Sponsored Research
Adrian F. Hernandez of Cardiology has received a sub-award through the Massachusetts General Hospital for a project entitled "Mapping the Stroke Transfer Network in the Northeast for Identification of System-level factors Associated with the Quality of Acute Stroke Care Delivery NCE." Total funding will be $28,901.
Robert W. McGarrah III of Cardiology has received an award (1K08-HL135275-01A1) from the National Institutes of Health for a project entitled "The Branched Chain Ketoacid Dehydrogenase Kinase-Phosphatase System as a New Regulatory Node in Mycocardial Fuel Section." Total funding will be $713,030.
Richard H. Lee of Endocrinology, Metabolism, and Nutrition has received an award (1K23-AG058797-01) from the National Institutes of Health for a project entitled "Metabolomic & Radiographic Markers of Fracture Risk among Older Adults with Diabetes." Total funding will be $541,667.
Diego Bohorquez of Gastroenterology has received an award from the American Gastroenterological Association for a project entitled "Role of TLRs in human enteroendocrine cells." Total funding will be $25,000.
Rowena J. Dolor of General Internal Medicine has received a sub-award (PLC-1609-36277) through Oregon Health & Science University for a project entitled "A Cluster-Randomized Trial Comparing Team-Based Versus Primary Care Clinician-Focused Advance Care Planning in Practice-Based Research Networks." Total funding will be $90,264.
Yi Zeng of Geriatrics has received an award (P01-AG031719-07S1) from the National Institutes of Health for a project entitled "Sex differences in effects of genetics & GxE interactions on elderly cognition, mental health and survival." Total funding will be $103,006.
Nelson J. Chao of Hematologic Malignancies and Cellular Therapy has received an award (1UG3-TR002448-01) from the National Institutes of Health for a project entitled "AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease." Total funding will be $474,721.
Nicholas Devito (Mentor: Brent A. Hanks) of Medical Oncology has received an award from the Damon Runyon Cancer Research Foundation for a project entitled "Investigating the Role of EMT-mediated Dendritic Cell Tolerization in Checkpoint Inhibitor Resistance." Total funding will be $460,000.
Jeremy Force of Medical Oncology has received an award from the North Carolina Biotechnology Center for a project entitled "3D Biology Signatures defined by Nanostring Max System." Total funding will be $181,000.
Brent A. Hanks of Medical Oncology has received a sub-award (2-UM1CA154967-07) through the Fred Hutchinson Cancer Research Center for a project entitled "Phase II Pilot Trial of an Indoleamine 2, 3,diosygenase -1 (IDO1) Inhibitor (INCBO24360) Plus a Multipeptide Melanoma Vaccine (MELTAC 12.1) in Patients with Advanced Melanoma (CITN-04)." Total funding will be $7,000.
Michael R. Harrison of Medical Oncology has received an award through the University of North Carolina - Chapel Hill for a project entitled "Phase II Single Arm Study of Gemcitabine and Cisplatin plus Pembrolizumab as Neoadjuvant Therapy Prior to Radical Cystectomy in Patients with Muscle-Invasive Bladder Cancer." Total funding will be $82,500.
Arif H. Kamal of Medical Oncology has received a sub-award (R01CA215188) through the Massachusetts General Hospital for a project entitled "Randomized Trial of Stepped Palliative Care versus Early Integrated Palliative Care in Patients with Advanced Lung Cancer." Total funding will be $134,260.
Andrew B. Nixon of Medical Oncology has received an award for a project entitled "Immunoprofiling of CALGB 80405." Total funding will be $300,000.
Kevin C. Oeffinger of Medical Oncology has received an award (2R01-CA134722-06A1) from the National Institutes of Health for a project entitled "EMPOWER Study: Promoting BC Screening in Women Who Survived Childhood Cancer." Total funding will be $3,072,928.
Alexander Grabner of Nephrology has received an award from the American Society of Nephrology for a project entitled "The role of FGF23 and FGFR4 in cardio-renal syndrome." Total funding will be $100,000.
Myles Wolf of Nephrology has received a sub-award (5R01-DK102438-04) through the Northwestern University for a project entitled "Impact of phosphate and FGF23 reduction on intermediate end points in CKD." Total funding will be $21,750.
Christopher Cox of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R21-NR016743-01A1) from the National Institutes of Health for a project entitled "Needs and triggers: improving intensive care unit-based palliative care delivery." Total funding will be $440,563.
Ankoor Shah of Rheumatology and Immunology has received a sub-award through the University of Alabama at Birmingham for a project entitled "Validation of an Algorithm to Identify Incident Interstitial Lung Disease in Patients with Rheumatoid Arthritis." Total funding will be $26,171.
Industry-sponsored Clinical Trials
Adam D. Devore of Cardiology has received an award from the Intra-Cellular Therapies, Inc. for a project entitled "ITI-214-104." Total funding will be $170,641.
Camille G. Frazier-Mills of Cardiology has received an award from Medtronic, Inc. for a project entitled "MICRA Trans-Catheter." Total funding will be $7,000.
Raymond J. Kim of Cardiology has received an award from Merck Sharp & Dohme for a project entitled "Victoria CMR Substudy - Core Lab." Total funding will be $462,336.
Renato D. Lopes of Cardiology has received an award from Amgen, Inc. for a project entitled "a retrospective re-review of all negatively adjudicated events (NAE) across three (3) protocols/studies." Total funding will be $186,606.
Ann M. Navar of Cardiology has received an award from Amarin Corporation for a project entitled "Hypertriglyceridemia Observational Studies." Total funding will be $450,000.
