Svati Hasmukh Shah, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Member of Duke Molecular Physiology Institute
Campus mail DUMC Box 3445, Durham, NC 27710
Phone (919) 684-1808
Email address svati.shah@duke.edu
In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 2001 - 2005
  • Medical Resident, Medicine, Children's Hospital Boston, 1998 - 2001
  • M.D., University of Washington, 1998
  • M.H.S., Johns Hopkins University, 1994

Publications

Webb, TR, Erdmann, J, Stirrups, KE, Stitziel, NO, Masca, NGD, Jansen, H, Kanoni, S, Nelson, CP, Ferrario, PG, König, IR, Eicher, JD, Johnson, AD, Hamby, SE, Betsholtz, C, Ruusalepp, A, Franzén, O, Schadt, EE, Björkegren, JLM, Weeke, PE, Auer, PL, Schick, UM, Lu, Y, Zhang, H, Dube, M-P, Goel, A, Farrall, M, Peloso, GM, Won, H-H, Do, R, van Iperen, E, Kruppa, J, Mahajan, A, Scott, RA, Willenborg, C, Braund, PS, van Capelleveen, JC, Doney, ASF, Donnelly, LA, Asselta, R, Merlini, PA, Duga, S, Marziliano, N, Denny, JC, Shaffer, C, El-Mokhtari, NE, Franke, A, Heilmann, S, Hengstenberg, C, Hoffmann, P, Holmen, OL, Hveem, K, Jansson, J-H, Jöckel, K-H, Kessler, T, Kriebel, J, Laugwitz, KL, Marouli, E, Martinelli, N, McCarthy, MI, Van Zuydam, NR, Meisinger, C, Esko, T, Mihailov, E, Escher, SA, Alver, M, Moebus, S, Morris, AD, Virtamo, J, Nikpay, M, Olivieri, O, Provost, S, AlQarawi, A, Robertson, NR, Akinsansya, KO, Reilly, DF, Vogt, TF, Yin, W, Asselbergs, FW, Kooperberg, C, Jackson, RD, Stahl, E, Müller-Nurasyid, M, Strauch, K, Varga, TV, Waldenberger, M, Wellcome Trust Case Control Consortium, , Zeng, L, Chowdhury, R, Salomaa, V, Ford, I, Jukema, JW, Amouyel, P, Kontto, J, MORGAM Investigators, , Nordestgaard, BG, Ferrières, J, Saleheen, D, Sattar, N, Surendran, P, Wagner, A, Young, R, Howson, JMM, Butterworth, AS, Danesh, J, Ardissino, D, Bottinger, EP, Erbel, R, Franks, PW, Girelli, D, Hall, AS, Hovingh, GK, Kastrati, A, Lieb, W, Meitinger, T, Kraus, WE, Shah, SH, McPherson, R, Orho-Melander, M, Melander, O, Metspalu, A, Palmer, CNA, Peters, A, Rader, DJ, Reilly, MP, Loos, RJF, Reiner, AP, Roden, DM, Tardif, J-C, Thompson, JR, Wareham, NJ, Watkins, H, Willer, CJ, Samani, NJ, Schunkert, H, Deloukas, P, Kathiresan, S, and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, . "Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease." Journal of the American College of Cardiology 69, no. 7 (February 2017): 823-836.

PMID
28209224
Full Text

McGarrah, RW, Kelly, JP, Craig, DM, Haynes, C, Jessee, RC, Huffman, KM, Kraus, WE, and Shah, SH. "A Novel Protein Glycan-Derived Inflammation Biomarker Independently Predicts Cardiovascular Disease and Modifies the Association of HDL Subclasses with Mortality." Clinical Chemistry 63, no. 1 (January 2017): 288-296.

PMID
27811210
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Ward-Caviness, CK, Neas, LM, Blach, C, Haynes, CS, LaRocque-Abramson, K, Grass, E, Dowdy, ZE, Devlin, RB, Diaz-Sanchez, D, Cascio, WE, Miranda, ML, Gregory, SG, Shah, SH, Kraus, WE, and Hauser, ER. "A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic." Plos One 12, no. 3 (January 2017): e0173880-null.

PMID
28355232
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Brænne, I, Zeng, L, Willenborg, C, Tragante, V, Kessler, T, CARDIoGRAM Consortium, , CARDIoGRAMplusC4D Consortium, , Willer, CJ, Laakso, M, Wallentin, L, Franks, PW, Salomaa, V, Dehghan, A, Meitinger, T, Samani, NJ, Asselbergs, FW, Erdmann, J, and Schunkert, H. "Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk." Plos One 12, no. 8 (January 2017): e0182999-null.

