Thomas William LeBlanc, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member of the Duke Cancer Institute
Campus mail 2424 Erwin Road, Suite 602, Durham, NC 27705
Phone (919) 668-2115
Email address

Dr. LeBlanc is a medical oncologist, palliative care physician, and patient experience researcher.  His clinical practice focuses on the care of patients with hematologic malignancies, with a particular emphasis on myeloid conditions and acute leukemias including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPNs / MPDs, CML).  He is an active member of the inpatient non-transplant hematologic malignancies care team, based on the 9100 ward of Duke University Hospital.

His research interests converge on common issues faced by people with cancer, particularly those with high-risk or relapsed/refractory hematologic malignancies. Issues of symptom burden and quality of life are of central importance in these settings, and may lead patients to face difficult decision-making scenarios. Dr. LeBlanc’s research explores the experience of patients and families in these settings, and aims to improve patients experiences living with blood cancers, including the involvement of specialist palliative care services to provide an extra layer of support along with their comprehensive cancer care, to improve symptom management and quality of life.

Dr. LeBlanc is the recipient of a Junior Career Development Award grant from the National Palliative Care Research Center (NPCRC), a Sojourns Scholars Leadership Award from the Cambia Health Foundation, and a Mentored Research Scholar Grant from the American Cancer Society. These grants have funded efforts to better understand the experience of patients living with AML, including studies of symptom burden, quality of life, distress, understanding of prognosis, and treatment decision-making. This work has been mentored by a team of expert researchers, including Drs. Amy Abernethy, James Tulsky, Karen Steinhauser, Kathryn Pollak, and Peter Ubel.  Dr. LeBlanc's work in palliative care research led to his recognition as an "Inspirational Leader under 40" by the American Academy of Hospice and Palliative Medicine (AAHPM), and "fellow" status from the Academy in 2016. Dr. LeBlanc was the 2017-18 Chair of the ASCO Ethics Committee, and Chairs the Scientific Review Committee of the NIH/NINR-funded Palliative Care Research Cooperative Group (PCRC; He has served on various national guideline panels for AML, and for palliative/supportive care issues in oncology. 

He completed residency training in Internal Medicine at Duke, as well as fellowships in Medical Oncology and Hospice and Palliative Medicine.  He graduated from the Duke University School of Medicine, also earning a Master of Arts degree in Philosophy during that time, and served as Chief Medical Resident at the Durham VA Medical Center in 2010-11.  He holds board certifications in Medical Oncology, and in Hospice and Palliative Medicine.  He is actively involved with teaching of medical students and housestaff at Duke, particularly with regards to issues of patient-doctor communication, and is mentoring several Duke trainees on research projects.

Education and Training

  • Fellow, Medical Oncology, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Hospice And Palliative Medicine, Duke University School of Medicine, 2011 - 2012
  • Chief Medical Resident, Duke University School of Medicine, 2010 - 2011
  • Resident, Duke University School of Medicine, 2007 - 2009
  • Intern, Duke University School of Medicine, 2006 - 2007
  • M.D., Duke University, 2006


Sandhu, Sahil, Zoe King, Michelle Wong, Sean Bissell, Jessica Sperling, Megan Gray, William Ratliff, Kris Herring, and Thomas W. LeBlanc. “Implementation of Electronic Patient-Reported Outcomes in Routine Cancer Care at an Academic Center: Identifying Opportunities and Challenges.” Jco Oncol Pract, September 14, 2020, OP2000357.

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Sekeres, Mikkael A., Gordon Guyatt, Gregory Abel, Shabbir Alibhai, Jessica K. Altman, Rena Buckstein, Hannah Choe, et al. “American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults.” Blood Adv 4, no. 15 (August 11, 2020): 3528–49.

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Zaleta, Alexandra K., Melissa F. Miller, Julie S. Olson, Eva Y. N. Yuen, Thomas W. LeBlanc, Craig E. Cole, Shauna McManus, and Joanne S. Buzaglo. “Symptom Burden, Perceived Control, and Quality of Life Among Patients Living With Multiple Myeloma.” J Natl Compr Canc Netw 18, no. 8 (August 2020): 1087–95.

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Hildenbrand, Jordan, Cheyenne Corbett, Debra Davis, Kris Herring, Susan Locke, Jesse Troy, Steve Wolf, et al. “Digital Supportive Care Awareness and Navigation (D-SCAN): Qualitative and Quantitative Results of a Pilot Randomized Trial in Patients with Advanced Cancer.” In Journal of Pain and Symptom Management, 60:272–272, 2020.


Porter, Laura, Thomas LeBlanc, Janet Bull, and Laura Hanson. “Caregiver-Guided Pain Management for Advanced Cancer: Results of a Randomized Controlled Trial.” In Journal of Pain and Symptom Management, 60:192–93, 2020.


Shah, Anne, Allison Petrilla, Mayvis Rebeira, Joseph Feliciano, Julie Lisano, and Thomas W. LeBlanc. “Health Care Resource Utilization and Costs Among Medicare Beneficiaries Newly Diagnosed With Peripheral T-cell Lymphoma: A Retrospective Claims Analysis.” Clinical Lymphoma Myeloma and Leukemia, July 2020.

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Rao, Vinay B., Emmanuelle Belanger, Pamela C. Egan, Thomas W. LeBlanc, and Adam J. Olszewski. “Early Palliative Care Services and End-of-Life Care in Medicare Beneficiaries with Hematologic Malignancies: A Population-Based Retrospective Cohort Study.” J Palliat Med, June 29, 2020.

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