Chetan B. Patel of Cardiology has received an award from Corvia Medical, Inc. for a project entitled "REDUCE LAP-HF." Total funding will be $393,553.
Thomas J. Povsic of Cardiology has received an award from Intra-Cellular Therapies, Inc. for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of Escalating Single Doses of ITI-214 in Patients with Systolic Heart Failure." Total funding will be $1,007,182.
Matthew T. Roe of Cardiology has received an award from MyoKardia, Inc. for a project entitled "MYK-461-005: Start-up Budget." Total funding will be $1,033,385.
Matthew T. Roe of Cardiology has received an award from MyoKardia, Inc. for a project entitled "MAVERICK-HCM." Total funding will be $295,316.
Rajesh Swaminathan of Cardiology has received an award from ACIST Medical Systems, Inc. for a project entitled "Adenosine Contrast CorrELations in Evaluating RevAscularizaTION." Total funding will be $999,999.
Andrew Wang of Cardiology has received an award from Abbott Vascular Devices for a project entitled "COAPT Continued Access Study (CAS)." Total funding will be $47,900.
Tracy Y. Wang of Cardiology has received an award from the American College of Cardiology Foundation for a project entitled "NCDR-ACTION Patient Navigator." Total funding will be $36,731.
Manal F. Abdelmalek of Gastroenterology has received an award from Intercept Pharmaceuticals, Inc for a project entitled "A Phase 1, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis with Fibrosis." Total funding will be $96,339.
Manal F. Abdelmalek of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "Gilead 454-4378 A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib, GS-0976, GS-9674, and Combinations in Subjects with Bridging (F3) Fibrosis or Compensated Cirrhosis (F4) due to NASH." Total funding will be $193,996.
Diego Bohorquez of Gastroenterology has received an award from Caribou Biosciences, Inc. for a project entitled "Steering Brain Behaviors Using Programmable Bacteria." Total funding will be $160,000.
Danielle M. Brander of Hematologic Malignancies and Cellular Therapy has received an award from Zhejiang DTRM Biopharma Co.Ltd. for a project entitled "Phase 1a/1b Study of a Novel BTK Inhibitor, DTRMWXHS-12, and Combination Products, CTRM-505 and DTRM-555, in Patients with Chronic Lymphocytic Leukemia or Other B-Cell Lymphomas." Total funding will be $248,348.
Cristina Gasparetto of Hematologic Malignancies and Cellular Therapy has received an award from Pfizer, Inc. for a project entitled "A Phase 1, Open Label Study to evaluate the safety Pharmacokinetic, Pharmacodynamic and clinical activity of PF-06863135, A B-Cell Maturation Antigen (BCMA) - CD3 Bispecifi Antibody In Patient." Total funding will be $504,369.
Cristina Gasparetto of Hematologic Malignancies and Cellular Therapy has received an award from F. Hoffmann-La Roche Ltd for a project entitled "Open-Label, Multicenter, Dose-Escalation Expansion Phase IB study to Evaluate Safety, Pharmacokinetics, and activity of BET Inhibitor RO6870810, Given as Mono- and combination Therapy to patients with Advanced Multiple Myeloma." Total funding will be $725,906.
Dorothy Sipkins of Hematologic Malignancies and Cellular Therapy has received an award from GlycoMimetics, Inc for a project entitled "Studying the Effects of Combined E-selectin and CXCR4 Inhibition on Breast Cancer Cell Immune Recognition." Total funding will be $134,441.
Thomas L. Ortel of Hematology has received an award from Diagnostica Stago for a project entitled "ThRombosis exelUsion STudy for STA - Liatest D-DiXL (TRUST)." Total funding will be $53,130.
John Perfect of Infectious Diseases has received an award from Amplyx Pharmaceuticals, Inc. for a project entitled "An open-label study to evaluate the efficacy and safety of APX001 in non-neutropenic patients with candidemia, with or without invasive candidiasis, inclusive of patients with suspected resistance to standard of care antifungal treatment." Total funding will be $5,500.
Megan E. Reller of Infectious Diseases has received a sub-award (HHSO100201600014C) through InBios International, Inc. for a project entitled "InBios Zika Study." Total funding will be $235,882.
Daniel J. George of Medical Oncology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "Bayer Prototype Prostate Program - 3 Day Programming." Total funding will be $85,451.
Thomas Stinchcombe of Medical Oncology has received an award from AstraZeneca LP for a project entitled "A Single Arm Phase II Study Osimertinib in Patients with Stage 4 Non-small Cell Lung Cancer with Uncommon EGFR Mutations Thoracic Oncology Program (TOP) Protocol Number: TOP 1703." Total funding will be $212,573.
John H. Strickler of Medical Oncology has received an award from AbbVie Inc. for a project entitled "A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Anti-Tumor Activity ofABBV-321 in Subjects with Advanced Solid Tumors Associated with Overexpression of the Epidermal Growth Factor Receptor (EGFR) or its Ligands." Total funding will be $700,356.
Tian Zhang of Medical Oncology has received an award from Merck for a project entitled "A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Pembrolizumab (MK-3475) as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy (KEYNOTE-564)." Total funding will be $504,273.
Robert M. Tighe of Pulmonary, Allergy, and Critical Care Medicine has received an award from Genentech, Inc. for a project entitled "GA39831: An observational study to assess disease relevant outcomes using home monitoring devices in patients with idiopathic pulmonary fibrosis." Total funding will be $54,183.
Jennifer Rogers of Rheumatology and Immunology has received an award from Gilead Sciences, Inc. for a project entitled "A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Filgotinib and GS-9876 in Female Subjects with Moderately-to-Severely Active Cutaneous Lupus Erythematosus (CLE)." Total funding will be $160,685.