PMID
28829817
Full Text

Breitner, S, Schneider, A, Devlin, RB, Ward-Caviness, CK, Diaz-Sanchez, D, Neas, LM, Cascio, WE, Peters, A, Hauser, ER, Shah, SH, and Kraus, WE. "Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac catheterization cohort." Environment International 97 (December 2016): 76-84.

PMID
27792908
Full Text

Nüesch, E, Dale, C, Palmer, TM, White, J, Keating, BJ, van Iperen, EP, Goel, A, Padmanabhan, S, Asselbergs, FW, EPIC-Netherland Investigators, , Verschuren, WM, Wijmenga, C, Van der Schouw, YT, Onland-Moret, NC, Lange, LA, Hovingh, GK, Sivapalaratnam, S, Morris, RW, Whincup, PH, Wannamethe, GS, Gaunt, TR, Ebrahim, S, Steel, L, Nair, N, Reiner, AP, Kooperberg, C, Wilson, JF, Bolton, JL, McLachlan, S, Price, JF, Strachan, MW, Robertson, CM, Kleber, ME, Delgado, G, März, W, Melander, O, Dominiczak, AF, Farrall, M, Watkins, H, Leusink, M, Maitland-van der Zee, AH, de Groot, MC, Dudbridge, F, Hingorani, A, Ben-Shlomo, Y, Lawlor, DA, UCLEB Investigators, , Amuzu, A, Caufield, M, Cavadino, A, Cooper, J, Davies, TL, IN Day, , Drenos, F, Engmann, J, Finan, C, Giambartolomei, C, Hardy, R, Humphries, SE, Hypponen, E, Kivimaki, M, Kuh, D, Kumari, M, Ong, K, Plagnol, V, Power, C, Richards, M, Shah, S, Shah, T, Sofat, R, Talmud, PJ, Wareham, N, Warren, H, Whittaker, JC, Wong, A, Zabaneh, D, Davey Smith, G, Wells, JC, Leon, DA, Holmes, MV, and Casas, JP. "Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis." International Journal of Epidemiology 45, no. 6 (December 2016): 1927-1937.

PMID
25979724
Full Text

Hampel, R, Breitner, S, Kraus, WE, Hauser, E, Shah, S, Ward-Caviness, CK, Devlin, R, Diaz-Sanchez, D, Neas, L, Cascio, W, Peters, A, and Schneider, A. "Short-term effects of air temperature on plasma metabolite concentrations in patients undergoing cardiac catheterization." Environmental Research 151 (November 2016): 224-232.

PMID
27500855
Full Text

Loley, C, Alver, M, Assimes, TL, Bjonnes, A, Goel, A, Gustafsson, S, Hernesniemi, J, Hopewell, JC, Kanoni, S, Kleber, ME, Lau, KW, Lu, Y, Lyytikäinen, L-P, Nelson, CP, Nikpay, M, Qu, L, Salfati, E, Scholz, M, Tukiainen, T, Willenborg, C, Won, H-H, Zeng, L, Zhang, W, Anand, SS, Beutner, F, Bottinger, EP, Clarke, R, Dedoussis, G, Do, R, Esko, T, Eskola, M, Farrall, M, Gauguier, D, Giedraitis, V, Granger, CB, Hall, AS, Hamsten, A, Hazen, SL, Huang, J, Kähönen, M, Kyriakou, T, Laaksonen, R, Lind, L, Lindgren, C, Magnusson, PKE, Marouli, E, Mihailov, E, Morris, AP, Nikus, K, Pedersen, N, Rallidis, L, Salomaa, V, Shah, SH, Stewart, AFR, Thompson, JR, Zalloua, PA, Chambers, JC, Collins, R, Ingelsson, E, Iribarren, C, Karhunen, PJ, Kooner, JS, Lehtimäki, T, Loos, RJF, März, W, McPherson, R, Metspalu, A, Reilly, MP, Ripatti, S, Sanghera, DK, Thiery, J, Watkins, H, Deloukas, P, Kathiresan, S, Samani, NJ, Schunkert, H, Erdmann, J, and König, IR. "No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis." Scientific Reports 6 (October 12, 2016): 35278-null.

PMID
27731410
Full Text

McGarrah, RW, and Shah, SH. "Exomes, Proteins, and Cardiovascular Disease: Making Sense of the Signals." Circulation. Cardiovascular Genetics 9, no. 4 (August 2016): 318-319.

PMID
27531916
Full Text

Hunter, WG, Kelly, JP, McGarrah, RW, Khouri, MG, Craig, D, Haynes, C, Ilkayeva, O, Stevens, RD, Bain, JR, Muehlbauer, MJ, Newgard, CB, Felker, GM, Hernandez, AF, Velazquez, EJ, Kraus, WE, and Shah, SH. "Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure." Journal of the American Heart Association 5, no. 8 (July 29, 2016).

PMID
27473038
Full Text

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