Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982


Little, D., C. L. Wu, D. Jain, J. McNeill, J. Anderson, J. Huebner, R. Rodriguiz, W. Wetsel, V. Kraus, and F. Guilak. “Omega-3 Fatty Acids Mitigate Obesity-induced Osteoarthritis And Accelerate Wound Repair.,” n.d.


Kraus, V. B. “Preclinical Osteoarthritis,” n.d.


Kraus, V. B. “Rare Osteoarthritis: Ochronosis and Kashin-Beck Disease.” Rheumatology, 6th Edition, Ed. Mc Hochberg, Aj Silman, Js Smolen, Me Weinblatt, Mh Weisman (Mosby Elsevier, Philadelphia). 2014;Chapter 185:1536 1540., n.d.