Vivian Hou Chu, MD

Associate Professor
Member in the Duke Clinical Research Institute
Campus mail Duke Box 102359, Div of Infectious Diseases, Durham, NC 27710
Phone (919) 668-7174
Email address vivian.chu@duke.edu

Dr. Chu's clinical research is focused on staphylococci and endocarditis (IE).  She is the director of the International Collaboration on Endocarditis (ICE), a group of investigators from 78 sites in 32 countries worldwide that is dedicated to further the understanding of infective endocarditis.  The ICE database comprises > 5000 cases of endocarditis and is designed to answer questions that could not be answered from a single-center study. The current focus of this group is surgical-decision making in the treatment of endocarditis. Another major focus of Dr. Chu's research is on the relationship between oral hygiene and risk for developing infective endocarditis.

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 2003 - 2006
  • Medical Resident, Medicine, Duke University, 2000 - 2003
  • M.D., Columbia University, 2000

Publications

Pericàs, JM, Messina, JA, Garcia-de-la-Mària, C, Park, L, Sharma-Kuinkel, BK, Marco, F, Wray, D, Kanafani, ZA, Carugati, M, Durante-Mangoni, E, Tattevin, P, Chu, VH, Moreno, A, Fowler, VG, Miró, JM, and International Collaboration on Endocarditis Microbiology Investigators, . "Influence of vancomycin minimum inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus left-sided infective endocarditis treated with antistaphylococcal β-lactam antibiotics: a prospective cohort study by the International Collaboration on Endocarditis." Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 23, no. 8 (August 2017): 544-549.

PMID
28159672
Full Text

Carugati, M, Petti, CA, Arnold, C, Miro, JM, Pericàs, JM, Garcia de la Maria, C, Kanafani, Z, Durante-Mangoni, E, Baddley, J, Wray, D, Klein, JL, Delahaye, F, Fernandez-Hidalgo, N, Hannan, MM, Murdoch, D, Bayer, A, and Chu, VH. "Antistaphylococcal β-Lactams versus Vancomycin for Treatment of Infective Endocarditis Due to Methicillin-Susceptible Coagulase-Negative Staphylococci: a Prospective Cohort Study from the International Collaboration on Endocarditis." Antimicrobial agents and chemotherapy 60, no. 10 (October 2016): 6341-6349.

PMID
27527083
Full Text

Romaine, A, Ye, D, Ao, Z, Fang, F, Johnson, O, Blake, T, Benjamin, DK, Cotten, CM, Testoni, D, Clark, RH, Chu, VH, Smith, PB, Hornik, CP, and Best Pharmaceuticals for Children Act – Pediatric Trials Network, . "Safety of histamine-2 receptor blockers in hospitalized VLBW infants." Early human development 99 (August 2016): 27-30.

PMID
27390109
Full Text

Limeres Posse, J, Álvarez Fernández, M, Fernández Feijoo, J, Medina Henríquez, J, Lockhart, PB, Chu, VH, and Diz Dios, P. "Intravenous amoxicillin/clavulanate for the prevention of bacteraemia following dental procedures: a randomized clinical trial." The Journal of antimicrobial chemotherapy 71, no. 7 (July 2016): 2022-2030.

PMID
27029851
Full Text

Park, LP, Chu, VH, Peterson, G, Skoutelis, A, Lejko-Zupa, T, Bouza, E, Tattevin, P, Habib, G, Tan, R, Gonzalez, J, Altclas, J, Edathodu, J, Fortes, CQ, Siciliano, RF, Pachirat, O, Kanj, S, Wang, A, and International Collaboration on Endocarditis (ICE) Investigators, . "Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis." Journal of the American Heart Association 5, no. 4 (April 18, 2016): e003016-.

PMID
27091179
Full Text

Gulack, BC, Laughon, MM, Clark, RH, Burgess, T, Robinson, S, Muhammad, A, Zhang, A, Davis, A, Morton, R, Chu, VH, Arnold, CJ, Hornik, CP, and Smith, PB. "Enteral Feeding with Human Milk Decreases Time to Discharge in Infants following Gastroschisis Repair." The Journal of pediatrics 170 (March 2016): 85-89.

PMID
26703875
Full Text

Tsalik, EL, Li, Y, Hudson, LL, Chu, VH, Himmel, T, Limkakeng, AT, Katz, JN, Glickman, SW, McClain, MT, Welty-Wolf, KE, Fowler, VG, Ginsburg, GS, Woods, CW, and Reed, SD. "Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients." Annals of the American Thoracic Society 13, no. 3 (March 2016): 401-413.

PMID
26700878
Full Text

Qi, R, Joo, H-S, Sharma-Kuinkel, B, Berlon, NR, Park, L, Fu, C-L, Messina, JA, Thaden, JT, Yan, Q, Ruffin, F, Maskarinec, S, Warren, B, Chu, VH, Fortes, CQ, Giannitsioti, E, Durante-Mangoni, E, Kanafani, ZA, Otto, M, and Fowler, VG. "Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus." The Journal of infection 72, no. 3 (March 2016): 302-308.

PMID
26778460
Full Text

Chu, VH. "When the Cat's Out of the Bag: Searching for Portals of Entry in Infective Endocarditis." Journal of the American College of Cardiology 67, no. 2 (January 2016): 159-161.

PMID
26791062
Full Text

Chu, VH, Park, LP, Athan, E, Delahaye, F, Freiberger, T, Lamas, C, Miro, JM, Mudrick, DW, Strahilevitz, J, Tribouilloy, C, Durante-Mangoni, E, Pericas, JM, Fernández-Hidalgo, N, Nacinovich, F, Rizk, H, Krajinovic, V, Giannitsioti, E, Hurley, JP, Hannan, MM, Wang, A, and ICE Investigators, . "Response to Letter Regarding Article, "Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis"." Circulation 132, no. 14 (October 2015): e184-e185. (Letter)

PMID
26438777
Full Text

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