Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Wang, Jiaonan, Tiantian Li, Yuebin Lv, Virginia Byers Kraus, Yi Zhang, Chen Mao, Zhaoxue Yin, et al. “Fine Particulate Matter and Poor Cognitive Function among Chinese Older Adults: Evidence from a Community-Based, 12-Year Prospective Cohort Study.” Environ Health Perspect 128, no. 6 (June 2020): 67013. https://doi.org/10.1289/EHP5304.

PMID
32551881
Full Text

Zhang, Yi, Tiantian Li, Runmei Ma, Zhaoxue Yin, Jiaonan Wang, Mike Z. He, Dandan Xu, et al. “Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort.” Sci Total Environ 717 (May 15, 2020): 137191. https://doi.org/10.1016/j.scitotenv.2020.137191.

PMID
32062280
Full Text

Goode, Adam P., Todd A. Schwartz, Virginia B. Kraus, Janet L. Huebner, Steven Z. George, Rebecca J. Cleveland, Richard Gracely, et al. “Inflammatory, Structural, and Pain Biochemical Biomarkers May Reflect Radiographic Disc Space Narrowing: The Johnston County Osteoarthritis Project.” J Orthop Res 38, no. 5 (May 2020): 1027–37. https://doi.org/10.1002/jor.24534.

PMID
31750565
Full Text

Hsueh, M. -. F., M. P. Bolognesi, S. S. Wellman, and V. B. Kraus. “Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells.” Osteoarthritis Cartilage 28, no. 5 (May 2020): 639–45. https://doi.org/10.1016/j.joca.2020.01.013.

PMID
32028022
Full Text

Huang, ZeYu, Jing Chen, BoLei Li, Benhua Zeng, Ching-Heng Chou, Xin Zheng, JingWei Xie, et al. “Faecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice.” Ann Rheum Dis 79, no. 5 (May 2020): 646–56. https://doi.org/10.1136/annrheumdis-2019-216471.

PMID
32205337
Full Text

Han, Ashley J., Louie C. Alexander, Janet L. Huebner, Alexander B. Reed, and Virginia B. Kraus. “Increase in Free and Total Plasma TGF-β1 Following Physical Activity.” Cartilage, April 27, 2020, 1947603520916523. https://doi.org/10.1177/1947603520916523.

PMID
32340467
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Kimmerling, Kelly A., Sara J. Oswald, Janet L. Huebner, Dianne Little, Virginia B. Kraus, Jing X. Kang, Chia-Lung Wu, and Farshid Guilak. “Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis.” Arthritis Res Ther 22, no. 1 (April 15, 2020): 83. https://doi.org/10.1186/s13075-020-02170-7.

PMID
32295649
Full Text

Yuan, Jin-Qiu, Yue-Bin Lv, Virginia Byers Kraus, Xiang Gao, Zhao-Xue Yin, Hua-Shuai Chen, Jie-Si Luo, Yi Zeng, Chen Mao, and Xiao-Ming Shi. “Number of natural teeth, denture use and mortality in Chinese elderly: a population-based prospective cohort study.” Bmc Oral Health 20, no. 1 (April 10, 2020): 100. https://doi.org/10.1186/s12903-020-01084-9.

PMID
32276615
Full Text

Lv, Yuebin, Jinhui Zhou, Virginia Byers Kraus, Tiantian Li, Jeremy A. Sarnat, Jiaonan Wang, Yang Liu, et al. “Long-term exposure to PM2.5 and incidence of disability in activities of daily living among oldest old.” Environ Pollut 259 (April 2020): 113910. https://doi.org/10.1016/j.envpol.2020.113910.

PMID
32023791
Full Text

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