Infectious Diseases

Thuy Le, MD, PhD

Associate Professor of Medicine
Associate Professor of Molecular Genetics and Microbiology
Affiliate, Duke Global Health Institute
Campus mail 315 Trent Drive, Room #257, Durham, NC 27710
Phone (919) 668-5053
Email address thuy.le@duke.edu

Education and Training

  • Fogarty International Clinical Research Fellowship, National Institutes of Health, 2009 - 2011
  • Infectious Disease Fellowship, Yale University School of Medicine, 2006 - 2009
  • Internal Medicine Residency, Tufts University School of Medicine, 2002 - 2005
  • D.Phil., University of Oxford (UK), 2016
  • M.D., University of Arizona College of Medicine, 2002

Grants

Publications

Le, Thuy, Vo Trieu Ly, Nguyen Thi Mai Thu, Ashley Nguyen, Nguyen Tat Thanh, Nguyen Van Vinh Chau, Guy Thwaites, John Perfect, Ruwanthi Kolamunnage-Dona, and William Hope. “Population Pharmacodynamics of Amphotericin B Deoxycholate for Disseminated Infection Caused by Talaromyces marneffei.” Antimicrob Agents Chemother 63, no. 2 (February 2019). https://doi.org/10.1128/AAC.01739-18.

PMID
30420478
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Jiang, Junjun, Fengxiang Qin, Sirun Meng, Eric J. Nehl, Jinping Huang, Yanfen Liu, Jun Zou, et al. “Effects of cotrimoxazole prophylaxis on Talaromyces marneffei infection in HIV/AIDS patients receiving antiretroviral therapy: a retrospective cohort study.” Emerg Microbes Infect 8, no. 1 (2019): 367–76. https://doi.org/10.1080/22221751.2019.1588078.

PMID
31851879
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Le Ngoc, Chau, Thanh Tran Thi Thanh, Phuong Tran Thi Lan, Trinh Nguyen Mai, Trang Nguyen Hoa, Ngoc Nghiem My, Tan Le Van, et al. “Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.” Plos One 14, no. 3 (2019): e0212734. https://doi.org/10.1371/journal.pone.0212734.

PMID
30865664
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Thanh, N. T., L. D. Vinh, N. T. Liem, C. Shikuma, J. N. Day, G. Thwaites, and T. Le. “Clinical features of three patients with paradoxical immune reconstitution inflammatory syndrome associated with Talaromyces marneffei infection.” Medical Mycology Case Reports 19 (March 1, 2018): 33–37. https://doi.org/10.1016/j.mmcr.2016.12.005.

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Salzer, Helmut J. F., Gerd Burchard, Oliver A. Cornely, Christoph Lange, Thierry Rolling, Stefan Schmiedel, Michael Libman, et al. “Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease.” Respiration 96, no. 3 (2018): 283–301. https://doi.org/10.1159/000489501.

PMID
29953992
Full Text

Le, Thuy, Antoine Adenis, Andrew Limper, and Thomas Harrison. “Itraconazole and antiretroviral therapy: strategies for empirical dosing - Author's reply.” Lancet Infect Dis 17, no. 11 (November 2017): 1123–24. https://doi.org/10.1016/S1473-3099(17)30582-0.

PMID
29115263
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Limper, Andrew H., Antoine Adenis, Thuy Le, and Thomas S. Harrison. “Fungal infections in HIV/AIDS.” Lancet Infect Dis 17, no. 11 (November 2017): e334–43. https://doi.org/10.1016/S1473-3099(17)30303-1.

PMID
28774701
Full Text

Le, Thuy, Nguyen Van Kinh, Ngo T. K. Cuc, Nguyen L. N. Tung, Nguyen T. Lam, Pham T. T. Thuy, Do D. Cuong, et al. “A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis.” N Engl J Med 376, no. 24 (June 15, 2017): 2329–40. https://doi.org/10.1056/NEJMoa1613306.

PMID
28614691
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Armstrong-James, Darius, Tihana Bicanic, Gordon D. Brown, Jennifer C. Hoving, Graeme Meintjes, and Kirsten Nielsen. “AIDS-Related Mycoses: Current Progress in the Field and Future Priorities.” Trends in Microbiology 25, no. 6 (June 2017): 428–30. https://doi.org/10.1016/j.tim.2017.02.013.

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