Uptal Dinesh Patel, MD

Associate Professor of Medicine
Associate Professor in Pediatrics
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, P.O. Box 17969, Durham, NC 27715
Phone (919) 668-8959
Email address uptal.patel@duke.edu

Uptal Patel, MD is an Associate Professor of Medicine and Pediatrics, Director of the Clinical and Translational Core of the Duke O’Brien Center for Kidney Research, and Director of Nephrology Research at the Duke Clinical Research Institute. Dr. Patel has an interest in population health with a broad range of clinical and research experience. As an adult and pediatric nephrologist with training in health services and epidemiology, his work seeks to develop health care systems-level strategies to optimize population management for chronic diseases through improvements in prevention, diagnosis and treatment. In efforts to determine the optimal clinical strategies to manage kidney disease and identify opportunities for improvement in its treatment, Dr. Patel has focused on four inter-related areas that are essential to improving kidney health: i) reducing the progression of chronic kidney disease by improving its detection and management, particularly by leveraging technology to facilitate engagement and self-management; ii) elucidating the inter-relationships between kidney disease and cardiovascular disease, which together amplify the risk of death; iii) improving the evidence in nephrology through comparative effectiveness research, including clinical trials, observational studies, and meta-analyses; and iv) promoting more optimal clinical health policy for all patients with kidney disease. These inter-disciplinary projects have been funded by a variety of public and private sources including the Robert Wood Johnson Foundation, Veterans Affairs, National Institutes of Health, Agency for Healthcare Research & Quality, Food and Drug Administration, Centers for Medicare & Medicaid Services, Renal Physicians Association, and the American Society of Nephrology. 

Education and Training

  • Fellow In Nephrology, Medicine, University of Michigan at Ann Arbor, 2002 - 2003
  • Fellow In Pediatric Nephrology, Pediatrics, University of Michigan at Ann Arbor, 2001 - 2002
  • Medicine/Pediatric Resident, Medicine/Pediatrics, University of Michigan at Ann Arbor, 1997 - 2001
  • M.D., University of California, San Francisco, School of Medicine, 1997

Publications

Tuttle, KR, Bakris, GL, Bilous, RW, Chiang, JL, de Boer, IH, Goldstein-Fuchs, J, Hirsch, IB, Kalantar-Zadeh, K, Narva, AS, Navaneethan, SD, Neumiller, JJ, Patel, UD, Ratner, RE, Whaley-Connell, AT, and Molitch, ME. "Diabetic kidney disease: a report from an ADA Consensus Conference." American journal of kidney diseases : the official journal of the National Kidney Foundation 64, no. 4 (October 2014): 510-533.

PMID
25257325
Full Text

Tuttle, KR, Bakris, GL, Bilous, RW, Chiang, JL, de Boer, IH, Goldstein-Fuchs, J, Hirsch, IB, Kalantar-Zadeh, K, Narva, AS, Navaneethan, SD, Neumiller, JJ, Patel, UD, Ratner, RE, Whaley-Connell, AT, and Molitch, ME. "Diabetic kidney disease: a report from an ADA Consensus Conference." Diabetes care 37, no. 10 (October 2014): 2864-2883.

PMID
25249672
Full Text

Khan, UA, Coca, SG, Hong, K, Koyner, JL, Garg, AX, Passik, CS, Swaminathan, M, Garwood, S, Patel, UD, Hashim, S, Quantz, MA, and Parikh, CR. "Blood transfusions are associated with urinary biomarkers of kidney injury in cardiac surgery." The Journal of thoracic and cardiovascular surgery 148, no. 2 (August 2014): 726-732.

PMID
24820190
Full Text

Hornik, CP, Krawczeski, CD, Zappitelli, M, Hong, K, Thiessen-Philbrook, H, Devarajan, P, Parikh, CR, and Patel, UD. "Serum brain natriuretic peptide and risk of acute kidney injury after cardiac operations in children." The Annals of thoracic surgery 97, no. 6 (June 2014): 2142-2147.

PMID
24725832
Full Text

Coca, SG, Garg, AX, Thiessen-Philbrook, H, Koyner, JL, Patel, UD, Krumholz, HM, Shlipak, MG, and Parikh, CR. "Urinary biomarkers of AKI and mortality 3 years after cardiac surgery." Journal of the American Society of Nephrology : JASN 25, no. 5 (May 2014): 1063-1071.

PMID
24357673
Full Text

Pálsson, R, and Patel, UD. "Cardiovascular complications of diabetic kidney disease." Advances in chronic kidney disease 21, no. 3 (May 2014): 273-280. (Review)

PMID
24780455
Full Text

Patel, UD. "Outcomes after pediatric kidney transplantation improving: how can we do even better?." Pediatrics 133, no. 4 (April 2014): 734-735.

PMID
24616364
Full Text

Stanifer, JW, Jing, B, Tolan, S, Helmke, N, Mukerjee, R, Naicker, S, and Patel, U. "The epidemiology of chronic kidney disease in sub-Saharan Africa: A systematic review and meta-analysis." The Lancet Global Health 2, no. 3 (2014): 174-181.

Full Text

Hornik, CPP, Krawczeski, CD, Zappitelli, M, Hong, K, Thiessen-Philbrook, HR, Devarajan, PV, Parikh, CR, and Patel, UD. "Serum brain natriuretic peptide and risk of acute kidney injury after cardiac operations in children." Annals of Thoracic Surgery 97, no. 6 (January 1, 2014): 2142-2147.

Full Text

Inrig, JK, Califf, RM, Tasneem, A, Vegunta, RK, Molina, C, Stanifer, JW, Chiswell, KE, and Patel, UD. "The landscape of clinical trials in nephrology: A systematic review of clinicaltrials.gov." American Journal of Kidney Diseases 63, no. 5 (January 1, 2014): 771-780.

Full Text

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