Yeh-Chung Chang, MD

Assistant Professor of Pediatrics
Assistant Professor of Medicine
Email address dan.chang@duke.edu

My interests include infections in immunocompromised hosts and I help run the Pediatric Transplant ID clinical service. At Duke, these populations include pediatric solid organ transplant recipients, bone marrow transplant recipients, and Oncology patients. My personal research includes EBV infection and post-transplant lymphoprolifeartive disease (PTLD), as well as vaccine responses in the immunocompromised host populations. I am also involved in studies evaluating invasive fungal infections and pharmacokinetics of antifungal medications.

Education and Training

  • Infectious Diseases Fellowship, Pediatrics, Children's Hospital of Philadelphia, 2014 - 2017
  • Residency, Pediatrics, University of Texas Southwestern Medical Center, Medical School, 2010 - 2013
  • M.D., Rutgers, Robert Wood Johnson Medical School, 2010

Publications

Kilgore, Jacob T., Bradford Becken, Matthew G. Varga, Suhag Parikh, Vinod Prasad, Debra Lugo, and Yeh-Chung Chang. “Use of Letermovir for Salvage Therapy for Resistant Cytomegalovirus in a Pediatric Hematopoietic Stem Cell Transplant Recipient.” J Pediatric Infect Dis Soc 9, no. 4 (September 17, 2020): 486–89. https://doi.org/10.1093/jpids/piz050.

PMID
31362308
Full Text

Akinboyo, Ibukunoluwa C., Rebecca R. Young, Lisa P. Spees, Sarah M. Heston, Michael J. Smith, Yeh-Chung Chang, Lauren E. McGill, et al. “Microbiology and Risk Factors for Hospital-Associated Bloodstream Infections Among Pediatric Hematopoietic Stem Cell Transplant Recipients.” Open Forum Infectious Diseases 7, no. 4 (April 2020): ofaa093. https://doi.org/10.1093/ofid/ofaa093.

PMID
32284949
Full Text

Chang, Yeh-Chung, Erin Graf, and Abby M. Green. “Invasive Curvularia Infection in Pediatric Patients With Hematologic Malignancy Identified by Fungal Sequencing.” J Pediatric Infect Dis Soc 8, no. 1 (March 28, 2019): 87–91. https://doi.org/10.1093/jpids/piy092.

PMID
30265347
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Mitchell, Stephanie L., Yeh-Chung Chang, Kristen Feemster, and Ana María Cárdenas. “Implementation of a rapid influenza A/B and RSV direct molecular assay improves emergency department oseltamivir use in paediatric patients.” Journal of Medical Microbiology 67, no. 3 (March 1, 2018): 358–63. https://doi.org/10.1099/jmm.0.000676.

Full Text

He, Fanglian, Gauri R. Nair, Cinque S. Soto, Yehchung Chang, Lillian Hsu, Erik Ronzone, William F. DeGrado, and Andrew N. Binns. “Molecular basis of ChvE function in sugar binding, sugar utilization, and virulence in Agrobacterium tumefaciens.” J Bacteriol 191, no. 18 (September 2009): 5802–13. https://doi.org/10.1128/JB.00451-09.

PMID
19633083
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Mazari, Peter M., Daniela Linder-Basso, Anindita Sarangi, Yehchung Chang, and Monica J. Roth. “Single-round selection yields a unique retroviral envelope utilizing GPR172A as its host receptor.” Proc Natl Acad Sci U S A 106, no. 14 (April 7, 2009): 5848–53. https://doi.org/10.1073/pnas.0809741106.

PMID
19307586
Full Text