William J. Fulkerson, MD

Professor of Medicine
Campus mail 108 Davison Bldg, Durham, NC 27710
Phone (919) 684-1860
Email address fulke003@mc.duke.edu

Currently I am involved with the NHLBI ARDS Network in research involving acute lung injury and acute respiratory distress syndrome (ARDS). The ARDS Network, composed of Duke and nine other centers, continues the study of mechanical ventilation strategies in patients with severe acute lung injury. Patients are randomized to usual care versus modes of ventilation designed to avoid over distension of the lung. Planning is underway for an additional NHLBI-sponsored randomized trial to examine the role of pulmonary artery catheterization in critically ill patients. Additionally I am involved in clinical trials looking at patients with sepsis, severe respiratory failure, and other common problems in an intensive care unit setting. These investigations concern decision-making, outcome prediction, and cost-effectiveness of care in the intensive care unit.

Key Words include:

1. ARDS
2. Bronchoscopy
3. Critical Care
4. Outcome Predictions
5. Sepsis

Education and Training

  • M.D., University of North Carolina at Chapel Hill, 1977

Publications

Ackerly, DC, Sangvai, DG, Udayakumar, K, Shah, BR, Kalman, NS, Cho, AH, Schulman, KA, Fulkerson, WJ, and Dzau, VJ. "Training the next generation of physician-executives: an innovative residency pathway in management and leadership." Academic Medicine 86, no. 5 (May 2011): 575-579. (Review)

PMID
21436663
Full Text

Halperin, Edward C., William J. Fulkerson, Russel Kaufman, Paul Newman, and Gary L. Stiles. “Should an academic radiation oncologist be allowed to "opt out" of medicare?.” Journal of the American College of Radiology : Jacr 2, no. 10 (October 2005): 841–45. https://doi.org/10.1016/j.jacr.2005.03.009.

PMID
17411944
Full Text

Halperin, E. C., W. J. Fulkerson, R. Kaufman, P. Newman, and G. L. Stiles. “Should an academic radiation oncologist be allowed to "opt out" of Medicare?.” Journal of the American College of Radiology 2, no. 10 (2005): 841–45. https://doi.org/10.1016/j.jacr.2005.03.009.

Full Text

Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome..” Critical Care Medicine 30, no. 1 (January 2002): 1–6.

PMID
11902249
Scholars@Duke

Knudsen, N. W., W. J. Fulkerson, and M. W. Sebastian. “Family communication enhanced by 24 hour in house intensivists.” Critical Care Medicine 28, no. 12 (December 1, 2000): A109–A109.

Scholars@Duke

Acute Respiratory Distress Syndrome Network, D. J., Roy G. Brower, Michael A. Matthay, Alan Morris, David Schoenfeld, B Taylor Thompson, and Arthur Wheeler. “Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome..” In The New England Journal of Medicine, 342:1301–8, 2000. https://doi.org/10.1056/nejm200005043421801.

PMID
10793162
Full Text

Galanos, A. N., C. F. Pieper, P. S. Kussin, M. T. Winchell, W. J. Fulkerson, F. E. Harrell, J. M. Teno, et al. “Relationship of body mass index to subsequent mortality among seriously ill hospitalized patients.” Critical Care Medicine 25, no. 12 (December 1, 1997): 1962–68. https://doi.org/10.1097/00003246-199712000-00010.

Full Text

Galanos, A. N., C. F. Pieper, P. S. Kussin, M. T. Winchell, W. J. Fulkerson, F. E. Harrell, J. M. Teno, et al. “Relationship of body mass index to subsequent mortality among seriously ill hospitalized patients. SUPPORT Investigators. The Study to Understand Prognoses and Preferences for Outcome and Risks of Treatments..” Critical Care Medicine 25, no. 12 (December 1997): 1962–68. https://doi.org/10.1097/00003246-199712000-00010.

PMID
9403743
Full Text

Cooper, G. S., P. Bellamy, N. V. Dawson, N. Desbiens, W. J. Fulkerson, L. Goldman, L. M. Quinn, T. Speroff, and C. S. Landefeld. “A prognostic model for patients with end-stage liver disease..” In Gastroenterology, 113:1278–88, 1997. https://doi.org/10.1053/gast.1997.v113.pm9322523.

PMID
9322523
Full Text

Fulkerson, W. J., and G. R. Bernard. “Right heart catheterization in acute respiratory failure..” New Horizons (Baltimore, Md.) 5, no. 3 (August 1997): 239–43.

PMID
9259337
Scholars@Duke

Pages