Thomas William LeBlanc, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member of the Duke Cancer Institute
Campus mail 2424 Erwin Road, Suite 602, Durham, NC 27705
Phone (919) 668-2115
Email address thomas.leblanc@duke.edu

I am a medical oncologist, palliative care physician, and patient experience researcher.  My clinical practice focuses on the care of patients with hematologic malignancies, with a particular emphasis on myeloid conditions and acute leukemias including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPNs / MPDs, CML).  

As founding Director of the Duke Cancer Patient Experience Research Program (CPEP), my research investigates common issues faced by people with cancer, including issues of symptom burden, quality of life, psychological distress, prognostic understanding, and treatment decision-making. This work aims to improve patients' experiences living with serious illnesses like blood cancers, including the integration of specialist palliative care services to provide an extra layer of support along with their comprehensive cancer care. More broadly, our team in CPEP conducts various studies of patient experience and outcomes issues in oncology, including retrospective chart review studies, comparative effectiveness work, prospective observational studies and registries, and qualitative research, along with efforts to facilitate the integration of patient-generated health data (PGHD) into routine cancer care processes, such as with electronic patient-reported outcome measures (ePROs) and other mobile health interventions (mHealth). 

This work has led to recognition as an "Inspirational Leader under 40" by the American Academy of Hospice and Palliative Medicine (AAHPM), "Fellow" status from the Academy in 2016, the 2018 international "Clinical Impact Award" from the European Association for Palliative Care, and the AAHPM "Early Career Investigator" award in 2020. I served as 2017-18 Chair of the ASCO Ethics Committee, and currently Chair the Scientific Review Committee of the NIH/NINR-funded Palliative Care Research Cooperative Group (PCRC; www.palliativecareresearch.org). I have served on various national guideline panels for AML and for palliative/supportive care issues in oncology, and was inducted as a Fellow of the American Society of Clinical Oncology (FASCO) in 2021. To date I have published over 150 Medline-indexed articles, and several chapters in prominent textbooks of oncology and palliative medicine.

Education and Training

  • Fellow, Medical Oncology, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Hospice And Palliative Medicine, Duke University School of Medicine, 2011 - 2012
  • Chief Medical Resident, Duke University School of Medicine, 2010 - 2011
  • Resident, Duke University School of Medicine, 2007 - 2009
  • Intern, Duke University School of Medicine, 2006 - 2007
  • M.D., Duke University, 2006

Publications

Nelson, Ashley M., Hermioni L. Amonoo, Alison R. Kavanaugh, Jason A. Webb, Vicki A. Jackson, Julia Rice, Mitchell W. Lavoie, et al. “Palliative care and coping in patients with acute myeloid leukemia: Mediation analysis of data from a randomized clinical trial.” Cancer, August 30, 2021. https://doi.org/10.1002/cncr.33886.

PMID
34460937
Full Text

Singh, Anmol, Susan C. Locke, Steven P. Wolf, Tara A. Albrecht, Jesse D. Troy, Heather Derry, Areej El-Jawahri, and Thomas W. LeBlanc. “The relationship between emotional well-being and understanding of prognosis in patients with acute myeloid leukemia (AML).” Support Care Cancer, August 17, 2021. https://doi.org/10.1007/s00520-021-06499-w.

PMID
34401981
Full Text

Tulsky, James A., Karen E. Steinhauser, Thomas W. LeBlanc, Nick Bloom, Pauline R. Lyna, Jennie Riley, and Kathryn I. Pollak. “Triadic agreement about advanced cancer treatment decisions: Perceptions among patients, families, and oncologists.” Patient Educ Couns, August 4, 2021. https://doi.org/10.1016/j.pec.2021.08.001.

PMID
34384640
Full Text

Amonoo, Hermioni L., Thomas W. LeBlanc, Alison R. Kavanaugh, Jason A. Webb, Lara N. Traeger, Annemarie D. Jagielo, Dagny M. Vaughn, et al. “Posttraumatic stress disorder symptoms in patients with acute myeloid leukemia.” Cancer 127, no. 14 (July 15, 2021): 2500–2506. https://doi.org/10.1002/cncr.33524.

PMID
33764526
Full Text

Hildenbrand, Jordan D., Debra M. Davis, Areej El-Jawahri, Kris W. Herring, Susan C. Locke, Kathryn I. Pollak, Gregory P. Samsa, et al. “A novel decision aid for acute myeloid leukemia: a feasibility and preliminary efficacy trial.” Support Care Cancer 29, no. 7 (July 2021): 3563–69. https://doi.org/10.1007/s00520-020-05864-5.

PMID
33159220
Full Text

Petrilla, Allison A., Anne Shah, Joseph Feliciano, Joseph Woolery, and Thomas W. LeBlanc. “Burden of illness and treatment patterns among patients with peripheral T-cell lymphoma in the US healthcare setting.” Curr Med Res Opin 37, no. 7 (July 2021): 1189–97. https://doi.org/10.1080/03007995.2021.1920380.

PMID
33944646
Full Text

Kwekkeboom, Kristine, Ronald C. Serlin, Sandra E. Ward, Thomas W. LeBlanc, Adeboye Ogunseitan, and James Cleary. “Revisiting patient-related barriers to cancer pain management in the context of the US opioid crisis.” Pain 162, no. 6 (June 1, 2021): 1840–47. https://doi.org/10.1097/j.pain.0000000000002173.

PMID
33337597
Full Text

El-Jawahri, Areej, Thomas W. LeBlanc, and Jennifer S. Temel. “Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia-Moving From Evidence to Practice-Reply.” Jama Oncol 7, no. 6 (June 1, 2021): 943–44. https://doi.org/10.1001/jamaoncol.2021.0709.

PMID
33885719
Full Text

Huggar, D., R. L. Knoth, Z. Cao, C. Lipkin, R. Copher, and T. W. LeBlanc. “ANNUAL HEALTHCARE RESOURCE UTILIZATION AND COSTS IN US PATIENTS DIAGNOSED WITH RELAPSED ACUTE MYELOID LEUKEMIA.” In Value in Health, 24:S28–S28, 2021.

Scholars@Duke

Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos de Castro, Jadee L. Neff, Mitchell E. Horwitz, Thomas W. LeBlanc, et al. “Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.” Blood Cancer J 11, no. 5 (May 16, 2021): 92. https://doi.org/10.1038/s41408-021-00481-9.

PMID
33994546
Full Text

Pages