Cardiology

Sudha Kaup Shenoy, PhD

Associate Professor in Medicine
Associate Professor in Cell Biology
Member of the Duke Cancer Institute
Campus mail 412 Sands Bldg, Durham, NC 27710
Phone (919) 681-5061
Email address skshenoy@dm.duke.edu

Education and Training

  • Ph.D., Oklahoma State University at Stillwater, 1998

Grants

Publications

Yu, SM-W, Jean-Charles, P-Y, Abraham, DM, Kaur, S, Gareri, C, Mao, L, Rockman, HA, and Shenoy, SK. "The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling." The Journal of Biological Chemistry 294, no. 7 (February 2019): 2500-2518.

PMID
30538132
Full Text

Nagi, K, and Shenoy, SK. "Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET." Methods in Molecular Biology (Clifton, N.J.) 1957 (January 2019): 93-104.

PMID
30919349
Full Text

Zhang, L, Wu, J-H, Huang, T-Q, Nepliouev, I, Brian, L, Zhang, Z, Wertman, V, Rudemiller, NP, McMahon, TJ, Shenoy, SK, Miller, FJ, Crowley, SD, Freedman, NJ, and Stiber, JA. "Drebrin regulates angiotensin II-induced aortic remodelling." Cardiovascular Research 114, no. 13 (November 2018): 1806-1815.

PMID
29931051
Full Text

Jean-Charles, P-Y, Wu, J-H, Zhang, L, Kaur, S, Nepliouev, I, Stiber, JA, Brian, L, Qi, R, Wertman, V, Shenoy, SK, and Freedman, NJ. "USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis." Arteriosclerosis, Thrombosis, and Vascular Biology 38, no. 10 (October 2018): 2295-2305.

PMID
30354204
Full Text

Luttrell, LM, Wang, J, Plouffe, B, Smith, JS, Yamani, L, Kaur, S, Jean-Charles, P-Y, Gauthier, C, Lee, M-H, Pani, B, Kim, J, Ahn, S, Rajagopal, S, Reiter, E, Bouvier, M, Shenoy, SK, Laporte, SA, Rockman, HA, and Lefkowitz, RJ. "Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9." Science Signaling 11, no. 549 (September 25, 2018).

PMID
30254056
Full Text

Rajagopal, S, and Shenoy, SK. "GPCR desensitization: Acute and prolonged phases." Cellular Signalling 41 (January 2018): 9-16. (Review)

PMID
28137506
Full Text

Freedman, NJ, and Shenoy, SK. "Regulation of inflammation by β-arrestins: Not just receptor tales." Cellular Signalling 41 (January 2018): 41-45. (Review)

PMID
28189586
Full Text

Zhang, L, Wu, J-H, Otto, JC, Gurley, SB, Hauser, ER, Shenoy, SK, Nagi, K, Brian, L, Wertman, V, Mattocks, N, Lawson, JH, and Freedman, NJ. "Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells." Cardiovascular Research 113, no. 13 (November 2017): 1551-1559.

PMID
29048463
Full Text

Jean-Charles, P-Y, Yu, SM-W, Abraham, D, Kommaddi, RP, Mao, L, Strachan, RT, Zhang, Z-S, Bowles, DE, Brian, L, Stiber, JA, Jones, SN, Koch, WJ, Rockman, HA, and Shenoy, SK. "Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling." JCI insight 2, no. 17 (September 7, 2017).

PMID
28878120
Full Text

Jean-Charles, P-Y, Kaur, S, and Shenoy, SK. "G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms." Journal of Cardiovascular Pharmacology 70, no. 3 (September 2017): 142-158. (Review)

PMID
28328745
Full Text

Pages