Sudha Kaup Shenoy, PhD

Associate Professor in Medicine
Associate Professor in Cell Biology
Member of the Duke Cancer Institute
Campus mail 412 Sands Bldg, Durham, NC 27710
Phone (919) 681-5061
Email address skshenoy@dm.duke.edu

Education and Training

  • Ph.D., Oklahoma State University at Stillwater, 1998

Publications

Yu, SM-W, Jean-Charles, P-Y, Abraham, DM, Kaur, S, Gareri, C, Mao, L, Rockman, HA, and Shenoy, SK. "The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling." The Journal of Biological Chemistry 294, no. 7 (February 2019): 2500-2518.

PMID
30538132
Full Text

Nagi, K, and Shenoy, SK. "Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET." Methods in Molecular Biology (Clifton, N.J.) 1957 (January 2019): 93-104.

PMID
30919349
Full Text

Zhang, L, Wu, J-H, Huang, T-Q, Nepliouev, I, Brian, L, Zhang, Z, Wertman, V, Rudemiller, NP, McMahon, TJ, Shenoy, SK, Miller, FJ, Crowley, SD, Freedman, NJ, and Stiber, JA. "Drebrin regulates angiotensin II-induced aortic remodelling." Cardiovascular Research 114, no. 13 (November 2018): 1806-1815.

PMID
29931051
Full Text

Jean-Charles, P-Y, Wu, J-H, Zhang, L, Kaur, S, Nepliouev, I, Stiber, JA, Brian, L, Qi, R, Wertman, V, Shenoy, SK, and Freedman, NJ. "USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis." Arteriosclerosis, Thrombosis, and Vascular Biology 38, no. 10 (October 2018): 2295-2305.

PMID
30354204
Full Text

Luttrell, LM, Wang, J, Plouffe, B, Smith, JS, Yamani, L, Kaur, S, Jean-Charles, P-Y, Gauthier, C, Lee, M-H, Pani, B, Kim, J, Ahn, S, Rajagopal, S, Reiter, E, Bouvier, M, Shenoy, SK, Laporte, SA, Rockman, HA, and Lefkowitz, RJ. "Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9." Science Signaling 11, no. 549 (September 25, 2018).

PMID
30254056
Full Text

Rajagopal, S, and Shenoy, SK. "GPCR desensitization: Acute and prolonged phases." Cellular Signalling 41 (January 2018): 9-16. (Review)

PMID
28137506
Full Text

Freedman, NJ, and Shenoy, SK. "Regulation of inflammation by β-arrestins: Not just receptor tales." Cellular Signalling 41 (January 2018): 41-45. (Review)

PMID
28189586
Full Text

Zhang, L, Wu, J-H, Otto, JC, Gurley, SB, Hauser, ER, Shenoy, SK, Nagi, K, Brian, L, Wertman, V, Mattocks, N, Lawson, JH, and Freedman, NJ. "Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells." Cardiovascular Research 113, no. 13 (November 2017): 1551-1559.

PMID
29048463
Full Text

Jean-Charles, P-Y, Yu, SM-W, Abraham, D, Kommaddi, RP, Mao, L, Strachan, RT, Zhang, Z-S, Bowles, DE, Brian, L, Stiber, JA, Jones, SN, Koch, WJ, Rockman, HA, and Shenoy, SK. "Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling." JCI insight 2, no. 17 (September 7, 2017).

PMID
28878120
Full Text

Jean-Charles, P-Y, Kaur, S, and Shenoy, SK. "G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms." Journal of Cardiovascular Pharmacology 70, no. 3 (September 2017): 142-158. (Review)

PMID
28328745
Full Text

Pages