Vivian Hou Chu, MD

Associate Professor
Member in the Duke Clinical Research Institute
Campus mail Duke Box 102359, DIV of Infectious Diseases, Durham, NC 27710
Phone (919) 668-7174
Email address vivian.chu@duke.edu

Dr. Chu's clinical research is focused on staphylococci and endocarditis (IE).  She is the director of the International Collaboration on Endocarditis (ICE), a group of investigators from 78 sites in 32 countries worldwide that is dedicated to further the understanding of infective endocarditis.  The ICE database comprises > 5000 cases of endocarditis and is designed to answer questions that could not be answered from a single-center study. The current focus of this group is surgical-decision making in the treatment of endocarditis. Another major focus of Dr. Chu's research is on the relationship between oral hygiene and risk for developing infective endocarditis.

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 2003 - 2006
  • Medical Resident, Medicine, Duke University, 2000 - 2003
  • M.D., Columbia University, 2000

Publications

Chirouze, Catherine, François Alla, Vance G. Fowler, Daniel J. Sexton, G Ralph Corey, Vivian H. Chu, Andrew Wang, et al. “Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the International Collaboration of Endocarditis-Prospective Cohort Study..” Clin Infect Dis 60, no. 5 (March 1, 2015): 741–49. https://doi.org/10.1093/cid/ciu871.

PMID
25389255
Full Text

Delahaye, F., V. H. Chu, J. Altclas, B. Barsic, A. Delahaye, T. Freiberger, D. L. Gordon, et al. “One-year outcome following biological or mechanical valve replacement for infective endocarditis..” Int J Cardiol 178 (January 15, 2015): 117–23. https://doi.org/10.1016/j.ijcard.2014.10.125.

PMID
25464234
Full Text

Chu, Vivian H., Lawrence P. Park, Eugene Athan, Francois Delahaye, Tomas Freiberger, Cristiane Lamas, Jose M. Miro, et al. “Association between surgical indications, operative risk, and clinical outcome in infective endocarditis: a prospective study from the International Collaboration on Endocarditis..” Circulation 131, no. 2 (January 13, 2015): 131–40. https://doi.org/10.1161/CIRCULATIONAHA.114.012461.

PMID
25480814
Full Text

Alagna, L., L. P. Park, B. P. Nicholson, A. J. Keiger, J. Strahilevitz, A. Morris, D. Wray, et al. “Repeat endocarditis: analysis of risk factors based on the International Collaboration on Endocarditis - Prospective Cohort Study..” Clin Microbiol Infect 20, no. 6 (June 2014): 566–75. https://doi.org/10.1111/1469-0691.12395.

PMID
24102907
Full Text

Bin Abdulhak, Aref A., Larry M. Baddour, Patricia J. Erwin, Bruno Hoen, Vivian H. Chu, George A. Mensah, and Imad M. Tleyjeh. “Global and regional burden of infective endocarditis, 1990-2010: a systematic review of the literature..” Glob Heart 9, no. 1 (March 2014): 131–43. https://doi.org/10.1016/j.gheart.2014.01.002.

PMID
25432123
Full Text

Carugati, Manuela, Arnold S. Bayer, Josè M. Miró, Lawrence P. Park, Armenio C. Guimarães, Athanasios Skoutelis, Claudio Q. Fortes, et al. “High-dose daptomycin therapy for left-sided infective endocarditis: a prospective study from the international collaboration on endocarditis..” Antimicrob Agents Chemother 57, no. 12 (December 2013): 6213–22. https://doi.org/10.1128/AAC.01563-13.

PMID
24080644
Full Text

Chirouze, C., E. Athan, F. Alla, V. H. Chu, G. Ralph Corey, C. Selton-Suty, M. -. L. Erpelding, et al. “Enterococcal endocarditis in the beginning of the 21st century: analysis from the International Collaboration on Endocarditis-Prospective Cohort Study..” Clin Microbiol Infect 19, no. 12 (December 2013): 1140–47. https://doi.org/10.1111/1469-0691.12166.

PMID
23517406
Full Text

Lalani, Tahaniyat, Vivian H. Chu, Lawrence P. Park, Enrico Cecchi, G Ralph Corey, Emanuele Durante-Mangoni, Vance G. Fowler, et al. “In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis..” Jama Intern Med 173, no. 16 (September 9, 2013): 1495–1504. https://doi.org/10.1001/jamainternmed.2013.8203.

PMID
23857547
Full Text

Delahaye, F., V. H. Chu, B. Hoen, C. A. Mestres, P. Pappas, M. Santos, and A. Wang. “Association between type of valve prosthesis and one year mortality in IE: an analysis of 1467 patients from the International collaboration on endocarditis prospective cohort study.” In European Heart Journal, 34:861–62. OXFORD UNIV PRESS, 2013.

Scholars@Duke

Pages