S. Barak. “Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs.” Acs Pharmacol Transl Sci 2, no. 4 (August 9, 2019): 230–46. https://doi.org/10.1021/acsptsci.9b00018.

PMID

32259059

Full Text

Yu, Samuel Mon-Wei, Pierre-Yves Jean-Charles, Dennis M. Abraham, Suneet Kaur, Clarice Gareri, Lan Mao, Howard A. Rockman, and Sudha K. Shenoy. “The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling.” J Biol Chem 294, no. 7 (February 15, 2019): 2500–2518. https://doi.org/10.1074/jbc.RA118.004926.

PMID

30538132

Full Text

Nagi, Karim, and Sudha K. Shenoy. “Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET.” Methods Mol Biol 1957 (2019): 93–104. https://doi.org/10.1007/978-1-4939-9158-7_6.

PMID

30919349

Full Text

Zhang, Lisheng, Jiao-Hui Wu, Tai-Qin Huang, Igor Nepliouev, Leigh Brian, Zhushan Zhang, Virginia Wertman, et al. “Drebrin regulates angiotensin II-induced aortic remodelling.” Cardiovasc Res 114, no. 13 (November 1, 2018): 1806–15. https://doi.org/10.1093/cvr/cvy151.

PMID

29931051

Full Text

Jean-Charles, Pierre-Yves, Jiao-Hui Wu, Lisheng Zhang, Suneet Kaur, Igor Nepliouev, Jonathan A. Stiber, Leigh Brian, et al. “USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis.” Arterioscler Thromb Vasc Biol 38, no. 10 (October 2018): 2295–2305. https://doi.org/10.1161/ATVBAHA.118.311071.

PMID

30354204

Full Text

Luttrell, Louis M., Jialu Wang, Bianca Plouffe, Jeffrey S. Smith, Lama Yamani, Suneet Kaur, Pierre-Yves Jean-Charles, et al. “Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.” Sci Signal 11, no. 549 (September 25, 2018). https://doi.org/10.1126/scisignal.aat7650.

PMID

30254056

Full Text

Rajagopal, Sudarshan, and Sudha K. Shenoy. “GPCR desensitization: Acute and prolonged phases.” Cell Signal 41 (January 2018): 9–16. https://doi.org/10.1016/j.cellsig.2017.01.024.

PMID

28137506

Full Text

Freedman, Neil J., and Sudha K. Shenoy. “Regulation of inflammation by β-arrestins: Not just receptor tales.” Cell Signal 41 (January 2018): 41–45. https://doi.org/10.1016/j.cellsig.2017.02.008.

PMID

28189586

Full Text

Zhang, Lisheng, Jiao-Hui Wu, James C. Otto, Susan B. Gurley, Elizabeth R. Hauser, Sudha K. Shenoy, Karim Nagi, et al. “Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells.” Cardiovasc Res 113, no. 13 (November 1, 2017): 1551–59. https://doi.org/10.1093/cvr/cvx177.

PMID

29048463

Full Text

Jean-Charles, Pierre-Yves, Samuel Mon-Wei Yu, Dennis Abraham, Reddy Peera Kommaddi, Lan Mao, Ryan T. Strachan, Zhu-Shan Zhang, et al. “Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.” Jci Insight 2, no. 17 (September 7, 2017). https://doi.org/10.1172/jci.insight.95998.

PMID

28878120

Full Text

Sudha Kaup Shenoy, PhD

Education and Training

Grants

Publications

Pages