Vance Garrison Fowler, MD

Professor of Medicine
Professor in Molecular Genetics and Microbiology
Member in the Duke Clinical Research Institute
Campus mail Duke Box 102359, Hanes House, Trent Drive, Durham, NC 27710
Phone (919) 613-5678
Email address fowle003@mc.duke.edu

Determinants of Outcome in Patients with Staphylococcus aureus Bacteremia
Pathogenesis of Bacterial Infections
Infections due to Resistant Gram Positive Organisms
Tropical medicine/International Health

Education and Training

  • Fellow, Infectious Diseases, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 1999
  • M.D., University of North Carolina at Chapel Hill, 1993

Publications

Evans, SR, Follmann, D, Liu, Y, Holland, T, Doernberg, SB, Rouphael, N, Hamasaki, T, Jiang, Y, Lok, JJ, Tran, TTT, Harris, AD, Fowler, VG, Boucher, H, Kreiswirth, BN, Bonomo, RA, van Duin, D, Paterson, DL, and Chambers, H. "Sequential Multiple Assignment Randomized Trials for COMparing Personalized Antibiotic StrategieS (SMART-COMPASS)." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America (October 23, 2018).

PMID
30351426
Full Text

Doernberg, SB, Tran, TTT, Tong, SYC, Paul, M, Yahav, D, Davis, JS, Leibovici, L, Boucher, HW, Corey, GR, Cosgrove, SE, Chambers, HF, Fowler, VG, Evans, SR, Holland, TL, and Antibacterial Resistance Leadership Group, . "Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America (October 12, 2018).

PMID
30321315
Full Text

Chan, LC, Rossetti, M, Miller, LS, Filler, SG, Johnson, CW, Lee, HK, Wang, H, Gjertson, D, Fowler, VG, Reed, EF, Yeaman, MR, and MRSA Systems Immunobiology Group, . "Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory." Proceedings of the National Academy of Sciences of the United States of America (October 8, 2018).

PMID
30297395
Full Text

Scott, WK, Medie, FM, Ruffin, F, Sharma-Kuinkel, BK, Cyr, DD, Guo, S, Dykxhoorn, DM, Skov, RL, Bruun, NE, Dahl, A, Lerche, CJ, Petersen, A, Larsen, AR, Lauridsen, TK, Johansen, HK, Ullum, H, Sørensen, E, Hassager, C, Bundgaard, H, Schønheyder, HC, Torp-Pedersen, C, Østergaard, LB, Arpi, M, Rosenvinge, F, Erikstrup, LT, Chehri, M, Søgaard, P, Andersen, PS, and Fowler, VG. "Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia." Plos Genetics 14, no. 10 (October 5, 2018): e1007667-null.

PMID
30289878
Full Text

Evans, SR, Tran, TTT, Hujer, AM, Hill, CB, Hujer, KM, Mediavilla, JR, Manca, C, Domitrovic, TN, Perez, F, Farmer, M, Pitzer, KM, Wilson, BM, Kreiswirth, BN, Patel, R, Jacobs, MR, Chen, L, Fowler, VG, Chambers, HF, Bonomo, RA, and Antibacterial Resistance Leadership Group (ARLG), . "Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam against Pseudomonas aeruginosa: PRIMERS IV." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America (September 20, 2018).

PMID
30239599
Full Text

Holland, TL, Chambers, HF, Boucher, HW, Corey, GR, Coleman, R, Castaneda-Ruiz, B, and Fowler, VG. "Considerations for Clinical Trials of Staphylococcus aureus Bloodstream Infection in Adults." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America (September 10, 2018).

PMID
30202941
Full Text

Holland, TL, Raad, I, Boucher, HW, Anderson, DJ, Cosgrove, SE, Aycock, PS, Baddley, JW, Chaftari, A-M, Chow, S-C, Chu, VH, Carugati, M, Cook, P, Corey, GR, Crowley, AL, Daly, J, Gu, J, Hachem, R, Horton, J, Jenkins, TC, Levine, D, Miro, JM, Pericas, JM, Riska, P, Rubin, Z, Rupp, ME, Schrank, J, Sims, M, Wray, D, Zervos, M, Fowler, VG, and Staphylococcal Bacteremia Investigators, . "Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial." Jama 320, no. 12 (September 2018): 1249-1258.

PMID
30264119
Full Text

Guimaraes, AO, Cao, Y, Hong, K, Mayba, O, Peck, M, Gutierrez, J, Ruffin, F, Carrasco-Triguero, M, Dinoso, JB, Clemenzi-Allen, A, Koss, CA, Maskarinec, S, Chambers, HF, Fowler, VG, Baruch, A, and Rosenberger, CM. "A prognostic model of persistent bacteremia and mortality in complicated S. aureus bloodstream infection." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America (August 25, 2018).

PMID
30165412
Full Text

Maskarinec, SA, Parlak, Z, Tu, Q, Levering, V, Zauscher, S, López, GP, Fowler, VG, and Perfect, JR. "On-demand release of Candida albicans biofilms from urinary catheters by mechanical surface deformation." Biofouling 34, no. 6 (July 2018): 595-604.

PMID
29897277
Full Text

Ojewole, AA, Jou, JD, Fowler, VG, and Donald, BR. "BBK* (Branch and Bound Over K*): A Provable and Efficient Ensemble-Based Protein Design Algorithm to Optimize Stability and Binding Affinity Over Large Sequence Spaces." Journal of Computational Biology : a Journal of Computational Molecular Cell Biology 25, no. 7 (July 2018): 726-739.

PMID
29641249
Full Text

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