Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Dominick, K. L., J. M. Jordan, J. B. Renner, and V. B. Kraus. “Relationships of radiographic and clinical variables to pinch and grip strength among patients with osteoarthritis.” In Arthritis and Rheumatism, 50:S147–48. WILEY-LISS, 2004.

Scholars@Duke

McDaniel, G. E., T. P. Vail, and V. B. Kraus. “Comparison of knee alignment angle by x-ray and goniometer..” In Arthritis and Rheumatism, 50:S343–S343. WILEY-LISS, 2004.

Scholars@Duke

Jordan, J. M., V. B. Kraus, J. B. Renner, G. Luta, A. D. Dragomir, M. Ionescu, T. Lobanok, L. King, and A. R. Poole. “Predictive ability of serum biomarkers of types I and II collagen cleavage and aggrecan turnover in incidence and progression of radiographic knee osteoarthritis in African Americans and Caucasians..” In Arthritis and Rheumatism, 50:S481–S481. WILEY-LISS, 2004.

Scholars@Duke

Varjú, G., C. F. Pieper, J. B. Renner, and V. B. Kraus. “Assessment of hand osteoarthritis: correlation between thermographic and radiographic methods..” Rheumatology (Oxford) 43, no. 7 (July 2004): 915–19. https://doi.org/10.1093/rheumatology/keh204.

PMID
15126670
Full Text

Kraus, V. B., Y. -. J. Li, E. R. Martin, J. M. Jordan, J. B. Renner, M. Doherty, A. G. Wilson, et al. “Articular hypermobility is a protective factor for hand osteoarthritis..” Arthritis Rheum 50, no. 7 (July 2004): 2178–83. https://doi.org/10.1002/art.20354.

PMID
15248215
Full Text

Kraus, Virginia B., Janet L. Huebner, Thomas Stabler, Charlene M. Flahiff, Lori A. Setton, Christian Fink, Vladimir Vilim, and Amy G. Clark. “Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model..” Arthritis Rheum 50, no. 6 (June 2004): 1822–31. https://doi.org/10.1002/art.20291.

PMID
15188359
Full Text

Guilak, Farshid, Beverley Fermor, Francis J. Keefe, Virginia B. Kraus, Steven A. Olson, David S. Pisetsky, Lori A. Setton, and J Brice Weinberg. “The role of biomechanics and inflammation in cartilage injury and repair..” Clin Orthop Relat Res, no. 423 (June 2004): 17–26. https://doi.org/10.1097/01.blo.0000131233.83640.91.

PMID
15232421
Full Text

Flahiff, Charlene M., Virginia B. Kraus, Janet L. Huebner, and Lori A. Setton. “Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method..” Osteoarthritis Cartilage 12, no. 5 (May 2004): 383–88. https://doi.org/10.1016/j.joca.2004.01.007.

PMID
15094137
Full Text

Jordan, Joanne M., Virginia B. Kraus, and Marc C. Hochberg. “Genetics of osteoarthritis..” Curr Rheumatol Rep 6, no. 1 (February 2004): 7–13.

PMID
14713397
Scholars@Duke

Eckstein, F., R. J. Buck, H. C. Charles, M. Hudelmaier, W. Wirth, V. B. Kraus, and J. L. Evelhoch. “Improved precision of quantitative cartilage measurements with magnetic resonance imaging at 3 T.” In Osteoarthritis and Cartilage, 12:S119–S119. W B SAUNDERS CO LTD, 2004.

Scholars@Duke

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